Handbook of Immunoassay Technologies: Approaches, Performances, and Applications, Second Edition unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays to the smartphone-based point-of-care formats. The book discusses how advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies that have paved the way for next-generation immunoassays.
Revised and updated, the second edition of Handbook of Immunoassay Technologies: Approaches, Performances, and Applications covers all the relevant, timely, and important developments in the field. This edition offers new content on topics such as antibody production for immunodiagnostics, multiplex immunoassays, chemiluminescent immunoassays, immunoassays for newborn screening, and immunoassays of viruses like SARS-CoV-2, HIV, Ebola, and Hepatitis C. The addition of these new topics as well as up-to-date content make the second edition a valuable and comprehensive resource on immunoassays.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xvii 7. Preface - p. xix 8. Chapter 1. Immunoassays: an overview - p. 1 9. Chapter 2. Antibody immobilization and surface functionalization chemistries for immunodiagnostics - p. 19 10. Chapter 3. Monoclonal antibody generation by phage display: history, state-of-the-art, and future - p. 45 11. Chapter 4. Bioanalytical requirements and regulatory guidelines for immunoassays - p. 83 12. Chapter 5. Enzyme-linked immunoassays - p. 99 13. Chapter 6. Chemiluminescent immunoassays (CLIA) - p. 131 14. Chapter 7. Lateral flow immunoassays - p. 143 15. Chapter 8. Paper-based immunoassays - p. 173 16. Chapter 9. Acoustic wave–based immunoassays - p. 193 17. Chapter 10. Interferometry-based immunoassays - p. 231 18. Chapter 11. Nanomaterial- and micromaterial-based immunoassays - p. 261 19. Chapter 12. Microcantilever-based sensors - p. 293 20. Chapter 13. Quartz crystal microbalance–based sensors - p. 319 21. Chapter 14. Electrochemical immunosensors fundamentals and applications in clinical diagnostics - p. 345 22. Chapter 15. Lab-on-a-chip immunoassays - p. 401 23. Chapter 16. Smartphone-based immunoassays - p. 419 24. Chapter 17. Multiplex immunoassays - p. 441 25. Chapter 18. Immunoassays for newborn screening - p. 461 26. Chapter 19. Biotin interference in immunoassays and strategies to tackle it - p. 475 27. Chapter 20. In vitro diagnostic immunoassays for SARS-CoV-2 - p. 487 28. Chapter 21. Immunoassays of human immunodeficiency virus (HIV) - p. 503 29. Chapter 22. Immunoassays of hepatitis C virus (HCV) - p. 519 30. Chapter 23. Immunoassays for Ebola virus disease - p. 531 31. Chapter 24. Immunoassays of botulism neurotoxins (BoNTs) of Clostridia - p. 549 32. Chapter 25. Immunoassays of biological warfare agents - p. 567 33. Chapter 26. Lateral flow immunoassays with improved detection sensitivity - p. 587 34. Chapter 27. Immunoassays: future prospects and possibilities - p. 607 35. Index - p. 621
Handbook of Immunoassay Technologies: Approaches, Performances, and Applications, Second Edition unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays to the smartphone-based point-of-care formats. The book discusses how advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies that have paved the way for next-generation immunoassays.
Revised and updated, the second edition of Handbook of Immunoassay Technologies: Approaches, Performances, and Applications covers all the relevant, timely, and important developments in the field. This edition offers new content on topics such as antibody production for immunodiagnostics, multiplex immunoassays, chemiluminescent immunoassays, immunoassays for newborn screening, and immunoassays of viruses like SARS-CoV-2, HIV, Ebola, and Hepatitis C. The addition of these new topics as well as up-to-date content make the second edition a valuable and comprehensive resource on immunoassays.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xvii 7. Preface - p. xix 8. Chapter 1. Immunoassays: an overview - p. 1 9. Chapter 2. Antibody immobilization and surface functionalization chemistries for immunodiagnostics - p. 19 10. Chapter 3. Monoclonal antibody generation by phage display: history, state-of-the-art, and future - p. 45 11. Chapter 4. Bioanalytical requirements and regulatory guidelines for immunoassays - p. 83 12. Chapter 5. Enzyme-linked immunoassays - p. 99 13. Chapter 6. Chemiluminescent immunoassays (CLIA) - p. 131 14. Chapter 7. Lateral flow immunoassays - p. 143 15. Chapter 8. Paper-based immunoassays - p. 173 16. Chapter 9. Acoustic wave–based immunoassays - p. 193 17. Chapter 10. Interferometry-based immunoassays - p. 231 18. Chapter 11. Nanomaterial- and micromaterial-based immunoassays - p. 261 19. Chapter 12. Microcantilever-based sensors - p. 293 20. Chapter 13. Quartz crystal microbalance–based sensors - p. 319 21. Chapter 14. Electrochemical immunosensors fundamentals and applications in clinical diagnostics - p. 345 22. Chapter 15. Lab-on-a-chip immunoassays - p. 401 23. Chapter 16. Smartphone-based immunoassays - p. 419 24. Chapter 17. Multiplex immunoassays - p. 441 25. Chapter 18. Immunoassays for newborn screening - p. 461 26. Chapter 19. Biotin interference in immunoassays and strategies to tackle it - p. 475 27. Chapter 20. In vitro diagnostic immunoassays for SARS-CoV-2 - p. 487 28. Chapter 21. Immunoassays of human immunodeficiency virus (HIV) - p. 503 29. Chapter 22. Immunoassays of hepatitis C virus (HCV) - p. 519 30. Chapter 23. Immunoassays for Ebola virus disease - p. 531 31. Chapter 24. Immunoassays of botulism neurotoxins (BoNTs) of Clostridia - p. 549 32. Chapter 25. Immunoassays of biological warfare agents - p. 567 33. Chapter 26. Lateral flow immunoassays with improved detection sensitivity - p. 587 34. Chapter 27. Immunoassays: future prospects and possibilities - p. 607 35. Index - p. 621
