Prepare for Canadian nursing practice with a solid understanding of pathophysiology and disease! Huether and McCance's Understanding Pathophysiology, 2nd Canadian Edition covers the basic concepts of pathophysiology and disease processes from a Canadian perspective. Clear descriptions and vibrant illustrations make it easier to understand body systems and the mechanisms of disease, and online resources bring pathophysiology concepts to life. Developed for Canadian nursing students by educators Kelly Power-Kean, Stephanie Zettel, and Mohamed Toufic El-Hussein, this text prepares students for success on the Next Generation NCLEX®, CPNRE®, and REx-PN™ and also in clinical practice.
1. Introduction to Pathophysiology - p. xiii 2. Part One: Basic Concepts of Pathophysiology - p. 1 3. Unit 1: The Cell - p. 1a 4. 1. Cellular Biology - p. 1b 5. 2. Genes and Genetic Diseases - p. 38 6. 3. Epigenetics and Disease - p. 62 7. 4. Altered Cellular and Tissue Biology - p. 72 8. Chapter Outline - p. 72 9. Key Terms - p. 72 10. Cellular Adaptation - p. 73 11. Cellular Injury - p. 77 12. Manifestations of Cellular Injury: Accumulations - p. 95 13. Cellular Death - p. 100 14. Aging and Altered Cellular and Tissue Biology - p. 106 15. Somatic Death - p. 108 16. Did You Understand? - p. 109 17. References (Chapter 4) - p. 111.e1 18. 5. Fluids and Electrolytes, Acids and Bases - p. 112 19. Unit 2: Mechanisms of Self-Defence - p. 133 20. 6. Innate Immunity: Inflammation and Wound Healing - p. 133a 21. 7. Adaptive Immunity - p. 157 22. 8. Infection and Defects in Mechanisms of Defence - p. 176 23. Chapter Outline - p. 176 24. Key Terms - p. 176 25. Infection - p. 177 26. Deficiencies in Immunity - p. 191 27. Hypersensitivity: Allergy, Autoimmunity, and Alloimmunity - p. 199 28. Did You Understand? - p. 213 29. References (Chapter 8) - p. 214.e1 30. 9. Stress and Disease - p. 215 31. Unit 3: Cellular Proliferation: Cancer - p. 233 32. 10. Biology of Cancer - p. 233a 33. 11. Cancer Epidemiology - p. 266 34. 12. Cancer in Children and Adolescents - p. 294 35. Part Two: Body Systems and Diseases - p. 299 36. Unit 4: The Neurological System - p. 299a 37. 13. Structure and Function of the Neurological System - p. 299b 38. 14. Pain, Temperature, Sleep, and Sensory Function - p. 328 39. 15. Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function - p. 351 40. 16. Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction - p. 382 41. 17. Developmental Alterations of Neurological Function - p. 411 42. Unit 5: The Endocrine System - p. 426 43. 18. Mechanisms of Hormonal Regulation - p. 426a 44. 19. Alterations of Hormonal Regulation - p. 447 45. Unit 6: The Hematological System - p. 477 46. 20. Structure and Function of the Hematological System - p. 477a 47. 21. Alterations of Hematological Function - p. 500 48. Chapter Outline - p. 500 49. Key Terms - p. 500 50. Alterations of Erythrocyte Function - p. 501 51. Myeloproliferative Red Blood Cell Disorders - p. 507 52. Alterations of Leukocyte Function - p. 510 53. Alterations of Lymphoid Function - p. 518 54. Alterations of Splenic Function - p. 524 55. Hemorrhagic Disorders and Alterations of Platelets and Coagulation - p. 526 56. Did You Understand? - p. 534 57. References (Chapter 21) - p. 536.e1 58. 22. Developmental Alterations of Hematological Function - p. 537 59. Unit 7: The Cardiovascular and Lymphatic Systems - p. 551 60. 23. Structure and Function of the Cardiovascular and Lymphatic Systems - p. 551a 61. 24. Alterations of Cardiovascular Function - p. 579 62. Chapter Outline - p. 579 63. Key Terms - p. 579 64. Diseases of the Veins - p. 580 65. Diseases of the Arteries - p. 581 66. Disorders of the Heart Wall - p. 606 67. Manifestations of Heart Disease - p. 616 68. Shock - p. 621 69. Did You Understand? - p. 634 70. References (Chapter 24) - p. 636.e1 71. 25. Developmental Alterations of Cardiovascular Function - p. 637 72. Unit 8: The Pulmonary System - p. 653 73. 26. Structure and Function of the Pulmonary System - p. 653a 74. 27. Alterations of Pulmonary Function - p. 669 75. Chapter Outline - p. 669 76. Key Terms - p. 669 77. Clinical Manifestations of Pulmonary Alterations - p. 670 78. Disorders of the Chest Wall and Pleura - p. 673 79. Pulmonary Disorders - p. 675 80. Did You Understand? - p. 700 81. References (Chapter 27) - p. 700.e1 82. 28. Developmental Alterations of Pulmonary Function - p. 701 83. Unit 9: The Renal and Urological Systems - p. 713 84. 29. Structure and Function of the Renal and Urological Systems - p. 713a 85. 30. Alterations of Renal and Urinary Tract Function - p. 730 86. 31. Developmental Alterations of Renal and Urinary Tract Function - p. 756 87. Unit 10: The Reproductive Systems - p. 763 88. 32. Structure and Function of the Reproductive Systems - p. 763a 89. 33. Alterations of the Female Reproductive System - p. 785 90. Chapter Outline - p. 785 91. Key Terms - p. 785 92. Abnormalities of the Female Reproductive Tract - p. 786 93. Alterations of Sexual Maturation - p. 786 94. Disorders of the Female Reproductive System - p. 787 95. Disorders of the Female Breast - p. 812 96. Did You Understand? - p. 830 97. References (Chapter 33) - p. 831.e1 98. 34. Alterations of the Male Reproductive System - p. 832 99. Unit 11: The Digestive System - p. 861 100. 35. Structure and Function of the Digestive System - p. 861a 101. 36. Alterations of Digestive Function - p. 882 102. Chapter Outline - p. 882 103. Key Terms - p. 882 104. Disorders of the Gastro-Intestinal Tract - p. 883 105. Disorders of the Accessory Organs of Digestion - p. 905 106. Cancer of the Digestive System - p. 917 107. Did You Understand? - p. 924 108. References (Chapter 36) - p. 926.e1 109. 37. Developmental Alterations of Digestive Function - p. 927 110. Unit 12: The Musculoskeletal and Integumentary Systems - p. 942 111. 38. Structure and Function of the Musculoskeletal System - p. 942a 112. 39. Alterations of Musculoskeletal Function - p. 964 113. Chapter Outline - p. 964 114. Key Terms - p. 964 115. Musculoskeletal Injuries - p. 965 116. Disorders of Bones - p. 973 117. Disorders of Joints - p. 982 118. Disorders of Skeletal Muscle - p. 994 119. Musculoskeletal Tumours - p. 1000 120. Did you understand? - p. 1005 121. References (Chapter 39) - p. 1006.e1 122. 40. Developmental Alterations of Musculoskeletal Function - p. 1007 123. 41. Structure, Function, and Disorders of the Integument - p. 1021 124. 42. Developmental Alterations of the Integument - p. 1053 125. Appendix - p. 1064 126. Index - p. 1081 127. Prefixes and Suffixes used in Medical Terminology - p. 1128 128. Word Roots Commonly used in Medical Terminology - p. IBC1
Prepare for Canadian nursing practice with a solid understanding of pathophysiology and disease! Huether and McCance's Understanding Pathophysiology, 2nd Canadian Edition covers the basic concepts of pathophysiology and disease processes from a Canadian perspective. Clear descriptions and vibrant illustrations make it easier to understand body systems and the mechanisms of disease, and online resources bring pathophysiology concepts to life. Developed for Canadian nursing students by educators Kelly Power-Kean, Stephanie Zettel, and Mohamed Toufic El-Hussein, this text prepares students for success on the Next Generation NCLEX®, CPNRE®, and REx-PN™ and also in clinical practice.
1. Introduction to Pathophysiology - p. xiii 2. Part One: Basic Concepts of Pathophysiology - p. 1 3. Unit 1: The Cell - p. 1a 4. 1. Cellular Biology - p. 1b 5. 2. Genes and Genetic Diseases - p. 38 6. 3. Epigenetics and Disease - p. 62 7. 4. Altered Cellular and Tissue Biology - p. 72 8. Chapter Outline - p. 72 9. Key Terms - p. 72 10. Cellular Adaptation - p. 73 11. Cellular Injury - p. 77 12. Manifestations of Cellular Injury: Accumulations - p. 95 13. Cellular Death - p. 100 14. Aging and Altered Cellular and Tissue Biology - p. 106 15. Somatic Death - p. 108 16. Did You Understand? - p. 109 17. References (Chapter 4) - p. 111.e1 18. 5. Fluids and Electrolytes, Acids and Bases - p. 112 19. Unit 2: Mechanisms of Self-Defence - p. 133 20. 6. Innate Immunity: Inflammation and Wound Healing - p. 133a 21. 7. Adaptive Immunity - p. 157 22. 8. Infection and Defects in Mechanisms of Defence - p. 176 23. Chapter Outline - p. 176 24. Key Terms - p. 176 25. Infection - p. 177 26. Deficiencies in Immunity - p. 191 27. Hypersensitivity: Allergy, Autoimmunity, and Alloimmunity - p. 199 28. Did You Understand? - p. 213 29. References (Chapter 8) - p. 214.e1 30. 9. Stress and Disease - p. 215 31. Unit 3: Cellular Proliferation: Cancer - p. 233 32. 10. Biology of Cancer - p. 233a 33. 11. Cancer Epidemiology - p. 266 34. 12. Cancer in Children and Adolescents - p. 294 35. Part Two: Body Systems and Diseases - p. 299 36. Unit 4: The Neurological System - p. 299a 37. 13. Structure and Function of the Neurological System - p. 299b 38. 14. Pain, Temperature, Sleep, and Sensory Function - p. 328 39. 15. Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function - p. 351 40. 16. Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction - p. 382 41. 17. Developmental Alterations of Neurological Function - p. 411 42. Unit 5: The Endocrine System - p. 426 43. 18. Mechanisms of Hormonal Regulation - p. 426a 44. 19. Alterations of Hormonal Regulation - p. 447 45. Unit 6: The Hematological System - p. 477 46. 20. Structure and Function of the Hematological System - p. 477a 47. 21. Alterations of Hematological Function - p. 500 48. Chapter Outline - p. 500 49. Key Terms - p. 500 50. Alterations of Erythrocyte Function - p. 501 51. Myeloproliferative Red Blood Cell Disorders - p. 507 52. Alterations of Leukocyte Function - p. 510 53. Alterations of Lymphoid Function - p. 518 54. Alterations of Splenic Function - p. 524 55. Hemorrhagic Disorders and Alterations of Platelets and Coagulation - p. 526 56. Did You Understand? - p. 534 57. References (Chapter 21) - p. 536.e1 58. 22. Developmental Alterations of Hematological Function - p. 537 59. Unit 7: The Cardiovascular and Lymphatic Systems - p. 551 60. 23. Structure and Function of the Cardiovascular and Lymphatic Systems - p. 551a 61. 24. Alterations of Cardiovascular Function - p. 579 62. Chapter Outline - p. 579 63. Key Terms - p. 579 64. Diseases of the Veins - p. 580 65. Diseases of the Arteries - p. 581 66. Disorders of the Heart Wall - p. 606 67. Manifestations of Heart Disease - p. 616 68. Shock - p. 621 69. Did You Understand? - p. 634 70. References (Chapter 24) - p. 636.e1 71. 25. Developmental Alterations of Cardiovascular Function - p. 637 72. Unit 8: The Pulmonary System - p. 653 73. 26. Structure and Function of the Pulmonary System - p. 653a 74. 27. Alterations of Pulmonary Function - p. 669 75. Chapter Outline - p. 669 76. Key Terms - p. 669 77. Clinical Manifestations of Pulmonary Alterations - p. 670 78. Disorders of the Chest Wall and Pleura - p. 673 79. Pulmonary Disorders - p. 675 80. Did You Understand? - p. 700 81. References (Chapter 27) - p. 700.e1 82. 28. Developmental Alterations of Pulmonary Function - p. 701 83. Unit 9: The Renal and Urological Systems - p. 713 84. 29. Structure and Function of the Renal and Urological Systems - p. 713a 85. 30. Alterations of Renal and Urinary Tract Function - p. 730 86. 31. Developmental Alterations of Renal and Urinary Tract Function - p. 756 87. Unit 10: The Reproductive Systems - p. 763 88. 32. Structure and Function of the Reproductive Systems - p. 763a 89. 33. Alterations of the Female Reproductive System - p. 785 90. Chapter Outline - p. 785 91. Key Terms - p. 785 92. Abnormalities of the Female Reproductive Tract - p. 786 93. Alterations of Sexual Maturation - p. 786 94. Disorders of the Female Reproductive System - p. 787 95. Disorders of the Female Breast - p. 812 96. Did You Understand? - p. 830 97. References (Chapter 33) - p. 831.e1 98. 34. Alterations of the Male Reproductive System - p. 832 99. Unit 11: The Digestive System - p. 861 100. 35. Structure and Function of the Digestive System - p. 861a 101. 36. Alterations of Digestive Function - p. 882 102. Chapter Outline - p. 882 103. Key Terms - p. 882 104. Disorders of the Gastro-Intestinal Tract - p. 883 105. Disorders of the Accessory Organs of Digestion - p. 905 106. Cancer of the Digestive System - p. 917 107. Did You Understand? - p. 924 108. References (Chapter 36) - p. 926.e1 109. 37. Developmental Alterations of Digestive Function - p. 927 110. Unit 12: The Musculoskeletal and Integumentary Systems - p. 942 111. 38. Structure and Function of the Musculoskeletal System - p. 942a 112. 39. Alterations of Musculoskeletal Function - p. 964 113. Chapter Outline - p. 964 114. Key Terms - p. 964 115. Musculoskeletal Injuries - p. 965 116. Disorders of Bones - p. 973 117. Disorders of Joints - p. 982 118. Disorders of Skeletal Muscle - p. 994 119. Musculoskeletal Tumours - p. 1000 120. Did you understand? - p. 1005 121. References (Chapter 39) - p. 1006.e1 122. 40. Developmental Alterations of Musculoskeletal Function - p. 1007 123. 41. Structure, Function, and Disorders of the Integument - p. 1021 124. 42. Developmental Alterations of the Integument - p. 1053 125. Appendix - p. 1064 126. Index - p. 1081 127. Prefixes and Suffixes used in Medical Terminology - p. 1128 128. Word Roots Commonly used in Medical Terminology - p. IBC1
