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Handbook of the Behavioral Neurobiology of Serotonin, Second Edition, builds on the success of the first edition by continuing to provide a detailed and comprehensive overview of the many facets of behavioral serotonin research. The text expands on the two key topics, behavioral control (sensory processing, ultrasonic vocalization, and melatonin and sleep control) and psychiatric disorders, including its role on psychostimulant abuse and addiction. The new edition includes two new sections on the serotonin systems interactions and the involvement of serotonin in neurological disorders and associated treatment.

Serotonin is a major neurotransmitters in the serotonergic system which one of the best studied and understood transmitter systems. Both are critically involved in the organization of all behaviors and in the regulation of emotion and mood.

  • Features two new sections on serotonin systems interactions and serotonin in neurological disorders
  • Focuses on ionotropic and metabotropic 5-HT receptor involvement in behavior
  • Maps receptors and receptor signaling pathways to neurochemical and behavioral outcomes
  • Covers the interactions between serotonin, melatonin and kynurenine pathways

1. I. Introduction - p. 665 2. II. 5-HT synthesis, storage, release, uptake, and degradation - p. 665 3. III. 5-HT receptors - p. 680 4. IV. Summary and concluding remarks - p. 695 5. Chapter 39. Serotonin and schizophrenia - p. 711 6. Chapter 40. Serotonin neurobiology in cocaine use disorder - p. 745 7. I. Serotonin as a mechanistic target in cocaine use disorder - p. 745 8. II. Phasic and progressive cycle of cocaine use disorder - p. 747 9. III. Neurocircuitry in cocaine use disorder - p. 748 10. IV. Preclinical modeling of cycles of cocaine use disorder - p. 749 11. V. Risk vulnerability factors for cocaine use disorder - p. 753 12. VI. Serotonin neurotransmission and cocaine reward - p. 755 13. VII. Serotonin neurotransmission and cocaine cue reactivity - p. 766 14. VIII. Serotonin at the intersection of impulsivity and cocaine cue reactivity - p. 769 15. IX. Serotonergic therapeutics in cocaine use disorder - p. 773 16. X. Potential for serotonergic biomarkers in cocaine use disorder - p. 776 17. XI. Future directions and conclusions - p. 778 18. Chapter 41. The role of serotonin in alcohol use and abuse - p. 803 19. Chapter 42. The role of serotonin in nicotine abuse and addiction - p. 829 20. Chapter 43. Serotonin and serotonin receptors in hallucinogen action - p. 843 21. Chapter 44. The serotonergic system in obsessive-compulsive disorder - p. 865 22. Chapter 45. Peripheral and central serotonin in the regulation of glucose metabolism - p. 893 23. Chapter 46. Serotonin in cortical development: implications for autism spectrum disorder - p. 901 24. Chapter 47. Genetic, epigenetic, and environmental factors in serotonin-associated disease condition - p. 923 25. Chapter 48. Functional pharmacogenetics of serotonin receptors in psychiatric drug action - p. 941 26. Chapter 49. Classic psychedelics as therapeutics for psychiatric disorders - p. 959 27. Serotonin in neurological disorders - p. 966 28. Chapter 50. Serotonin in Parkinson's disease - p. 969 29. Chapter 51. Serotonin in seizures and epilepsy: a neurodevelopmental perspective - p. 981 30. Chapter 52. Serotonin and stroke - p. 989 31. Index - p. 1001

Descripcion
Descripción

Handbook of the Behavioral Neurobiology of Serotonin, Second Edition, builds on the success of the first edition by continuing to provide a detailed and comprehensive overview of the many facets of behavioral serotonin research. The text expands on the two key topics, behavioral control (sensory processing, ultrasonic vocalization, and melatonin and sleep control) and psychiatric disorders, including its role on psychostimulant abuse and addiction. The new edition includes two new sections on the serotonin systems interactions and the involvement of serotonin in neurological disorders and associated treatment.

Serotonin is a major neurotransmitters in the serotonergic system which one of the best studied and understood transmitter systems. Both are critically involved in the organization of all behaviors and in the regulation of emotion and mood.

  • Features two new sections on serotonin systems interactions and serotonin in neurological disorders
  • Focuses on ionotropic and metabotropic 5-HT receptor involvement in behavior
  • Maps receptors and receptor signaling pathways to neurochemical and behavioral outcomes
  • Covers the interactions between serotonin, melatonin and kynurenine pathways

1. I. Introduction - p. 665 2. II. 5-HT synthesis, storage, release, uptake, and degradation - p. 665 3. III. 5-HT receptors - p. 680 4. IV. Summary and concluding remarks - p. 695 5. Chapter 39. Serotonin and schizophrenia - p. 711 6. Chapter 40. Serotonin neurobiology in cocaine use disorder - p. 745 7. I. Serotonin as a mechanistic target in cocaine use disorder - p. 745 8. II. Phasic and progressive cycle of cocaine use disorder - p. 747 9. III. Neurocircuitry in cocaine use disorder - p. 748 10. IV. Preclinical modeling of cycles of cocaine use disorder - p. 749 11. V. Risk vulnerability factors for cocaine use disorder - p. 753 12. VI. Serotonin neurotransmission and cocaine reward - p. 755 13. VII. Serotonin neurotransmission and cocaine cue reactivity - p. 766 14. VIII. Serotonin at the intersection of impulsivity and cocaine cue reactivity - p. 769 15. IX. Serotonergic therapeutics in cocaine use disorder - p. 773 16. X. Potential for serotonergic biomarkers in cocaine use disorder - p. 776 17. XI. Future directions and conclusions - p. 778 18. Chapter 41. The role of serotonin in alcohol use and abuse - p. 803 19. Chapter 42. The role of serotonin in nicotine abuse and addiction - p. 829 20. Chapter 43. Serotonin and serotonin receptors in hallucinogen action - p. 843 21. Chapter 44. The serotonergic system in obsessive-compulsive disorder - p. 865 22. Chapter 45. Peripheral and central serotonin in the regulation of glucose metabolism - p. 893 23. Chapter 46. Serotonin in cortical development: implications for autism spectrum disorder - p. 901 24. Chapter 47. Genetic, epigenetic, and environmental factors in serotonin-associated disease condition - p. 923 25. Chapter 48. Functional pharmacogenetics of serotonin receptors in psychiatric drug action - p. 941 26. Chapter 49. Classic psychedelics as therapeutics for psychiatric disorders - p. 959 27. Serotonin in neurological disorders - p. 966 28. Chapter 50. Serotonin in Parkinson's disease - p. 969 29. Chapter 51. Serotonin in seizures and epilepsy: a neurodevelopmental perspective - p. 981 30. Chapter 52. Serotonin and stroke - p. 989 31. Index - p. 1001

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