Handbook of Arsenic Toxicology, Second Edition presents the latest findings on arsenic, including its chemistry, sources and effects on the environment and human health. The book discusses both acute and chronic effects, discussing many aspects of arsenic, from physical and chemical properties, exposure, epidemiology, organ toxicity, diagnosis, prevention and treatment. Fully updated and revised, this new edition includes new topics on risk assessment, molecular mechanisms of arsenic, advances in the integrated approach to testing, assessment and development, evaluation and application of high content predictive models, and new alternative methods (NAMS) in the context of Adverse Outcome Pathways (AOPs) to assess toxicology.
This comprehensive resource allows readers to effectively assess the risks related to arsenic, providing them with all they need to know on arsenic exposure, toxicity and toxicity prevention.
1. Handbook of Arsenic Toxicology - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iv 5. Copyright - p. Page v 6. Dedication - p. Page vi 7. Contributors - p. Page vi 8. Preface - p. Page x 9. List of Illustrations - p. Page xvi 10. List of Tables - p. Page xvii 11. 1 : Arsenic: Chemistry, occurrence, and exposure - p. Page xvii 12. 2 : Groundwater arsenic contamination and its health effects in Bangladesh - p. Page 43 13. 3 : Arsenic and fluorescent humic substances in the groundwater of Bangladesh: A public health risk - p. Page 71 14. 4 : Arsenic risk assessment - p. Page 97 15. 5 : Evaluation of sol-gel-modified activated alumina adsorbent for arsenic removal from drinking water - p. Page 118 16. 6 : Health effects of chronic arsenic toxicity - p. Page 147 17. 7 : Changing concept of arsenic toxicity with development of speciation techniques - p. Page 185 18. 8 : Mechanism for arsenic-induced toxic effects - p. Page 213 19. 9 : Arsenic-induced mutagenesis and carcinogenesis: A possible mechanism - p. Page 242 20. 10 : Arsenic through the gastrointestinal tract - p. Page 286 21. 11 : Advances in cutaneous toxicology of arsenic - p. Page 320 22. 12 : Arsenic-induced liver injury - p. Page 347 23. 13 : Arsenic and respiratory disease - p. Page 372 24. 14 : Arsenical kidney toxicity - p. Page 389 25. 15 : Arsenic-induced developmental neurotoxicity - p. Page 401 26. 16 : Developmental arsenic exposure impacts fetal programming of the nervous system - p. Page 426 27. 17 : Health effects of preconception, prenatal, and early-life exposure to inorganic arsenic - p. Page 447 28. 18 : Arsenic, kidney, and urinary bladder disorders - p. Page 472 29. 19 : Developmental arsenic exposure: Behavioral dysfunctions and neurochemical perturbations - p. Page 495 30. 20 : Arsenic and cardiovascular system - p. Page 509 31. 21 : An update on the immunotoxic effects of arsenic exposure - p. Page 541 32. 22 : Arsenic and developmental toxicity and reproductive disorders - p. Page 584 33. 23 : Arsenic and cancer - p. Page 600 34. 24 : The association between chronic arsenic exposure and type 2 diabetes: A metaanalysis - p. Page 623 35. 25 : Arsenic biosensors: Challenges and opportunities for high-throughput detection - p. Page 644 36. 26 : Medical countermeasures—Chelation therapy - p. Page 661 37. 27 : Biochemical and molecular basis of arsenic toxicity and tolerance in microbes and plants - p. Page 697 38. 28 : Arsenic in the marine environment—Contents, speciation, and its biotransformation - p. Page 742 39. 29 : Environmental toxicology of arsenic to wildlife (nonhuman species): Exposure, accumulation, toxicity, and regulations - p. Page 782 40. 30 : Integrated approach to testing and assessment and development in arsenic toxicology - p. Page 812 41. 31 : Integrated approaches to testing and assessment during the development of arsenic toxicology - p. Page 852 42. 32 : High content predictive models and new alternative methods (NAMs) in the context of adverse outcome pathways (AOPs) to assess arsenic toxicology - p. Page 879 43. 33 : Arsenic toxicity on nonhuman species - p. Page 895 44. Index - p. Page 920
Handbook of Arsenic Toxicology, Second Edition presents the latest findings on arsenic, including its chemistry, sources and effects on the environment and human health. The book discusses both acute and chronic effects, discussing many aspects of arsenic, from physical and chemical properties, exposure, epidemiology, organ toxicity, diagnosis, prevention and treatment. Fully updated and revised, this new edition includes new topics on risk assessment, molecular mechanisms of arsenic, advances in the integrated approach to testing, assessment and development, evaluation and application of high content predictive models, and new alternative methods (NAMS) in the context of Adverse Outcome Pathways (AOPs) to assess toxicology.
This comprehensive resource allows readers to effectively assess the risks related to arsenic, providing them with all they need to know on arsenic exposure, toxicity and toxicity prevention.
1. Handbook of Arsenic Toxicology - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page i 4. Table of Contents - p. Page iv 5. Copyright - p. Page v 6. Dedication - p. Page vi 7. Contributors - p. Page vi 8. Preface - p. Page x 9. List of Illustrations - p. Page xvi 10. List of Tables - p. Page xvii 11. 1 : Arsenic: Chemistry, occurrence, and exposure - p. Page xvii 12. 2 : Groundwater arsenic contamination and its health effects in Bangladesh - p. Page 43 13. 3 : Arsenic and fluorescent humic substances in the groundwater of Bangladesh: A public health risk - p. Page 71 14. 4 : Arsenic risk assessment - p. Page 97 15. 5 : Evaluation of sol-gel-modified activated alumina adsorbent for arsenic removal from drinking water - p. Page 118 16. 6 : Health effects of chronic arsenic toxicity - p. Page 147 17. 7 : Changing concept of arsenic toxicity with development of speciation techniques - p. Page 185 18. 8 : Mechanism for arsenic-induced toxic effects - p. Page 213 19. 9 : Arsenic-induced mutagenesis and carcinogenesis: A possible mechanism - p. Page 242 20. 10 : Arsenic through the gastrointestinal tract - p. Page 286 21. 11 : Advances in cutaneous toxicology of arsenic - p. Page 320 22. 12 : Arsenic-induced liver injury - p. Page 347 23. 13 : Arsenic and respiratory disease - p. Page 372 24. 14 : Arsenical kidney toxicity - p. Page 389 25. 15 : Arsenic-induced developmental neurotoxicity - p. Page 401 26. 16 : Developmental arsenic exposure impacts fetal programming of the nervous system - p. Page 426 27. 17 : Health effects of preconception, prenatal, and early-life exposure to inorganic arsenic - p. Page 447 28. 18 : Arsenic, kidney, and urinary bladder disorders - p. Page 472 29. 19 : Developmental arsenic exposure: Behavioral dysfunctions and neurochemical perturbations - p. Page 495 30. 20 : Arsenic and cardiovascular system - p. Page 509 31. 21 : An update on the immunotoxic effects of arsenic exposure - p. Page 541 32. 22 : Arsenic and developmental toxicity and reproductive disorders - p. Page 584 33. 23 : Arsenic and cancer - p. Page 600 34. 24 : The association between chronic arsenic exposure and type 2 diabetes: A metaanalysis - p. Page 623 35. 25 : Arsenic biosensors: Challenges and opportunities for high-throughput detection - p. Page 644 36. 26 : Medical countermeasures—Chelation therapy - p. Page 661 37. 27 : Biochemical and molecular basis of arsenic toxicity and tolerance in microbes and plants - p. Page 697 38. 28 : Arsenic in the marine environment—Contents, speciation, and its biotransformation - p. Page 742 39. 29 : Environmental toxicology of arsenic to wildlife (nonhuman species): Exposure, accumulation, toxicity, and regulations - p. Page 782 40. 30 : Integrated approach to testing and assessment and development in arsenic toxicology - p. Page 812 41. 31 : Integrated approaches to testing and assessment during the development of arsenic toxicology - p. Page 852 42. 32 : High content predictive models and new alternative methods (NAMs) in the context of adverse outcome pathways (AOPs) to assess arsenic toxicology - p. Page 879 43. 33 : Arsenic toxicity on nonhuman species - p. Page 895 44. Index - p. Page 920
