Immune Therapy for Pancreatic and Colon Cancer expands the knowledge on pathways, immune modulators, immune check points, and monoclonal antibodies that can lead to appropriate cancer treatment. With a strong focus on the development of immune therapies to improve the survival rates of pancreatic and colon cancer, this book also shows the latest trends in immune targeted approaches for cancer treatment. Sections describe the role of and the immune response to pancreatic and colon cancer, gives insights to past and current immunotherapies, including metabolic reprogramming, immune blockade therapy and immune modulation.
This book is a valuable resource for health professionals, scientists and researchers, students, and all those who wish to broaden their knowledge of the advances in immunotherapy in pancreatic and colon cancer, inspire them and guide their design of novel experimental projects and translational studies.
1. Chapter 1 Introduction to colon and pancreatic cancers - p. 2 2. Chapter 2 An overview of imaging in pancreatic cancer - p. 24 3. Chapter 3 Colorectal cancer: Understanding the pathophysiology, screening options and treatment approaches - p. 45 4. Chapter 4 Tumor microenvironment of colorectal cancer - p. 67 5. Chapter 5 Role of PD-1 as an immunotherapeutic target in GI cancers - p. 86 6. Chapter 6 Immunotherapy in colorectal cancer: Understanding the PD-1 and CTLA-4 targeted therapies for MSI-H/dMMR tumors - p. 97 7. Chapter 7 Single-cell analysis of colon cancer: Novel insight into drug resistance and immunotherapy - p. 106 8. Chapter 8 Delivery strategies of immunotherapies in the treatment of colorectal cancer - p. 114 9. Chapter 9 Therapeutic role of immune cells against colon cancer - p. 127 10. Chapter 10 The potential of biosimilars in the treatment of colorectal cancer: Focus on bevacizumab - p. 147 11. Chapter 11 Understanding colorectal cancer, screening, and treatment - p. 168 12. Chapter 12 Challenges in immunotherapy for PDAC: Overcoming immune resistance and enhancing treatment strategies - p. 191 13. Chapter 13 Unveiling the orchestration of T-cell dynamics: A comprehensive examination of their crucial role in revolutionizing immunotherapy for pancreatic and colon cancers - p. 200 14. Chapter 14 Role of T-cells in immunotherapy of pancreatic and colon cancers - p. 234 15. Chapter 15 Role of platelets in immunomodulation in pancreatic and colorectal cancers - p. 246 16. Chapter 16 The role of circulating tumor cells in the immunotherapy of pancreatic and colon cancers - p. 263 17. Chapter 17 Vaccine-based immunotherapy for pancreatic and colon cancers - p. 291 18. Chapter 18 Overcoming immunotherapeutic drug resistance in pancreatic and colon cancers - p. 305 19. Chapter 19 Metabolic programming of pancreatic and colon cancer - p. 326 20. Chapter 20 Managing adverse effects of novel immunotherapies in pancreatic and colon cancers - p. 342 21. Chapter 21 Expanding role of immunotherapeutics in colon and pancreatic cancers and managing their adverse effects - p. 363 22. Chapter 22 The role of monoclonal antibodies in the treatment of pancreatic and colon cancers - p. 389 23. Chapter 23 Expanding roles of microRNAs in colorectal cancer in the era of immunotherapy - p. 414 24. Chapter 24 Machine learning approaches for colorectal cancer risk prediction and stratification - p. 429 25. Chapter 25 Immune checkpoint inhibitors-associated cardiovascular toxicity in cancer therapy - p. 456 26. Chapter 26 Lifestyle, nutrition, and risk of pancreatic and colon cancers - p. 467 27. Index - p. 483
Immune Therapy for Pancreatic and Colon Cancer expands the knowledge on pathways, immune modulators, immune check points, and monoclonal antibodies that can lead to appropriate cancer treatment. With a strong focus on the development of immune therapies to improve the survival rates of pancreatic and colon cancer, this book also shows the latest trends in immune targeted approaches for cancer treatment. Sections describe the role of and the immune response to pancreatic and colon cancer, gives insights to past and current immunotherapies, including metabolic reprogramming, immune blockade therapy and immune modulation.
This book is a valuable resource for health professionals, scientists and researchers, students, and all those who wish to broaden their knowledge of the advances in immunotherapy in pancreatic and colon cancer, inspire them and guide their design of novel experimental projects and translational studies.
1. Chapter 1 Introduction to colon and pancreatic cancers - p. 2 2. Chapter 2 An overview of imaging in pancreatic cancer - p. 24 3. Chapter 3 Colorectal cancer: Understanding the pathophysiology, screening options and treatment approaches - p. 45 4. Chapter 4 Tumor microenvironment of colorectal cancer - p. 67 5. Chapter 5 Role of PD-1 as an immunotherapeutic target in GI cancers - p. 86 6. Chapter 6 Immunotherapy in colorectal cancer: Understanding the PD-1 and CTLA-4 targeted therapies for MSI-H/dMMR tumors - p. 97 7. Chapter 7 Single-cell analysis of colon cancer: Novel insight into drug resistance and immunotherapy - p. 106 8. Chapter 8 Delivery strategies of immunotherapies in the treatment of colorectal cancer - p. 114 9. Chapter 9 Therapeutic role of immune cells against colon cancer - p. 127 10. Chapter 10 The potential of biosimilars in the treatment of colorectal cancer: Focus on bevacizumab - p. 147 11. Chapter 11 Understanding colorectal cancer, screening, and treatment - p. 168 12. Chapter 12 Challenges in immunotherapy for PDAC: Overcoming immune resistance and enhancing treatment strategies - p. 191 13. Chapter 13 Unveiling the orchestration of T-cell dynamics: A comprehensive examination of their crucial role in revolutionizing immunotherapy for pancreatic and colon cancers - p. 200 14. Chapter 14 Role of T-cells in immunotherapy of pancreatic and colon cancers - p. 234 15. Chapter 15 Role of platelets in immunomodulation in pancreatic and colorectal cancers - p. 246 16. Chapter 16 The role of circulating tumor cells in the immunotherapy of pancreatic and colon cancers - p. 263 17. Chapter 17 Vaccine-based immunotherapy for pancreatic and colon cancers - p. 291 18. Chapter 18 Overcoming immunotherapeutic drug resistance in pancreatic and colon cancers - p. 305 19. Chapter 19 Metabolic programming of pancreatic and colon cancer - p. 326 20. Chapter 20 Managing adverse effects of novel immunotherapies in pancreatic and colon cancers - p. 342 21. Chapter 21 Expanding role of immunotherapeutics in colon and pancreatic cancers and managing their adverse effects - p. 363 22. Chapter 22 The role of monoclonal antibodies in the treatment of pancreatic and colon cancers - p. 389 23. Chapter 23 Expanding roles of microRNAs in colorectal cancer in the era of immunotherapy - p. 414 24. Chapter 24 Machine learning approaches for colorectal cancer risk prediction and stratification - p. 429 25. Chapter 25 Immune checkpoint inhibitors-associated cardiovascular toxicity in cancer therapy - p. 456 26. Chapter 26 Lifestyle, nutrition, and risk of pancreatic and colon cancers - p. 467 27. Index - p. 483
