Human Reproductive and Prenatal Genetics presents the latest material from a detailed molecular, cellular and translational perspective. Considering its timeliness and potential international impact, this all-inclusive and authoritative work is ideal for researchers, students, and clinicians worldwide. Currently, there are no comprehensive books covering the field of human reproductive and prenatal genetics. As such, this book aims to be among the largest and most useful references available.
Named a Highly Commended book in the Basic and Clinical Sciences by the British Medical Association.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xi 6. Part I: Reproductive Tract Development and Gametogenesis - p. xv 7. Chapter 1: Developmental Genetics of the Male Reproductive System - p. xv 8. Chapter 2: Genetics and Genomics of Early Gonad Development - p. 24 9. Chapter 3: Genetics of Meiotic Chromosome Dynamics and Fertility - p. 50 10. Chapter 4: Effects of Aging on Sperm Chromatin - p. 84 11. Chapter 5: In Vitro Spermatogenesis From Pluripotent Stem Cells - p. 103 12. Chapter 6: Developmental Genetics of the Female Reproductive Tract - p. 128 13. Chapter 7: The Molecular Genetics of Oogenesis - p. 153 14. Chapter 8: Epigenetic Control of Oocyte Development - p. 172 15. Chapter 9: RNA Binding Protein Networks and Translational Regulation in Oocytes - p. 192 16. Chapter 10: Translational Regulation of Gene Expression During Oogenesis and Preimplantation Embryo Development - p. 220 17. Chapter 11: MicroRNAs in Gametes and Preimplantation Embryos: Clinical Implications - p. 239 18. Part II: Embryo Implantation, Placenta Development and Pregnancy - p. 268 19. Chapter 12: Transcriptomics of the Human Endometrium and Embryo Implantation - p. 268 20. Chapter 13: Epigenetic Modifications in the Human Placenta - p. 291 21. Chapter 14: microRNAs in Pregnancy: Implications for Basic Research and Clinical Management - p. 311 22. Chapter 15: Genetics and Genomics of Preterm Birth - p. 333 23. Chapter 16: The Intergenerational Effects on Fetal Programming - p. 359 24. Part III: Infertility and Assisted Reproductive Technology - p. 379 25. Chapter 17: Genetic Testing in Male Infertility - p. 379 26. Chapter 18: Genetics and Genomics of Endometriosis - p. 398 27. Chapter 19: Genetics and Genomics of Primary Ovarian Insufficiency - p. 426 28. Chapter 20: Genetics of Polycystic Ovary Syndrome - p. 445 29. Chapter 21: Genetics and Genomics of Recurrent Pregnancy Loss - p. 461 30. Chapter 22: Human Genetics and Assisted Reproduction in Endometriosis - p. 493 31. Chapter 23: Uterine Transplantation - p. 514 32. Part IV: Preimplantation/Prenatal Genetic Diagnosis and Screening - p. 525 33. Chapter 24: Epidemiology and Genetics of Human Aneuploidy - p. 525 34. Chapter 25: Next-Generation Sequencing for Gene Panels and Clinical Exomes - p. 551 35. Chapter 26: Chromosomal Microarrays and Exome Sequencing for Diagnosis of Fetal Abnormalities - p. 574 36. Chapter 27: Noninvasive Prenatal Testing for Genetic Diseases - p. 595 37. Chapter 28: Noninvasive Prenatal Testing by Cell-Free DNA: Technology, Biology, Clinical Utility, and Limitations - p. 625 38. Chapter 29: Prenatal Diagnosis and Treatment of Genetic Steroid Disorders - p. 652 39. Chapter 30: Application of Gene-Editing Technologies in Embryos and Their Potential for Gene Therapy - p. 658 40. Index - p. 677
Human Reproductive and Prenatal Genetics presents the latest material from a detailed molecular, cellular and translational perspective. Considering its timeliness and potential international impact, this all-inclusive and authoritative work is ideal for researchers, students, and clinicians worldwide. Currently, there are no comprehensive books covering the field of human reproductive and prenatal genetics. As such, this book aims to be among the largest and most useful references available.
Named a Highly Commended book in the Basic and Clinical Sciences by the British Medical Association.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xi 6. Part I: Reproductive Tract Development and Gametogenesis - p. xv 7. Chapter 1: Developmental Genetics of the Male Reproductive System - p. xv 8. Chapter 2: Genetics and Genomics of Early Gonad Development - p. 24 9. Chapter 3: Genetics of Meiotic Chromosome Dynamics and Fertility - p. 50 10. Chapter 4: Effects of Aging on Sperm Chromatin - p. 84 11. Chapter 5: In Vitro Spermatogenesis From Pluripotent Stem Cells - p. 103 12. Chapter 6: Developmental Genetics of the Female Reproductive Tract - p. 128 13. Chapter 7: The Molecular Genetics of Oogenesis - p. 153 14. Chapter 8: Epigenetic Control of Oocyte Development - p. 172 15. Chapter 9: RNA Binding Protein Networks and Translational Regulation in Oocytes - p. 192 16. Chapter 10: Translational Regulation of Gene Expression During Oogenesis and Preimplantation Embryo Development - p. 220 17. Chapter 11: MicroRNAs in Gametes and Preimplantation Embryos: Clinical Implications - p. 239 18. Part II: Embryo Implantation, Placenta Development and Pregnancy - p. 268 19. Chapter 12: Transcriptomics of the Human Endometrium and Embryo Implantation - p. 268 20. Chapter 13: Epigenetic Modifications in the Human Placenta - p. 291 21. Chapter 14: microRNAs in Pregnancy: Implications for Basic Research and Clinical Management - p. 311 22. Chapter 15: Genetics and Genomics of Preterm Birth - p. 333 23. Chapter 16: The Intergenerational Effects on Fetal Programming - p. 359 24. Part III: Infertility and Assisted Reproductive Technology - p. 379 25. Chapter 17: Genetic Testing in Male Infertility - p. 379 26. Chapter 18: Genetics and Genomics of Endometriosis - p. 398 27. Chapter 19: Genetics and Genomics of Primary Ovarian Insufficiency - p. 426 28. Chapter 20: Genetics of Polycystic Ovary Syndrome - p. 445 29. Chapter 21: Genetics and Genomics of Recurrent Pregnancy Loss - p. 461 30. Chapter 22: Human Genetics and Assisted Reproduction in Endometriosis - p. 493 31. Chapter 23: Uterine Transplantation - p. 514 32. Part IV: Preimplantation/Prenatal Genetic Diagnosis and Screening - p. 525 33. Chapter 24: Epidemiology and Genetics of Human Aneuploidy - p. 525 34. Chapter 25: Next-Generation Sequencing for Gene Panels and Clinical Exomes - p. 551 35. Chapter 26: Chromosomal Microarrays and Exome Sequencing for Diagnosis of Fetal Abnormalities - p. 574 36. Chapter 27: Noninvasive Prenatal Testing for Genetic Diseases - p. 595 37. Chapter 28: Noninvasive Prenatal Testing by Cell-Free DNA: Technology, Biology, Clinical Utility, and Limitations - p. 625 38. Chapter 29: Prenatal Diagnosis and Treatment of Genetic Steroid Disorders - p. 652 39. Chapter 30: Application of Gene-Editing Technologies in Embryos and Their Potential for Gene Therapy - p. 658 40. Index - p. 677
