The chemical industry changes and becomes more and more integrated worldwide. This creates a need for information exchange that includes not only the principles of operation but also the transfer of practical knowledge.
Integration and Optimization of Unit Operations provides up-to-date and practical information on chemical unit operations from the R&D stage to scale-up and demonstration to commercialization and optimization. A global collection of industry experts systematically discuss all innovation stages, complex processes with different unit operations, including solids processing and recycle flows, and the importance of integrated process validation. The book addresses the needs of engineers who want to increase their skill levels in various disciplines so that they are able to develop, commercialize and optimize processes. After reading this book, you will be able to acquire new skills and knowledge to collaborate across disciplines and develop creative solutions.
1. 2.1: Introduction - p. 13 2. 2.2: Microbiology and biochemistry basics - p. 13 3. 2.3: Fermentation media and environment - p. 21 4. 2.4: Growth kinetics and substrate utilization - p. 24 5. 2.5: From vial to production fermenter - p. 27 6. 2.6: Oxygen transfer and utilization - p. 29 7. 2.7: Mixing in aerobic fermentation vessels - p. 37 8. 2.8: Sterilization - p. 43 9. 2.9: Heat generation - p. 56 10. 2.10: Scale-up - p. 60 11. Chapter 3 Fermentation and downstream processing: Part 2 - p. 69 12. Chapter 4 Liquid filtration - p. 113 13. Chapter 5 Cake-building filter technologies - p. 125 14. Chapter 6 Centrifugation - p. 133 15. Chapter 7 Dryers - p. 145 16. Chapter 8 Pressure filter dryer - p. 177 17. Chapter 9 Process automation systems - p. 191 18. Chapter 10 Process automation life cycles - p. 219 19. Chapter 11 Process automation platforms - p. 239 20. Chapter 12 Mixing and blending - p. 249 21. Chapter 13 Process development and integration by mathematical modeling and simulation tools - p. 273 22. Chapter 14 Process safety - p. 293 23. Chapter 15 Process commissioning - p. 307 24. Chapter 16 Holistic process integration and optimization: Large-scale hybrid process applications - p. 317 25. Chapter 17 From idea to 1 million ton year commercial plant - p. 339 26. Chapter 18 Scale-up challenges: Examples from refining and catalysis - p. 345 27. Chapter 19 Scale-up challenges: Wastewater - p. 351 28. Chapter 20 Hemp/biomass process steps - p. 355 29. Chapter 21 Techno-economic analyses - p. 373 30. Chapter 22 Project management - p. 413 31. Chapter 23 Decommissioning - p. 433 32. Index - p. 437
The chemical industry changes and becomes more and more integrated worldwide. This creates a need for information exchange that includes not only the principles of operation but also the transfer of practical knowledge.
Integration and Optimization of Unit Operations provides up-to-date and practical information on chemical unit operations from the R&D stage to scale-up and demonstration to commercialization and optimization. A global collection of industry experts systematically discuss all innovation stages, complex processes with different unit operations, including solids processing and recycle flows, and the importance of integrated process validation. The book addresses the needs of engineers who want to increase their skill levels in various disciplines so that they are able to develop, commercialize and optimize processes. After reading this book, you will be able to acquire new skills and knowledge to collaborate across disciplines and develop creative solutions.
1. 2.1: Introduction - p. 13 2. 2.2: Microbiology and biochemistry basics - p. 13 3. 2.3: Fermentation media and environment - p. 21 4. 2.4: Growth kinetics and substrate utilization - p. 24 5. 2.5: From vial to production fermenter - p. 27 6. 2.6: Oxygen transfer and utilization - p. 29 7. 2.7: Mixing in aerobic fermentation vessels - p. 37 8. 2.8: Sterilization - p. 43 9. 2.9: Heat generation - p. 56 10. 2.10: Scale-up - p. 60 11. Chapter 3 Fermentation and downstream processing: Part 2 - p. 69 12. Chapter 4 Liquid filtration - p. 113 13. Chapter 5 Cake-building filter technologies - p. 125 14. Chapter 6 Centrifugation - p. 133 15. Chapter 7 Dryers - p. 145 16. Chapter 8 Pressure filter dryer - p. 177 17. Chapter 9 Process automation systems - p. 191 18. Chapter 10 Process automation life cycles - p. 219 19. Chapter 11 Process automation platforms - p. 239 20. Chapter 12 Mixing and blending - p. 249 21. Chapter 13 Process development and integration by mathematical modeling and simulation tools - p. 273 22. Chapter 14 Process safety - p. 293 23. Chapter 15 Process commissioning - p. 307 24. Chapter 16 Holistic process integration and optimization: Large-scale hybrid process applications - p. 317 25. Chapter 17 From idea to 1 million ton year commercial plant - p. 339 26. Chapter 18 Scale-up challenges: Examples from refining and catalysis - p. 345 27. Chapter 19 Scale-up challenges: Wastewater - p. 351 28. Chapter 20 Hemp/biomass process steps - p. 355 29. Chapter 21 Techno-economic analyses - p. 373 30. Chapter 22 Project management - p. 413 31. Chapter 23 Decommissioning - p. 433 32. Index - p. 437
