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The ninth edition of this best-selling textbook of clinical medicine builds even further on its formidable, prize-winning formula of excellence, comprehensiveness and accessibility.

‘This book is stunning in its breadth and ease-of-use. It still remains the "gold standard", thorough guide to clinical medicine its forefathers were.’ BMA Medical Book Awards judges.

New to this edition:

  • 2 new chapters: Global Health and Women’s Health.
  • 25 new authors.
  • New online editor, Adam Feather, with a team of young doctors to augment the e-book which accompanies the print book with clinical tips, key learning points, drug tips, learning challenges, case studies and MCQs.
  • Full text redesign to incorporate:

New system overview diagrams for clinical chapters.

New coloured headings to help identify content relating to disease, management, investigations etc.

New icons to aid text navigation.

11 new members and a new co-editor, Senaka Rajapakse, of the International Advisory Board.

Edited by Kumar and Clark, clinicians and educators of world-renowned expertise.

Authors comprise consultants at the top of their fields, paired with younger doctors closer to the exam experience, to ensure authority and relevance.

Enhanced e-book accompanies the print book, for ease of transportation and use on the move.

International Advisory Board, led by Professor Janaka de Silva and Professor Senaka Rajapakse, providing guidance for global coverage from across the world.

Contributions to the e-book by members of the International Advisory Board to amplify areas of clinical importance in their parts of the world

1. Introduction - p. 183 2. Water and Electrolyte Balance - p. 184 3. Dietary Requirements - p. 184 4. Protein–Energy Malnutrition - p. 189 5. Vitamins - p. 194 6. Minerals - p. 202 7. Nutrition and Ageing - p. 204 8. Obesity - p. 206 9. Nutritional Support - p. 212 10. Food Allergy and Food Intolerance - p. 216 11. Alcohol - p. 217 12. Bibliography - p. 218 13. Significant websites - p. 218 14. Section 3 Clinical practice - p. 218 15. 11 Infectious diseases and tropical medicine - p. 219 16. Infection and Infectious Disease - p. 222 17. Viral Infections - p. 246 18. Transmissible Spongiform Encephalopathies (Prion Diseases) - p. 267 19. Bacterial Infections - p. 268 20. Fungal Infections - p. 294 21. Protozoal Infections - p. 297 22. Helminthic Infections - p. 307 23. Arthropod Ectoparasites - p. 316 24. 12 Sexually transmitted infections and human immunodeficiency virus - p. 317 25. Sexually Transmitted Infections - p. 317 26. Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome - p. 331 27. Bibliography - p. 355 28. 13 Gastrointestinal disease - p. 357 29. Introduction - p. 359 30. Clinical Approach to the Patient with Gastrointestinal Disease - p. 358 31. The Mouth - p. 363 32. The Salivary Glands - p. 365 33. The Pharynx and Oesophagus - p. 365 34. The Stomach and Duodenum - p. 376 35. Acute and Chronic Gastrointestinal Bleeding - p. 384 36. The Small Intestine - p. 388 37. Inflammatory Bowel Disease - p. 404 38. The Colon and Rectum - p. 415 39. Diarrhoea - p. 425 40. Functional Gastrointestinal Disorders - p. 428 41. The Acute Abdomen - p. 432 42. The Peritoneum - p. 435 43. Bibliography - p. 436 44. Significant websites - p. 436 45. 14 Liver disease - p. 437 46. Introduction - p. 437 47. Anatomy of the Liver and Biliary System - p. 440 48. Functions of the Liver - p. 441 49. Clinical Approach to the Patient with Liver Disease - p. 443 50. Jaundice - p. 448 51. Hepatitis - p. 451 52. Acute Hepatic Failure - p. 462 53. Autoimmune Hepatitis - p. 463 54. Drug-Induced Chronic Hepatitis - p. 464 55. Chronic Hepatitis of Unknown Cause - p. 464 56. Non-Alcoholic Fatty Liver Disease - p. 465 57. Cirrhosis - p. 465 58. Alcoholic Liver Disease - p. 480 59. Budd–Chiari Syndrome - p. 482 60. Hepatic Sinusoidal Obstruction Syndrome - p. 482 61. Fibropolycystic Diseases - p. 483 62. Liver Abscess - p. 483 63. Other Infections of the Liver - p. 484 64. Liver Disease in Pregnancy - p. 485 65. Liver Tumours - p. 485 66. Miscellaneous Conditions of the Liver - p. 486 67. Drugs and the Liver - p. 487 68. Bibliography - p. 488 69. 15 Biliary tract and pancreatic disease - p. 489 70. 16 Haematological disease - p. 515 71. The Red Cell - p. 519 72. The Spleen - p. 552 73. Blood Transfusion - p. 553 74. The White Cell - p. 562 75. Haemostasis and Thrombosis - p. 564 76. Bibliography - p. 581 77. Significant websites - p. 581 78. 17 Malignant disease - p. 583 79. Cancer Treatment - p. 594 80. Acute Oncology - p. 604 81. Haematological Malignancies - p. 606 82. Common Solid Tumour Treatment - p. 629 83. 18 Rheumatic disease - p. 645 84. Introduction - p. 645 85. Anatomy and Physiology of the Normal Joint - p. 647 86. Clinical Approach to the Patient with Rheumatic Disease - p. 648 87. Common Regional Musculoskeletal Problems - p. 652 88. Chronic Pain Syndromes - p. 663 89. Analgesic and Anti-Inflammatory Drugs for Musculoskeletal Problems - p. 665 90. Disorders of collagen - p. 666 91. Osteoarthritis - p. 667 92. Inflammatory Arthritis - p. 671 93. Rheumatoid arthritis - p. 672 94. Infections of Joints - p. 690 95. Autoimmune Rheumatic Diseases - p. 692 96. Systemic Inflammatory Vasculitis - p. 699 97. Arthritis in Children - p. 702 98. Rheumatological Problems Seen in Other Diseases - p. 704 99. Miscellaneous Arthropathies - p. 705 100. 19 Bone disease - p. 707 101. 20 Kidney and urinary tract disease - p. 721 102. Anatomy and Physiology of the Kidney and Urinary Tract - p. 723 103. Clinical Approach to the Patient with Kidney and Urinary Tract Disease - p. 729 104. The Glomerulus and Glomerular Disease - p. 733 105. Kidney Involvement in Other Diseases - p. 749 106. Hypertension and the Kidney - p. 751 107. Other Vascular Disorders of the Kidney - p. 753 108. Renal Calculi and Nephrocalcinosis - p. 754 109. Urinary Tract Obstruction - p. 758 110. Drugs and the Kidney - p. 761 111. Urinary Tract Infection - p. 762 112. Tubulointerstitial Nephritis - p. 767 113. Acute Kidney Injury - p. 769 114. Chronic Kidney Disease - p. 774 115. Cystic Renal Disease - p. 789 116. Tumours of the Kidney and Genitourinary Tract - p. 791 117. Diseases of the Prostate Gland - p. 792 118. The Urinary Tract in the Elderly - p. 793 119. Bibliography - p. 793 120. Significant websites - p. 793 121. 21 Neurological disease - p. 795 122. Introduction - p. 797 123. Clinical Approach to the Patient with Neurological Disease - p. 797 124. Functional Neuroanatomy - p. 798 125. Cranial Nerves - p. 802 126. Motor Control Systems - p. 811 127. Lower Motor Neurone Lesions - p. 815 128. Sensory Pathways and Pain - p. 815 129. Bladder Control and Sexual Dysfunction - p. 820 130. Investigation of Neurological Disease - p. 821 131. Unconsciousness and Coma - p. 825 132. Stroke - p. 829 133. Intracranial haemorrhage - p. 838 134. Headache, Migraine and Facial Pain - p. 841 135. Epilepsy and Loss of Consciousness - p. 846 136. Movement Disorders - p. 852 137. Neuroinflammatory Disorders - p. 857 138. Nervous System Infection - p. 862 139. Brain Tumours - p. 868 140. Hydrocephalus - p. 870 141. Traumatic Brain Injury - p. 871 142. Spinal Cord Disease - p. 872 143. Neurodegenerative Diseases - p. 874 144. Congenital Disorders - p. 880 145. Neurogenetic Disorders - p. 880 146. Paraneoplastic Syndromes - p. 881 147. Peripheral Nerve Disease - p. 881 148. Muscle Diseases - p. 888 149. Bibliography - p. 892 150. Significant websites - p. 892 151. 22 Psychological medicine - p. 893 152. Introduction - p. 893 153. Clinical Approach to the Patient with a Psychiatric Disorder - p. 893 154. Classification of Psychiatric Disorders - p. 897 155. Aetiology of Psychiatric Disorders - p. 898 156. Psychiatric Aspects of Physical Diseases - p. 898 157. The Sick Role and Illness Behaviour - p. 899 158. Functional Somatic Syndromes - p. 899 159. Somatoform Disorders - p. 902 160. Dissociative/Conversion Disorders - p. 903 161. Sleep Difficulties - p. 904 162. Mood (Affective) Disorders - p. 906 163. Suicide and Self-Harm - p. 915 164. Anxiety Disorders - p. 915 165. Alcohol Misuse and Dependence - p. 920 166. Drug Misuse and Dependence - p. 922 167. Schizophrenia - p. 924 168. Organic Mental Disorders - p. 926 169. Eating Disorders - p. 927 170. Sexual Disorders - p. 928 171. Personality Disorders - p. 929 172. Involuntary Detention or Commitment - p. 929 173. Mental Capacity Act - p. 930 174. Further reading - p. 930 175. Significant websites - p. 930 176. 23 Cardiovascular disease - p. 931 177. Cardiac Arrhythmias - p. 962 178. Heart Failure - p. 980 179. Coronary Artery Disease - p. 991 180. Valvular Heart Disease - p. 1006 181. Infective Endocarditis - p. 1017 182. Congenital Heart Disease - p. 1021 183. Marfan Syndrome - p. 1028 184. Pulmonary Heart Disease - p. 1029 185. Myocardial and Endocardial Disease - p. 1035 186. Pericardial Disease - p. 1042 187. Systemic Hypertension - p. 1046 188. Peripheral Vascular Disease - p. 1049 189. Significant websites - p. 1056 190. 24 Respiratory disease - p. 1057 191. Introduction - p. 1057 192. Anatomy of the Respiratory System - p. 1059 193. Physiology of the Respiratory System - p. 1061 194. Clinical Approach to the Patient with Respiratory Disease - p. 1066 195. Smoking - p. 1074 196. Diseases of the Upper Respiratory Tract - p. 1075 197. Diseases of the Lower Respiratory Tract - p. 1079 198. Asthma - p. 1090 199. Pneumonia - p. 1100 200. Tuberculosis - p. 1106 201. Diffuse Parenchymal Lung Diseases - p. 1113 202. Occupational Lung Disease - p. 1124 203. Lung Cysts - p. 1126 204. Tumours of the Respiratory Tract - p. 1126 205. Disorders of the Chest Wall and Pleura - p. 1133 206. Disorders of the Diaphragm - p. 1135 207. Mediastinal Lesions - p. 1136 208. Significant websites - p. 1137 209. 25 Critical care medicine - p. 1139 210. 26 Endocrine disease - p. 1175 211. Introduction - p. 1175 212. Clinical Approach to the Patient with Endocrine Disease - p. 1175 213. The Pituitary Gland and Hypothalamus - p. 1182 214. The Thyroid Axis - p. 1199 215. Reproduction and Sex - p. 1212 216. The Adrenal Axis - p. 1224 217. The Thirst Axis - p. 1232 218. Disorders of Calcium Metabolism - p. 1235 219. Other Endocrine Disorders - p. 1239 220. Bibliography - p. 1240 221. Significant websites - p. 1240 222. 27 Diabetes mellitus - p. 1241 223. 28 Lipid and metabolic disorders - p. 1277 224. 29 Women's health - p. 1293 225. 30 Ear, nose and throat and eye disease - p. 1311 226. 31 Skin disease - p. 1337 227. Introduction - p. 1337 228. Structure and Function of the Skin - p. 1337 229. Clinical Approach to the Patient with Skin Disease - p. 1339 230. Infections - p. 1341 231. Papulo-Squamous/Inflammatory Rashes - p. 1348 232. Facial Rashes - p. 1359 233. Photodermatology - p. 1361 234. Erythroderma - p. 1362 235. Cutaneous Signs of Systemic Disease - p. 1363 236. Bullous Disease - p. 1368 237. Skin Tumours - p. 1371 238. Disorders of Blood Vessels and Lymphatics - p. 1375 239. Disorders of Collagen and Elastic Tissue - p. 1378 240. Disorders of Pigmentation - p. 1378 241. Disorders of the Nails - p. 1379 242. Disorders of Hair - p. 1380 243. Birth Marks/Neonatal Rashes - p. 1381 244. Drug Eruptions - p. 1382 245. Human Immunodeficiency Virus and the Skin - p. 1384 246. Principles of Topical Therapy - p. 1385 247. Bibliography - p. 1386 248. Significant Websites - p. 1386 249. Index - p. 1387

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Descripcion
Descripción

The ninth edition of this best-selling textbook of clinical medicine builds even further on its formidable, prize-winning formula of excellence, comprehensiveness and accessibility.

‘This book is stunning in its breadth and ease-of-use. It still remains the "gold standard", thorough guide to clinical medicine its forefathers were.’ BMA Medical Book Awards judges.

New to this edition:

  • 2 new chapters: Global Health and Women’s Health.
  • 25 new authors.
  • New online editor, Adam Feather, with a team of young doctors to augment the e-book which accompanies the print book with clinical tips, key learning points, drug tips, learning challenges, case studies and MCQs.
  • Full text redesign to incorporate:

New system overview diagrams for clinical chapters.

New coloured headings to help identify content relating to disease, management, investigations etc.

New icons to aid text navigation.

11 new members and a new co-editor, Senaka Rajapakse, of the International Advisory Board.

Edited by Kumar and Clark, clinicians and educators of world-renowned expertise.

Authors comprise consultants at the top of their fields, paired with younger doctors closer to the exam experience, to ensure authority and relevance.

Enhanced e-book accompanies the print book, for ease of transportation and use on the move.

International Advisory Board, led by Professor Janaka de Silva and Professor Senaka Rajapakse, providing guidance for global coverage from across the world.

Contributions to the e-book by members of the International Advisory Board to amplify areas of clinical importance in their parts of the world

1. Introduction - p. 183 2. Water and Electrolyte Balance - p. 184 3. Dietary Requirements - p. 184 4. Protein–Energy Malnutrition - p. 189 5. Vitamins - p. 194 6. Minerals - p. 202 7. Nutrition and Ageing - p. 204 8. Obesity - p. 206 9. Nutritional Support - p. 212 10. Food Allergy and Food Intolerance - p. 216 11. Alcohol - p. 217 12. Bibliography - p. 218 13. Significant websites - p. 218 14. Section 3 Clinical practice - p. 218 15. 11 Infectious diseases and tropical medicine - p. 219 16. Infection and Infectious Disease - p. 222 17. Viral Infections - p. 246 18. Transmissible Spongiform Encephalopathies (Prion Diseases) - p. 267 19. Bacterial Infections - p. 268 20. Fungal Infections - p. 294 21. Protozoal Infections - p. 297 22. Helminthic Infections - p. 307 23. Arthropod Ectoparasites - p. 316 24. 12 Sexually transmitted infections and human immunodeficiency virus - p. 317 25. Sexually Transmitted Infections - p. 317 26. Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome - p. 331 27. Bibliography - p. 355 28. 13 Gastrointestinal disease - p. 357 29. Introduction - p. 359 30. Clinical Approach to the Patient with Gastrointestinal Disease - p. 358 31. The Mouth - p. 363 32. The Salivary Glands - p. 365 33. The Pharynx and Oesophagus - p. 365 34. The Stomach and Duodenum - p. 376 35. Acute and Chronic Gastrointestinal Bleeding - p. 384 36. The Small Intestine - p. 388 37. Inflammatory Bowel Disease - p. 404 38. The Colon and Rectum - p. 415 39. Diarrhoea - p. 425 40. Functional Gastrointestinal Disorders - p. 428 41. The Acute Abdomen - p. 432 42. The Peritoneum - p. 435 43. Bibliography - p. 436 44. Significant websites - p. 436 45. 14 Liver disease - p. 437 46. Introduction - p. 437 47. Anatomy of the Liver and Biliary System - p. 440 48. Functions of the Liver - p. 441 49. Clinical Approach to the Patient with Liver Disease - p. 443 50. Jaundice - p. 448 51. Hepatitis - p. 451 52. Acute Hepatic Failure - p. 462 53. Autoimmune Hepatitis - p. 463 54. Drug-Induced Chronic Hepatitis - p. 464 55. Chronic Hepatitis of Unknown Cause - p. 464 56. Non-Alcoholic Fatty Liver Disease - p. 465 57. Cirrhosis - p. 465 58. Alcoholic Liver Disease - p. 480 59. Budd–Chiari Syndrome - p. 482 60. Hepatic Sinusoidal Obstruction Syndrome - p. 482 61. Fibropolycystic Diseases - p. 483 62. Liver Abscess - p. 483 63. Other Infections of the Liver - p. 484 64. Liver Disease in Pregnancy - p. 485 65. Liver Tumours - p. 485 66. Miscellaneous Conditions of the Liver - p. 486 67. Drugs and the Liver - p. 487 68. Bibliography - p. 488 69. 15 Biliary tract and pancreatic disease - p. 489 70. 16 Haematological disease - p. 515 71. The Red Cell - p. 519 72. The Spleen - p. 552 73. Blood Transfusion - p. 553 74. The White Cell - p. 562 75. Haemostasis and Thrombosis - p. 564 76. Bibliography - p. 581 77. Significant websites - p. 581 78. 17 Malignant disease - p. 583 79. Cancer Treatment - p. 594 80. Acute Oncology - p. 604 81. Haematological Malignancies - p. 606 82. Common Solid Tumour Treatment - p. 629 83. 18 Rheumatic disease - p. 645 84. Introduction - p. 645 85. Anatomy and Physiology of the Normal Joint - p. 647 86. Clinical Approach to the Patient with Rheumatic Disease - p. 648 87. Common Regional Musculoskeletal Problems - p. 652 88. Chronic Pain Syndromes - p. 663 89. Analgesic and Anti-Inflammatory Drugs for Musculoskeletal Problems - p. 665 90. Disorders of collagen - p. 666 91. Osteoarthritis - p. 667 92. Inflammatory Arthritis - p. 671 93. Rheumatoid arthritis - p. 672 94. Infections of Joints - p. 690 95. Autoimmune Rheumatic Diseases - p. 692 96. Systemic Inflammatory Vasculitis - p. 699 97. Arthritis in Children - p. 702 98. Rheumatological Problems Seen in Other Diseases - p. 704 99. Miscellaneous Arthropathies - p. 705 100. 19 Bone disease - p. 707 101. 20 Kidney and urinary tract disease - p. 721 102. Anatomy and Physiology of the Kidney and Urinary Tract - p. 723 103. Clinical Approach to the Patient with Kidney and Urinary Tract Disease - p. 729 104. The Glomerulus and Glomerular Disease - p. 733 105. Kidney Involvement in Other Diseases - p. 749 106. Hypertension and the Kidney - p. 751 107. Other Vascular Disorders of the Kidney - p. 753 108. Renal Calculi and Nephrocalcinosis - p. 754 109. Urinary Tract Obstruction - p. 758 110. Drugs and the Kidney - p. 761 111. Urinary Tract Infection - p. 762 112. Tubulointerstitial Nephritis - p. 767 113. Acute Kidney Injury - p. 769 114. Chronic Kidney Disease - p. 774 115. Cystic Renal Disease - p. 789 116. Tumours of the Kidney and Genitourinary Tract - p. 791 117. Diseases of the Prostate Gland - p. 792 118. The Urinary Tract in the Elderly - p. 793 119. Bibliography - p. 793 120. Significant websites - p. 793 121. 21 Neurological disease - p. 795 122. Introduction - p. 797 123. Clinical Approach to the Patient with Neurological Disease - p. 797 124. Functional Neuroanatomy - p. 798 125. Cranial Nerves - p. 802 126. Motor Control Systems - p. 811 127. Lower Motor Neurone Lesions - p. 815 128. Sensory Pathways and Pain - p. 815 129. Bladder Control and Sexual Dysfunction - p. 820 130. Investigation of Neurological Disease - p. 821 131. Unconsciousness and Coma - p. 825 132. Stroke - p. 829 133. Intracranial haemorrhage - p. 838 134. Headache, Migraine and Facial Pain - p. 841 135. Epilepsy and Loss of Consciousness - p. 846 136. Movement Disorders - p. 852 137. Neuroinflammatory Disorders - p. 857 138. Nervous System Infection - p. 862 139. Brain Tumours - p. 868 140. Hydrocephalus - p. 870 141. Traumatic Brain Injury - p. 871 142. Spinal Cord Disease - p. 872 143. Neurodegenerative Diseases - p. 874 144. Congenital Disorders - p. 880 145. Neurogenetic Disorders - p. 880 146. Paraneoplastic Syndromes - p. 881 147. Peripheral Nerve Disease - p. 881 148. Muscle Diseases - p. 888 149. Bibliography - p. 892 150. Significant websites - p. 892 151. 22 Psychological medicine - p. 893 152. Introduction - p. 893 153. Clinical Approach to the Patient with a Psychiatric Disorder - p. 893 154. Classification of Psychiatric Disorders - p. 897 155. Aetiology of Psychiatric Disorders - p. 898 156. Psychiatric Aspects of Physical Diseases - p. 898 157. The Sick Role and Illness Behaviour - p. 899 158. Functional Somatic Syndromes - p. 899 159. Somatoform Disorders - p. 902 160. Dissociative/Conversion Disorders - p. 903 161. Sleep Difficulties - p. 904 162. Mood (Affective) Disorders - p. 906 163. Suicide and Self-Harm - p. 915 164. Anxiety Disorders - p. 915 165. Alcohol Misuse and Dependence - p. 920 166. Drug Misuse and Dependence - p. 922 167. Schizophrenia - p. 924 168. Organic Mental Disorders - p. 926 169. Eating Disorders - p. 927 170. Sexual Disorders - p. 928 171. Personality Disorders - p. 929 172. Involuntary Detention or Commitment - p. 929 173. Mental Capacity Act - p. 930 174. Further reading - p. 930 175. Significant websites - p. 930 176. 23 Cardiovascular disease - p. 931 177. Cardiac Arrhythmias - p. 962 178. Heart Failure - p. 980 179. Coronary Artery Disease - p. 991 180. Valvular Heart Disease - p. 1006 181. Infective Endocarditis - p. 1017 182. Congenital Heart Disease - p. 1021 183. Marfan Syndrome - p. 1028 184. Pulmonary Heart Disease - p. 1029 185. Myocardial and Endocardial Disease - p. 1035 186. Pericardial Disease - p. 1042 187. Systemic Hypertension - p. 1046 188. Peripheral Vascular Disease - p. 1049 189. Significant websites - p. 1056 190. 24 Respiratory disease - p. 1057 191. Introduction - p. 1057 192. Anatomy of the Respiratory System - p. 1059 193. Physiology of the Respiratory System - p. 1061 194. Clinical Approach to the Patient with Respiratory Disease - p. 1066 195. Smoking - p. 1074 196. Diseases of the Upper Respiratory Tract - p. 1075 197. Diseases of the Lower Respiratory Tract - p. 1079 198. Asthma - p. 1090 199. Pneumonia - p. 1100 200. Tuberculosis - p. 1106 201. Diffuse Parenchymal Lung Diseases - p. 1113 202. Occupational Lung Disease - p. 1124 203. Lung Cysts - p. 1126 204. Tumours of the Respiratory Tract - p. 1126 205. Disorders of the Chest Wall and Pleura - p. 1133 206. Disorders of the Diaphragm - p. 1135 207. Mediastinal Lesions - p. 1136 208. Significant websites - p. 1137 209. 25 Critical care medicine - p. 1139 210. 26 Endocrine disease - p. 1175 211. Introduction - p. 1175 212. Clinical Approach to the Patient with Endocrine Disease - p. 1175 213. The Pituitary Gland and Hypothalamus - p. 1182 214. The Thyroid Axis - p. 1199 215. Reproduction and Sex - p. 1212 216. The Adrenal Axis - p. 1224 217. The Thirst Axis - p. 1232 218. Disorders of Calcium Metabolism - p. 1235 219. Other Endocrine Disorders - p. 1239 220. Bibliography - p. 1240 221. Significant websites - p. 1240 222. 27 Diabetes mellitus - p. 1241 223. 28 Lipid and metabolic disorders - p. 1277 224. 29 Women's health - p. 1293 225. 30 Ear, nose and throat and eye disease - p. 1311 226. 31 Skin disease - p. 1337 227. Introduction - p. 1337 228. Structure and Function of the Skin - p. 1337 229. Clinical Approach to the Patient with Skin Disease - p. 1339 230. Infections - p. 1341 231. Papulo-Squamous/Inflammatory Rashes - p. 1348 232. Facial Rashes - p. 1359 233. Photodermatology - p. 1361 234. Erythroderma - p. 1362 235. Cutaneous Signs of Systemic Disease - p. 1363 236. Bullous Disease - p. 1368 237. Skin Tumours - p. 1371 238. Disorders of Blood Vessels and Lymphatics - p. 1375 239. Disorders of Collagen and Elastic Tissue - p. 1378 240. Disorders of Pigmentation - p. 1378 241. Disorders of the Nails - p. 1379 242. Disorders of Hair - p. 1380 243. Birth Marks/Neonatal Rashes - p. 1381 244. Drug Eruptions - p. 1382 245. Human Immunodeficiency Virus and the Skin - p. 1384 246. Principles of Topical Therapy - p. 1385 247. Bibliography - p. 1386 248. Significant Websites - p. 1386 249. Index - p. 1387

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