Hemocompatibility of Biomaterials for Clinical Applications: Blood-Biomaterials Interactions summarizes the state-of-the-art on this important subject. The first part of the book reviews the latest research on blood composition and response, mechanisms of coagulation, test standards and methods. Next, the book assesses techniques for modifying biomaterial surfaces and developing coatings to improve hemocompatibility. In the final sections, users will find discussions on ways to improve the hemocompatibility of particular classes of biomaterials and a review of methods for improving medical devices.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xi 6. Part One: Fundamentals and testing methods for the hemocompatiblity of biomaterials - p. xiii 7. 1: Contact activation by the intrinsic pathway of blood plasma coagulation - p. xiii 8. 2: Mechanisms of blood coagulation in response to biomaterials: Extrinsic factors - p. 28 9. 3: Developing standards and test protocols for testing the hemocompatibility of biomaterials - p. 49 10. 4: Test methods for hemocompatibility of biomaterials - p. 76 11. Part Two: Improving the hemocompatibility of biomaterial surfaces - p. 104 12. 5: Analyzing biomaterial surfaces and blood-surface interactions - p. 104 13. 6: Surface analysis technique for assessing hemocompatibility of biomaterials - p. 117 14. 7: Coatings for biomaterials to improve hemocompatibility - p. 161 15. 8: Techniques for modifying biomaterials to improve hemocompatibility - p. 190 16. Part Three: Improving the hemocompatibility of types of biomaterial - p. 220 17. 9: Improving the hemocompatibility of biomedical polymers - p. 220 18. 10: Strategies to improve the hemocompatibility of biodegradable biomaterials - p. 252 19. 11: Surface treatment of metallic biomaterials in contact with blood to enhance hemocompatibility - p. 278 20. 12: Bioinspired thin film materials designed for blood contact - p. 326 21. 13: Improving the hemocompatibility of biomedical composites - p. 356 22. Part Four: Biomedical applications of hemocompatible biomaterials - p. 375 23. 14: Improving the hemocompatibility of stents - p. 375 24. 15: Improving the hemocompatibility of heart valves - p. 394 25. 16: Improving the hemocompatibility of catheters via NO release/generation - p. 429 26. Index - p. 457
Hemocompatibility of Biomaterials for Clinical Applications: Blood-Biomaterials Interactions summarizes the state-of-the-art on this important subject. The first part of the book reviews the latest research on blood composition and response, mechanisms of coagulation, test standards and methods. Next, the book assesses techniques for modifying biomaterial surfaces and developing coatings to improve hemocompatibility. In the final sections, users will find discussions on ways to improve the hemocompatibility of particular classes of biomaterials and a review of methods for improving medical devices.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xi 6. Part One: Fundamentals and testing methods for the hemocompatiblity of biomaterials - p. xiii 7. 1: Contact activation by the intrinsic pathway of blood plasma coagulation - p. xiii 8. 2: Mechanisms of blood coagulation in response to biomaterials: Extrinsic factors - p. 28 9. 3: Developing standards and test protocols for testing the hemocompatibility of biomaterials - p. 49 10. 4: Test methods for hemocompatibility of biomaterials - p. 76 11. Part Two: Improving the hemocompatibility of biomaterial surfaces - p. 104 12. 5: Analyzing biomaterial surfaces and blood-surface interactions - p. 104 13. 6: Surface analysis technique for assessing hemocompatibility of biomaterials - p. 117 14. 7: Coatings for biomaterials to improve hemocompatibility - p. 161 15. 8: Techniques for modifying biomaterials to improve hemocompatibility - p. 190 16. Part Three: Improving the hemocompatibility of types of biomaterial - p. 220 17. 9: Improving the hemocompatibility of biomedical polymers - p. 220 18. 10: Strategies to improve the hemocompatibility of biodegradable biomaterials - p. 252 19. 11: Surface treatment of metallic biomaterials in contact with blood to enhance hemocompatibility - p. 278 20. 12: Bioinspired thin film materials designed for blood contact - p. 326 21. 13: Improving the hemocompatibility of biomedical composites - p. 356 22. Part Four: Biomedical applications of hemocompatible biomaterials - p. 375 23. 14: Improving the hemocompatibility of stents - p. 375 24. 15: Improving the hemocompatibility of heart valves - p. 394 25. 16: Improving the hemocompatibility of catheters via NO release/generation - p. 429 26. Index - p. 457
