Ion-Exchange Chromatography and Related Techniques defines the current state-of-the-art in ion-exchange chromatography and related techniques and their implementation in laboratory and industrial practice. This book provides a compact source of information to facilitate the transfer of knowledge and experience acquired by separation science specialists to colleagues from diverse backgrounds who need to acquire fundamental and practical information to facilitate progress in research and management functions reliant on information acquired by separation. Individual chapters written by recognized experts lending credibility to the work will allow this book to serve as a high value reference source of current information for analytical and biopharmaceutical chemists.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contributors - p. xi 7. Chapter 1. Concepts and milestones in the development of ion-exchange chromatography - p. 1 8. Chapter 2. Equilibria and kinetics of ion-exchange of biopolymers - p. 25 9. Chapter 3. Stationary phases for ion separations - p. 49 10. Chapter 4. Stationary phases for the separation of biopolymers by ion-exchange chromatography - p. 69 11. Chapter 5. Ion-exchange separations of biomacromolecules on grafted and surface-modified polymers - p. 98 12. Chapter 6. Extraction chromatography of actinides - p. 131 13. Chapter 7. Ion-exchange membrane chromatography - p. 145 14. Chapter 8. Ion-exclusion chromatography - p. 163 15. Chapter 9. Chelation ion chromatography - p. 191 16. Chapter 10. Displacement chromatography with ion-exchangers - p. 211 17. Chapter 11. Instrumentation for ion chromatography - p. 227 18. Chapter 12. Instrument platforms for large-scale ion-exchange separations of biomolecules - p. 243 19. Chapter 13. Method development for large molecules IEX separations - p. 268 20. Chapter 14. Sample preparation for ion-exchange separations - p. 287 21. Chapter 15. Separation of ions by ion chromatography - p. 315 22. Chapter 16. Applications of ion chromatography in environmental analysis - p. 343 23. Chapter 17. Applications of ion chromatography in food analysis - p. 354 24. Chapter 18. Separation of saccharides by ion-exchange chromatography - p. 371 25. Chapter 19. Separation of oligonucleotides by ion-exchange chromatography - p. 387 26. Chapter 20. Separation of oligonucleotides by ion-exchange and ion-pair chromatography - p. 413 27. Chapter 21. Separation of proteins by ion-exchange chromatography - p. 435 28. Chapter 22. Separation of proteins by mixed-mode chromatography - p. 461 29. Chapter 23. Process modeling of protein separations by ion-exchange chromatography - p. 473 30. Chapter 24. Applications of ion-exchange chromatography for the purification of antibodies - p. 505 31. Chapter 25. Conformational changes of biomolecules in ion-exchange chromatography - p. 521 32. Chapter 26. Continuous ion-exchange chromatography for protein polishing and enrichment - p. 535 33. Chapter 27. Separation of bio-particles by ion-exchange chromatography - p. 564 34. Chapter 28. Virus removal in bioprocessing using charged media - p. 579 35. Chapter 29. Role of temperature in ion-exchange processes of separation and purification - p. 591 36. Index - p. 615
Ion-Exchange Chromatography and Related Techniques defines the current state-of-the-art in ion-exchange chromatography and related techniques and their implementation in laboratory and industrial practice. This book provides a compact source of information to facilitate the transfer of knowledge and experience acquired by separation science specialists to colleagues from diverse backgrounds who need to acquire fundamental and practical information to facilitate progress in research and management functions reliant on information acquired by separation. Individual chapters written by recognized experts lending credibility to the work will allow this book to serve as a high value reference source of current information for analytical and biopharmaceutical chemists.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contributors - p. xi 7. Chapter 1. Concepts and milestones in the development of ion-exchange chromatography - p. 1 8. Chapter 2. Equilibria and kinetics of ion-exchange of biopolymers - p. 25 9. Chapter 3. Stationary phases for ion separations - p. 49 10. Chapter 4. Stationary phases for the separation of biopolymers by ion-exchange chromatography - p. 69 11. Chapter 5. Ion-exchange separations of biomacromolecules on grafted and surface-modified polymers - p. 98 12. Chapter 6. Extraction chromatography of actinides - p. 131 13. Chapter 7. Ion-exchange membrane chromatography - p. 145 14. Chapter 8. Ion-exclusion chromatography - p. 163 15. Chapter 9. Chelation ion chromatography - p. 191 16. Chapter 10. Displacement chromatography with ion-exchangers - p. 211 17. Chapter 11. Instrumentation for ion chromatography - p. 227 18. Chapter 12. Instrument platforms for large-scale ion-exchange separations of biomolecules - p. 243 19. Chapter 13. Method development for large molecules IEX separations - p. 268 20. Chapter 14. Sample preparation for ion-exchange separations - p. 287 21. Chapter 15. Separation of ions by ion chromatography - p. 315 22. Chapter 16. Applications of ion chromatography in environmental analysis - p. 343 23. Chapter 17. Applications of ion chromatography in food analysis - p. 354 24. Chapter 18. Separation of saccharides by ion-exchange chromatography - p. 371 25. Chapter 19. Separation of oligonucleotides by ion-exchange chromatography - p. 387 26. Chapter 20. Separation of oligonucleotides by ion-exchange and ion-pair chromatography - p. 413 27. Chapter 21. Separation of proteins by ion-exchange chromatography - p. 435 28. Chapter 22. Separation of proteins by mixed-mode chromatography - p. 461 29. Chapter 23. Process modeling of protein separations by ion-exchange chromatography - p. 473 30. Chapter 24. Applications of ion-exchange chromatography for the purification of antibodies - p. 505 31. Chapter 25. Conformational changes of biomolecules in ion-exchange chromatography - p. 521 32. Chapter 26. Continuous ion-exchange chromatography for protein polishing and enrichment - p. 535 33. Chapter 27. Separation of bio-particles by ion-exchange chromatography - p. 564 34. Chapter 28. Virus removal in bioprocessing using charged media - p. 579 35. Chapter 29. Role of temperature in ion-exchange processes of separation and purification - p. 591 36. Index - p. 615
