Edited and written by top experts and pioneers in dialysis, Handbook of Dialysis Therapy, 6th Edition, provides the entire dialysis team with a comprehensive overview of this growing field. It covers traditional and advanced procedures, what pitfalls to expect and how to overcome them, and how best to treat various patient populations—all with a practical approach that can be directly applied to patient care. This must-have resource has been updated with the latest cutting-edge technology, dialysis techniques, and complications related to various diseases for both pediatric and adult patients.
Explains complex dialysis concepts through abundant diagrams, photos, line drawings, and tables, while its readable, hands-on approach allows for quick review of key information.
Covers both adult and pediatric patients in detail, and offers guidance on special populations such as the geriatric patients and the chronically ill.
Features increased content on home-based dialysis modalities, new alternatives for establishing vascular access for hemodialysis, new protocols for reducing the risk of infection and complications, and advancements in establishing and managing peritoneal dialysis.
Includes extensive pediatric content such as prevention and treatment of bone disease, management of anemia, assessing quality of life in pediatric patients undergoing dialysis, and immunizations in children undergoing dialysis.
Defines the quality imperatives, roles, and responsibilities of dialysis facility medical directors and attending nephrologists.
Updates nephrologists on the latest alternative dialysis modalities.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. iv 5. Dedication - p. v 6. Contributors - p. vii 7. Preface - p. xxiii 8. Part I: Dialysis Therapy for Adults - p. xxiii 9. Section 1: Overview of ESKD - p. xxiii 10. 1: Demographics of the End-Stage Renal Disease Patient - p. 3 11. 2: Uremic Toxicity - p. 16 12. 3: Initiation of Dialysis Therapy - p. 45 13. Section 2: Hemodialysis - p. 53 14. 4: Urea Kinetic Modeling for Guiding Hemodialysis Therapy in Adults - p. 56 15. 5: The Dialysis Prescription - p. 67 16. 6: Selecting a Dialyzer: Technical and Clinical Considerations - p. 72 17. 7: Water Treatment Equipment for In-Center Hemodialysis - p. 80 18. 8: Dialysate Composition - p. 93 19. 9: Safety Monitors in Hemodialysis - p. 101 20. 10: Methods of Hemodialysis Anticoagulation - p. 118 21. 11: Common Clinical Problems in Hemodialysis - p. 126 22. 12: Hemofiltration and Hemodiafiltration - p. 135 23. 13: Wearable and Implantable Renal Replacement Therapy - p. 141 24. 14: Home Preparation and Installation for Home Hemodialysis - p. 149 25. 15: Vascular Access - p. 154 26. 16: Cannulation of Arteriovenous Vascular Access: Science and Art - p. 165 27. 17: Central Venous Access for Hemodialysis - p. 183 28. 18: Noninfectious Complications From Vascular Access - p. 192 29. 19: Infectious Complications From Vascular Access - p. 198 30. Section 3: Peritoneal Dialysis - p. 210 31. 20: Determination of Continuous Ambulatory Peritoneal Dialysis and Automated Peritoneal Dialysis Prescriptions - p. 212 32. 21: Peritoneal Dialysis Cyclers and Other Mechanical Devices - p. 216 33. 22: Peritoneal Dialysis Solutions - p. 222 34. 23: Solute Management With Peritoneal Dialysis - p. 230 35. 24: Volume Management With Peritoneal Dialysis - p. 237 36. 25: Peritoneal Access Devices, Placement Techniques, and Maintenance - p. 254 37. 26: Peritoneal Catheter Exit Site and Tunnel Infections - p. 268 38. 27: Peritonitis in Peritoneal Dialysis - p. 272 39. 28: Abdominal Hernias With Peritoneal Dialysis - p. 279 40. 29: Dialysate Leaks with Peritoneal Dialysis - p. 284 41. 30: Hydrothorax and Peritoneal Dialysis - p. 288 42. 31: Abdominal Catastrophes, Peritoneal Eosinophilia, and Other Unusual Events in Peritoneal Dialysis - p. 292 43. 32: Metabolic Complications of Peritoneal Dialysis - p. 296 44. Section 4: Management of Uremic Complications - p. 299 45. 33: Acid–Base Homeostasis in Dialysis - p. 301 46. 34: Nutritional Management of Hemodialysis Patients - p. 308 47. 35: Intradialytic Parenteral Nutrition and Intraperitoneal Nutrition - p. 315 48. 36: Nutritional Management in Peritoneal Dialysis - p. 332 49. 37: Anemia and Its Treatment in Patients With End-Stage Kidney Disease - p. 341 50. 38: Resistance to Erythropoiesis Stimulating Agent (ESA) Treatment - p. 351 51. 39: Chronic Kidney Disease–Mineral and Bone Disorder - p. 363 52. 40: Phosphate Management in Patients with End-Stage Kidney Disease - p. 372 53. 41: Use of Vitamin D Sterols and Calcimimetics in Patients With End-Stage Renal Disease - p. 378 54. 42: Parathyroidectomy - p. 381 55. 43: Acquired Cystic Kidney Disease - p. 389 56. Section 5: Management of Co-Existing Illnesses and Special Populations - p. 391 57. 44: The Challenges of Blood Pressure Control in Hemodialysis Patients - p. 393 58. 45: Arrhythmias in Hemodialysis Patients - p. 406 59. 46: Management of Ischemic Heart Disease, Heart Failure, and Pericarditis in Patients Undergoing Long-Term Dialysis - p. 413 60. 47: Avoidance and Treatment of Cardiovascular Disease in Dialysis - p. 421 61. 48: Management of Dyslipidemia in Long-Term Dialysis Patients - p. 430 62. 49: End-Stage Kidney Failure in the Diabetic Patient - p. 434 63. 50: Care of Elderly Dialysis and End-Stage Kidney Disease Patients - p. 452 64. 51: Liver Disease and Gastrointestinal Disorders in Dialysis Patients - p. 460 65. 52: Abnormalities of Thyroid Function in Chronic Dialysis Patients - p. 466 66. 53: Care of the Human Immunodeficiency Virus–Infected End-Stage Kidney Disease Patient - p. 481 67. 54: COVID-19 and Dialysis Patients - p. 491 68. 55: Psychosocial Issues in Patients Treated With Dialysis - p. 497 69. 56: Evaluation and Treatment of Sexual Dysfunction - p. 507 70. 57: Pregnancy in Dialysis Patients - p. 513 71. 58: Principles of Drug Usage in Dialysis Patients - p. 530 72. 59: Medication Management - p. 574 73. 60: Physical Activity, Function, and Exercise-Based Rehabilitation for People on Dialysis - p. 582 74. 61: Physical, Psychosocial, and Vocational Rehabilitation of Patients Undergoing Long-Term Dialysis - p. 590 75. 62: Preventive Care in End-Stage Renal Disease - p. 596 76. Section 6: Systems Management for the Care of Dialysis Patients - p. 604 77. 63: Ethical Considerations in the Care of Dialysis Patients: The New Paradigm - p. 606 78. 64: Improving Outcomes for End-Stage Renal Disease Patients: Shifting the Quality Paradigm - p. 613 79. 65: Quality, Safety, Accountability, and Medical Director Responsibilities - p. 619 80. 66: Application of Telemedicine to Kidney Failure Patients - p. 629 81. Section 7: Acute Kidney Injury and Poisonings - p. 635 82. 67: Continuous Renal Replacement Therapies for Acute Kidney Injury - p. 637 83. 68: Anticoagulation for Continuous Renal Replacement Therapy - p. 653 84. 69: Treatment of Poisoning with Extracorporeal Methods - p. 659 85. Part II: Dialysis Therapy for Children - p. 667 86. 70: Vascular Access and Peritoneal Dialysis Catheter Placement in Children - p. 669 87. 71: Infant Hemodialysis - p. 680 88. 72: Urea Kinetic Modeling for Hemodialysis Prescription in Children - p. 684 89. 73: Alternate Hemodialysis Prescriptions in Children - p. 689 90. 74: Anticoagulation in Children Undergoing Hemodialysis, Continuous Renal Replacement Therapy, or Apheresis Therapy - p. 694 91. 75: Prescribing Peritoneal Dialysis in Children - p. 700 92. 76: Nutritional Management of Children Undergoing Peritoneal Dialysis - p. 705 93. 77: Peritoneal Dialysis in Neonates and Infants - p. 712 94. 78: Dialysis for Inborn Errors of Metabolism - p. 719 95. 79: Neurocognitive Function in Pediatric Dialysis - p. 724 96. 80: Growth in Children With End-Stage Kidney Disease - p. 729 97. 81: Adequacy of Peritoneal Dialysis/Assessing Peritoneal Function in Pediatric Patients - p. 741 98. 82: Continuous Renal Replacement Therapy in Pediatric Patients - p. 749 99. 83: Prevention and Treatment of Bone Disease in Pediatric Dialysis Patients - p. 768 100. 84: Management of Anemia in Children Undergoing Dialysis - p. 778 101. 85: Prevention and Treatment of Cardiovascular Complications in Children Undergoing Dialysis - p. 789 102. 86: Infectious Complications in Children Undergoing Dialysis - p. 794 103. 87: Caring for the Teenager in an Adult Unit - p. 804 104. Index - p. 809
Edited and written by top experts and pioneers in dialysis, Handbook of Dialysis Therapy, 6th Edition, provides the entire dialysis team with a comprehensive overview of this growing field. It covers traditional and advanced procedures, what pitfalls to expect and how to overcome them, and how best to treat various patient populations—all with a practical approach that can be directly applied to patient care. This must-have resource has been updated with the latest cutting-edge technology, dialysis techniques, and complications related to various diseases for both pediatric and adult patients.
Explains complex dialysis concepts through abundant diagrams, photos, line drawings, and tables, while its readable, hands-on approach allows for quick review of key information.
Covers both adult and pediatric patients in detail, and offers guidance on special populations such as the geriatric patients and the chronically ill.
Features increased content on home-based dialysis modalities, new alternatives for establishing vascular access for hemodialysis, new protocols for reducing the risk of infection and complications, and advancements in establishing and managing peritoneal dialysis.
Includes extensive pediatric content such as prevention and treatment of bone disease, management of anemia, assessing quality of life in pediatric patients undergoing dialysis, and immunizations in children undergoing dialysis.
Defines the quality imperatives, roles, and responsibilities of dialysis facility medical directors and attending nephrologists.
Updates nephrologists on the latest alternative dialysis modalities.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. iv 5. Dedication - p. v 6. Contributors - p. vii 7. Preface - p. xxiii 8. Part I: Dialysis Therapy for Adults - p. xxiii 9. Section 1: Overview of ESKD - p. xxiii 10. 1: Demographics of the End-Stage Renal Disease Patient - p. 3 11. 2: Uremic Toxicity - p. 16 12. 3: Initiation of Dialysis Therapy - p. 45 13. Section 2: Hemodialysis - p. 53 14. 4: Urea Kinetic Modeling for Guiding Hemodialysis Therapy in Adults - p. 56 15. 5: The Dialysis Prescription - p. 67 16. 6: Selecting a Dialyzer: Technical and Clinical Considerations - p. 72 17. 7: Water Treatment Equipment for In-Center Hemodialysis - p. 80 18. 8: Dialysate Composition - p. 93 19. 9: Safety Monitors in Hemodialysis - p. 101 20. 10: Methods of Hemodialysis Anticoagulation - p. 118 21. 11: Common Clinical Problems in Hemodialysis - p. 126 22. 12: Hemofiltration and Hemodiafiltration - p. 135 23. 13: Wearable and Implantable Renal Replacement Therapy - p. 141 24. 14: Home Preparation and Installation for Home Hemodialysis - p. 149 25. 15: Vascular Access - p. 154 26. 16: Cannulation of Arteriovenous Vascular Access: Science and Art - p. 165 27. 17: Central Venous Access for Hemodialysis - p. 183 28. 18: Noninfectious Complications From Vascular Access - p. 192 29. 19: Infectious Complications From Vascular Access - p. 198 30. Section 3: Peritoneal Dialysis - p. 210 31. 20: Determination of Continuous Ambulatory Peritoneal Dialysis and Automated Peritoneal Dialysis Prescriptions - p. 212 32. 21: Peritoneal Dialysis Cyclers and Other Mechanical Devices - p. 216 33. 22: Peritoneal Dialysis Solutions - p. 222 34. 23: Solute Management With Peritoneal Dialysis - p. 230 35. 24: Volume Management With Peritoneal Dialysis - p. 237 36. 25: Peritoneal Access Devices, Placement Techniques, and Maintenance - p. 254 37. 26: Peritoneal Catheter Exit Site and Tunnel Infections - p. 268 38. 27: Peritonitis in Peritoneal Dialysis - p. 272 39. 28: Abdominal Hernias With Peritoneal Dialysis - p. 279 40. 29: Dialysate Leaks with Peritoneal Dialysis - p. 284 41. 30: Hydrothorax and Peritoneal Dialysis - p. 288 42. 31: Abdominal Catastrophes, Peritoneal Eosinophilia, and Other Unusual Events in Peritoneal Dialysis - p. 292 43. 32: Metabolic Complications of Peritoneal Dialysis - p. 296 44. Section 4: Management of Uremic Complications - p. 299 45. 33: Acid–Base Homeostasis in Dialysis - p. 301 46. 34: Nutritional Management of Hemodialysis Patients - p. 308 47. 35: Intradialytic Parenteral Nutrition and Intraperitoneal Nutrition - p. 315 48. 36: Nutritional Management in Peritoneal Dialysis - p. 332 49. 37: Anemia and Its Treatment in Patients With End-Stage Kidney Disease - p. 341 50. 38: Resistance to Erythropoiesis Stimulating Agent (ESA) Treatment - p. 351 51. 39: Chronic Kidney Disease–Mineral and Bone Disorder - p. 363 52. 40: Phosphate Management in Patients with End-Stage Kidney Disease - p. 372 53. 41: Use of Vitamin D Sterols and Calcimimetics in Patients With End-Stage Renal Disease - p. 378 54. 42: Parathyroidectomy - p. 381 55. 43: Acquired Cystic Kidney Disease - p. 389 56. Section 5: Management of Co-Existing Illnesses and Special Populations - p. 391 57. 44: The Challenges of Blood Pressure Control in Hemodialysis Patients - p. 393 58. 45: Arrhythmias in Hemodialysis Patients - p. 406 59. 46: Management of Ischemic Heart Disease, Heart Failure, and Pericarditis in Patients Undergoing Long-Term Dialysis - p. 413 60. 47: Avoidance and Treatment of Cardiovascular Disease in Dialysis - p. 421 61. 48: Management of Dyslipidemia in Long-Term Dialysis Patients - p. 430 62. 49: End-Stage Kidney Failure in the Diabetic Patient - p. 434 63. 50: Care of Elderly Dialysis and End-Stage Kidney Disease Patients - p. 452 64. 51: Liver Disease and Gastrointestinal Disorders in Dialysis Patients - p. 460 65. 52: Abnormalities of Thyroid Function in Chronic Dialysis Patients - p. 466 66. 53: Care of the Human Immunodeficiency Virus–Infected End-Stage Kidney Disease Patient - p. 481 67. 54: COVID-19 and Dialysis Patients - p. 491 68. 55: Psychosocial Issues in Patients Treated With Dialysis - p. 497 69. 56: Evaluation and Treatment of Sexual Dysfunction - p. 507 70. 57: Pregnancy in Dialysis Patients - p. 513 71. 58: Principles of Drug Usage in Dialysis Patients - p. 530 72. 59: Medication Management - p. 574 73. 60: Physical Activity, Function, and Exercise-Based Rehabilitation for People on Dialysis - p. 582 74. 61: Physical, Psychosocial, and Vocational Rehabilitation of Patients Undergoing Long-Term Dialysis - p. 590 75. 62: Preventive Care in End-Stage Renal Disease - p. 596 76. Section 6: Systems Management for the Care of Dialysis Patients - p. 604 77. 63: Ethical Considerations in the Care of Dialysis Patients: The New Paradigm - p. 606 78. 64: Improving Outcomes for End-Stage Renal Disease Patients: Shifting the Quality Paradigm - p. 613 79. 65: Quality, Safety, Accountability, and Medical Director Responsibilities - p. 619 80. 66: Application of Telemedicine to Kidney Failure Patients - p. 629 81. Section 7: Acute Kidney Injury and Poisonings - p. 635 82. 67: Continuous Renal Replacement Therapies for Acute Kidney Injury - p. 637 83. 68: Anticoagulation for Continuous Renal Replacement Therapy - p. 653 84. 69: Treatment of Poisoning with Extracorporeal Methods - p. 659 85. Part II: Dialysis Therapy for Children - p. 667 86. 70: Vascular Access and Peritoneal Dialysis Catheter Placement in Children - p. 669 87. 71: Infant Hemodialysis - p. 680 88. 72: Urea Kinetic Modeling for Hemodialysis Prescription in Children - p. 684 89. 73: Alternate Hemodialysis Prescriptions in Children - p. 689 90. 74: Anticoagulation in Children Undergoing Hemodialysis, Continuous Renal Replacement Therapy, or Apheresis Therapy - p. 694 91. 75: Prescribing Peritoneal Dialysis in Children - p. 700 92. 76: Nutritional Management of Children Undergoing Peritoneal Dialysis - p. 705 93. 77: Peritoneal Dialysis in Neonates and Infants - p. 712 94. 78: Dialysis for Inborn Errors of Metabolism - p. 719 95. 79: Neurocognitive Function in Pediatric Dialysis - p. 724 96. 80: Growth in Children With End-Stage Kidney Disease - p. 729 97. 81: Adequacy of Peritoneal Dialysis/Assessing Peritoneal Function in Pediatric Patients - p. 741 98. 82: Continuous Renal Replacement Therapy in Pediatric Patients - p. 749 99. 83: Prevention and Treatment of Bone Disease in Pediatric Dialysis Patients - p. 768 100. 84: Management of Anemia in Children Undergoing Dialysis - p. 778 101. 85: Prevention and Treatment of Cardiovascular Complications in Children Undergoing Dialysis - p. 789 102. 86: Infectious Complications in Children Undergoing Dialysis - p. 794 103. 87: Caring for the Teenager in an Adult Unit - p. 804 104. Index - p. 809
