Imidazole-Based Drug Discovery covers all categories of imidazole and its derivatives, synthesis, pharmacological applications and drug-based studies. Imidazole scaffolds act as a channel between organic synthesis and medicinal chemistry and compel researchers to explore new drug candidates. This book provides detailed coverage of several greener synthetic protocols and pharmacological applications of imidazole derivatives that are useful to researchers working on designing more promising clinical lead compounds with this scaffold. It also includes information on past decades of research on the synthesis and biological applications of imidazole derivatives.
This is an ideal resource for researchers in organic chemistry both in academic and industrial settings, as well as postgraduates in chemistry and medicinal chemistry.
1. Chapter 1. Imidazole and its derivatives: Introduction and synthetic aspects - p. 1 2. Chapter 2. Biological profile of imidazole-based compounds as anticancer agents - p. 35 3. Chapter 3. Recent advancements on imidazole containing heterocycles as antitubercular agents - p. 133 4. Chapter 4. Imidazole derivatives: Impact and prospects in antiviral drug discovery - p. 167 5. Chapter 5. Imidazole heterocycles: Therapeutically potent lead compounds as antimicrobials - p. 195 6. Chapter 6. Imidazole containing heterocycles as antioxidants - p. 285 7. Chapter 7. Miscellaneous biological activity profile of imidazole-based compounds: An aspirational goal for medicinal chemistry - p. 291 8. Chapter 8. Imidazole-based drugs and drug discovery: Present and future perspectives - p. 325 9. Index - p. 349
Imidazole-Based Drug Discovery covers all categories of imidazole and its derivatives, synthesis, pharmacological applications and drug-based studies. Imidazole scaffolds act as a channel between organic synthesis and medicinal chemistry and compel researchers to explore new drug candidates. This book provides detailed coverage of several greener synthetic protocols and pharmacological applications of imidazole derivatives that are useful to researchers working on designing more promising clinical lead compounds with this scaffold. It also includes information on past decades of research on the synthesis and biological applications of imidazole derivatives.
This is an ideal resource for researchers in organic chemistry both in academic and industrial settings, as well as postgraduates in chemistry and medicinal chemistry.
1. Chapter 1. Imidazole and its derivatives: Introduction and synthetic aspects - p. 1 2. Chapter 2. Biological profile of imidazole-based compounds as anticancer agents - p. 35 3. Chapter 3. Recent advancements on imidazole containing heterocycles as antitubercular agents - p. 133 4. Chapter 4. Imidazole derivatives: Impact and prospects in antiviral drug discovery - p. 167 5. Chapter 5. Imidazole heterocycles: Therapeutically potent lead compounds as antimicrobials - p. 195 6. Chapter 6. Imidazole containing heterocycles as antioxidants - p. 285 7. Chapter 7. Miscellaneous biological activity profile of imidazole-based compounds: An aspirational goal for medicinal chemistry - p. 291 8. Chapter 8. Imidazole-based drugs and drug discovery: Present and future perspectives - p. 325 9. Index - p. 349
