Ion Channels in Health and Disease provides key insight to allow researchers to generate discoveries across disease states. A single resource that integrates disparate areas of biology and disease ion channel biology, this publication includes cross-referencing for disease, channels, and tissues. Offers a broad view of research of interest to early and experienced researchers across biological and biomedical research.
1. Introduction - p. 131 2. Ion Channels Identified in Cancers - p. 131 3. Regulation of Ion Channel Expression in Cancer - p. 136 4. Ion Channel Function in Cancer Cells - p. 137 5. Ion Channel Involvement in the Hallmarks of Cancer - p. 144 6. Ion Channels as Therapeutic Targets - p. 147 7. Concluding Remarks - p. 151 8. Chapter 7. TMEM16 Membrane Proteins in Health and Disease - p. 165 9. Chapter 8. KATP Channels in the Pancreas: Hyperinsulinism and Diabetes - p. 199 10. Chapter 9. The Role of Sperm Ion Channels in Reproduction - p. 223 11. Chapter 10. Mutations of Sodium Channel SCN8A (Nav1.6) in Neurological Disease - p. 239 12. Chapter 11. Alternative Splicing and RNA Editing of Voltage-Gated Ion Channels: Implications in Health and Disease - p. 265 13. Chapter 12. Computational Modeling of Cardiac K+ Channels and Channelopathies - p. 293 14. Chapter 13. Connexins and Heritable Human Diseases - p. 331 15. Chapter 14. Complexity of Molecular Genetics in the Inherited Cardiac Arrhythmias - p. 345 16. Other Volumes in the Perspectives on Translational Cell Biology Series - p. 369 17. Index - p. 373
Ion Channels in Health and Disease provides key insight to allow researchers to generate discoveries across disease states. A single resource that integrates disparate areas of biology and disease ion channel biology, this publication includes cross-referencing for disease, channels, and tissues. Offers a broad view of research of interest to early and experienced researchers across biological and biomedical research.
1. Introduction - p. 131 2. Ion Channels Identified in Cancers - p. 131 3. Regulation of Ion Channel Expression in Cancer - p. 136 4. Ion Channel Function in Cancer Cells - p. 137 5. Ion Channel Involvement in the Hallmarks of Cancer - p. 144 6. Ion Channels as Therapeutic Targets - p. 147 7. Concluding Remarks - p. 151 8. Chapter 7. TMEM16 Membrane Proteins in Health and Disease - p. 165 9. Chapter 8. KATP Channels in the Pancreas: Hyperinsulinism and Diabetes - p. 199 10. Chapter 9. The Role of Sperm Ion Channels in Reproduction - p. 223 11. Chapter 10. Mutations of Sodium Channel SCN8A (Nav1.6) in Neurological Disease - p. 239 12. Chapter 11. Alternative Splicing and RNA Editing of Voltage-Gated Ion Channels: Implications in Health and Disease - p. 265 13. Chapter 12. Computational Modeling of Cardiac K+ Channels and Channelopathies - p. 293 14. Chapter 13. Connexins and Heritable Human Diseases - p. 331 15. Chapter 14. Complexity of Molecular Genetics in the Inherited Cardiac Arrhythmias - p. 345 16. Other Volumes in the Perspectives on Translational Cell Biology Series - p. 369 17. Index - p. 373
