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This issue of Orthopaedic Clinics will focus on infection. This issue will include articles on: Charcot Arthropathy versus Osteomyelitis: Evaluation and Management; Physical function, and physical activity in obese adults after total knee arthroplasty; DVT and PE Considerations in Orthopaedic Surgery; The Impact of Negative Pressure Wound Therapy on Orthopaedic Infection; Role of Systemic and Local Antibiotics in the Treatment of Open Fractures; Acute Hematogenous Osteomyelitis in Children; and many more!

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. CME Accreditation Page - p. iii 6. Editorial Board - p. v 7. Contributors - p. vii 8. Forthcoming Issues - p. xv 9. Preface - p. xvii 10. Adult Reconstruction - p. xvii 11. Effect of Tranexamic Acid on Transfusion Rates Following Total Joint Arthroplasty: A Cost and Comparative Effectiveness Analysis - p. 109 12. Physical Function and Physical Activity in Obese Adults After Total Knee Arthroplasty - p. 117 13. Deep Vein Thrombosis and Pulmonary Embolism Considerations in Orthopedic Surgery - p. 127 14. Trauma - p. 135 15. Role of Systemic and Local Antibiotics in the Treatment of Open Fractures - p. 137 16. The Antibiotic Nail in the Treatment of Long Bone Infection: Technique and Results - p. 155 17. The Impact of Negative Pressure Wound Therapy on Orthopaedic Infection - p. 167 18. Pediatrics - p. 179 19. Double-Edged Sword: Musculoskeletal Infection Provoked Acute Phase Response in Children - p. 181 20. Acute Hematogenous Osteomyelitis in Children: Pathogenesis, Diagnosis, and Treatment - p. 199 21. Pediatric Septic Arthritis - p. 209 22. Upper Extremity - p. 216 23. Flexor Tenosynovitis - p. 217 24. Atypical Hand Infections - p. 229 25. Foot and Ankle - p. 240 26. Charcot Arthropathy Versus Osteomyelitis: Evaluation and Management - p. 241 27. Posttraumatic Reconstruction of the Foot and Ankle in the Face of Active Infection - p. 249 28. Index - p. 259

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This issue of Orthopaedic Clinics will focus on infection. This issue will include articles on: Charcot Arthropathy versus Osteomyelitis: Evaluation and Management; Physical function, and physical activity in obese adults after total knee arthroplasty; DVT and PE Considerations in Orthopaedic Surgery; The Impact of Negative Pressure Wound Therapy on Orthopaedic Infection; Role of Systemic and Local Antibiotics in the Treatment of Open Fractures; Acute Hematogenous Osteomyelitis in Children; and many more!

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. CME Accreditation Page - p. iii 6. Editorial Board - p. v 7. Contributors - p. vii 8. Forthcoming Issues - p. xv 9. Preface - p. xvii 10. Adult Reconstruction - p. xvii 11. Effect of Tranexamic Acid on Transfusion Rates Following Total Joint Arthroplasty: A Cost and Comparative Effectiveness Analysis - p. 109 12. Physical Function and Physical Activity in Obese Adults After Total Knee Arthroplasty - p. 117 13. Deep Vein Thrombosis and Pulmonary Embolism Considerations in Orthopedic Surgery - p. 127 14. Trauma - p. 135 15. Role of Systemic and Local Antibiotics in the Treatment of Open Fractures - p. 137 16. The Antibiotic Nail in the Treatment of Long Bone Infection: Technique and Results - p. 155 17. The Impact of Negative Pressure Wound Therapy on Orthopaedic Infection - p. 167 18. Pediatrics - p. 179 19. Double-Edged Sword: Musculoskeletal Infection Provoked Acute Phase Response in Children - p. 181 20. Acute Hematogenous Osteomyelitis in Children: Pathogenesis, Diagnosis, and Treatment - p. 199 21. Pediatric Septic Arthritis - p. 209 22. Upper Extremity - p. 216 23. Flexor Tenosynovitis - p. 217 24. Atypical Hand Infections - p. 229 25. Foot and Ankle - p. 240 26. Charcot Arthropathy Versus Osteomyelitis: Evaluation and Management - p. 241 27. Posttraumatic Reconstruction of the Foot and Ankle in the Face of Active Infection - p. 249 28. Index - p. 259

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