Ion Channels and Calcium Signaling in the Microcirculation, Volume 85, the latest release in the Current Topics in Membranes series, highlights the latest advances in the expression and function of ion channels and calcium signaling in vascular smooth muscle and endothelial cells in resistance arteries, arterioles and capillaries, critical components of microcirculation, the business end of the cardiovascular system. Leading experts have contributed chapters, including Smooth muscle ion channels and calcium signaling in the regulation of striated muscle arteriolar tone; Endothelial KIR channels as a key component of shear stress-induced mechanotransduction; Endothelial TRPV4 channels and vasodilator reactivity, and much more.
Additional sections cover cerebral capillary endothelial TRPA channels and the regulation of blood flow; Endothelial mineralocorticoid receptors and the regulation of TRPV4 function in cerebral parenchymal arterioles in hypertension; Subcellular calcium signaling and myogenic tone development in the retinal microcirculation; Microvascular KIR channels: Basis, properties and regulation by lipid and hemodynamic forces, Ion channels and calcium signaling in capillary endothelial cells; Ion channels and calcium signaling in bladder arterioles and resistance arteries, and Myoendothelial feedback and endothelial IKCa and sKCa channels.
1. Chapter One: Introduction to ion channels and calcium signaling in the microcirculation - p. page_xiv 2. Chapter Two: Ion channels and the regulation of myogenic tone in peripheral arterioles - p. page_18 3. Chapter Three: Endothelial inwardly-rectifying K+ channels as a key component of shear stress-induced mechanotransduction - p. page_58 4. Chapter Four: Endothelial TRPV4 channels and vasodilator reactivity - p. page_88 5. Chapter Five: Regulation of vascular tone by transient receptor potential ankyrin 1 channels - p. page_117 6. Chapter Six: Regulation of ion channels in the microcirculation by mineralocorticoid receptor activation - p. page_150 7. Chapter Seven: Ion channels and myogenic activity in retinal arterioles - p. page_185 8. Chapter Eight: KIR channels in the microvasculature: Regulatory properties and the lipid-hemodynamic environment - p. page_226 9. Chapter Nine: Ion channels in capillary endothelium - p. page_259 10. Chapter Ten: Excitability and contractility in arterioles and venules from the urinary bladder - p. page_300 11. Chapter Eleven: Intrinsic regulation of microvascular tone by myoendothelial feedback circuits - p. page_326
Ion Channels and Calcium Signaling in the Microcirculation, Volume 85, the latest release in the Current Topics in Membranes series, highlights the latest advances in the expression and function of ion channels and calcium signaling in vascular smooth muscle and endothelial cells in resistance arteries, arterioles and capillaries, critical components of microcirculation, the business end of the cardiovascular system. Leading experts have contributed chapters, including Smooth muscle ion channels and calcium signaling in the regulation of striated muscle arteriolar tone; Endothelial KIR channels as a key component of shear stress-induced mechanotransduction; Endothelial TRPV4 channels and vasodilator reactivity, and much more.
Additional sections cover cerebral capillary endothelial TRPA channels and the regulation of blood flow; Endothelial mineralocorticoid receptors and the regulation of TRPV4 function in cerebral parenchymal arterioles in hypertension; Subcellular calcium signaling and myogenic tone development in the retinal microcirculation; Microvascular KIR channels: Basis, properties and regulation by lipid and hemodynamic forces, Ion channels and calcium signaling in capillary endothelial cells; Ion channels and calcium signaling in bladder arterioles and resistance arteries, and Myoendothelial feedback and endothelial IKCa and sKCa channels.
1. Chapter One: Introduction to ion channels and calcium signaling in the microcirculation - p. page_xiv 2. Chapter Two: Ion channels and the regulation of myogenic tone in peripheral arterioles - p. page_18 3. Chapter Three: Endothelial inwardly-rectifying K+ channels as a key component of shear stress-induced mechanotransduction - p. page_58 4. Chapter Four: Endothelial TRPV4 channels and vasodilator reactivity - p. page_88 5. Chapter Five: Regulation of vascular tone by transient receptor potential ankyrin 1 channels - p. page_117 6. Chapter Six: Regulation of ion channels in the microcirculation by mineralocorticoid receptor activation - p. page_150 7. Chapter Seven: Ion channels and myogenic activity in retinal arterioles - p. page_185 8. Chapter Eight: KIR channels in the microvasculature: Regulatory properties and the lipid-hemodynamic environment - p. page_226 9. Chapter Nine: Ion channels in capillary endothelium - p. page_259 10. Chapter Ten: Excitability and contractility in arterioles and venules from the urinary bladder - p. page_300 11. Chapter Eleven: Intrinsic regulation of microvascular tone by myoendothelial feedback circuits - p. page_326
