Lactic Acid Bacteria as Cell Factories: Synthetic Biology and Metabolic Engineering describes the most recent developments on the metabolic engineering and synthetic biology of Lactic Acid Bacteria (LAB) for production of biologically active biomolecules (enzymes, organic acids, bacteriocins, bioactive peptides, etc.), recombinant proteins, and their role in bioremediation. The book focuses on synthetic biology and metabolic engineering for the production of biologically active molecules such as bioactive peptides, polysaccharides, vitamins (Riboflavin), enzymes, organic acids (lactic and gamma-aminobutyric acid), flavor and aroma compounds, bacteriocins, recombinant proteins, etc.
Individual chapters are devoted to the production of biosurfactants and their applications and the bioremediation of heavy metals by LAB from aquatic environments. Two critical chapters address Genome editing of LAB: opportunities for food, feed and pharmaceuticals and A synthetic biology approach for plasmid DNA and Recombinant protein production. This book will be a valuable resource for those working in biology, biotechnology, biological engineering, chemical engineering, microbiology, food science and technology, genetics and synthetic biology.
1. Lactic Acid Bacteria as Cell Factories - p. i 2. Cover - p. i 3. Title Page - p. iii 4. Copyright Page - p. iv 5. Table of Contents - p. iv 6. Contributors - p. xi 7. Preface - p. xvii 8. 1 LAB as cell factories: A synthetic biology approach for plasmid DNA and recombinant protein production - p. 1 9. 2 Synthetic biology and metabolic engineering for improvement of lactic acid bacteria as cell factories - p. 17 10. 3 Overview of traditional, emerging, and future applications of LAB and most important contributions of genome editing tools for food, feed, and pharmaceuticals - p. 29 11. 4 Lactic acid bacteria in biorefineries - p. 49 12. 5 Lactic acid microbial production and recovery: Review and recent advances in bioprocess integration - p. 77 13. 6 Lactic acid bacteria for riboflavin production - p. 109 14. 7 Lactic acid bacterial cell factories for the production of gamma-aminobutyric acid - p. 121 15. 8 Use of exopolysaccharides from lactic acid bacteria to develop cereal-based food: Perspectives and challenges for Burkina Faso - p. 153 16. 9 Lactic acid bacteria for the generation of bioactive peptides - p. 165 17. 10 Lactic acid bacteria as potential sources of enzymes: From genes to industrial applications - p. 183 18. 11 Amylolytic lactic acid bacteria: Cell factories for direct lactic acid production from biomass by simultaneous saccharification and fermentation - p. 199 19. 12 Role of phytases from lactic acid bacterial species in level upgradation of bioavailable micronutrients in food applications - p. 219 20. 13 Production of flavor compounds by lactic acid bacteria in fermented foods - p. 239 21. 14 Lactic acid bacteria as biocontrol agents of food pathogens - p. 271 22. 15 Biotechnology of bacteriocins production by LAB - p. 289 23. 16 Synthetic biology approaches for biosurfactants production by lactic acid bacteria - p. 311 24. 17 Biosurfactants production by LAB and emerging applications - p. 335 25. 18 The reducing power of LAB in fermentation and biomass production - p. 367 26. 19 Bioremediation of heavy metals from aquatic environments by lactic acid bacteria - p. 389 27. 20 Lactic acid bacteria and Bifidobacterium as potential psychotherapeutics - p. 401 28. Index - p. 413
Lactic Acid Bacteria as Cell Factories: Synthetic Biology and Metabolic Engineering describes the most recent developments on the metabolic engineering and synthetic biology of Lactic Acid Bacteria (LAB) for production of biologically active biomolecules (enzymes, organic acids, bacteriocins, bioactive peptides, etc.), recombinant proteins, and their role in bioremediation. The book focuses on synthetic biology and metabolic engineering for the production of biologically active molecules such as bioactive peptides, polysaccharides, vitamins (Riboflavin), enzymes, organic acids (lactic and gamma-aminobutyric acid), flavor and aroma compounds, bacteriocins, recombinant proteins, etc.
Individual chapters are devoted to the production of biosurfactants and their applications and the bioremediation of heavy metals by LAB from aquatic environments. Two critical chapters address Genome editing of LAB: opportunities for food, feed and pharmaceuticals and A synthetic biology approach for plasmid DNA and Recombinant protein production. This book will be a valuable resource for those working in biology, biotechnology, biological engineering, chemical engineering, microbiology, food science and technology, genetics and synthetic biology.
1. Lactic Acid Bacteria as Cell Factories - p. i 2. Cover - p. i 3. Title Page - p. iii 4. Copyright Page - p. iv 5. Table of Contents - p. iv 6. Contributors - p. xi 7. Preface - p. xvii 8. 1 LAB as cell factories: A synthetic biology approach for plasmid DNA and recombinant protein production - p. 1 9. 2 Synthetic biology and metabolic engineering for improvement of lactic acid bacteria as cell factories - p. 17 10. 3 Overview of traditional, emerging, and future applications of LAB and most important contributions of genome editing tools for food, feed, and pharmaceuticals - p. 29 11. 4 Lactic acid bacteria in biorefineries - p. 49 12. 5 Lactic acid microbial production and recovery: Review and recent advances in bioprocess integration - p. 77 13. 6 Lactic acid bacteria for riboflavin production - p. 109 14. 7 Lactic acid bacterial cell factories for the production of gamma-aminobutyric acid - p. 121 15. 8 Use of exopolysaccharides from lactic acid bacteria to develop cereal-based food: Perspectives and challenges for Burkina Faso - p. 153 16. 9 Lactic acid bacteria for the generation of bioactive peptides - p. 165 17. 10 Lactic acid bacteria as potential sources of enzymes: From genes to industrial applications - p. 183 18. 11 Amylolytic lactic acid bacteria: Cell factories for direct lactic acid production from biomass by simultaneous saccharification and fermentation - p. 199 19. 12 Role of phytases from lactic acid bacterial species in level upgradation of bioavailable micronutrients in food applications - p. 219 20. 13 Production of flavor compounds by lactic acid bacteria in fermented foods - p. 239 21. 14 Lactic acid bacteria as biocontrol agents of food pathogens - p. 271 22. 15 Biotechnology of bacteriocins production by LAB - p. 289 23. 16 Synthetic biology approaches for biosurfactants production by lactic acid bacteria - p. 311 24. 17 Biosurfactants production by LAB and emerging applications - p. 335 25. 18 The reducing power of LAB in fermentation and biomass production - p. 367 26. 19 Bioremediation of heavy metals from aquatic environments by lactic acid bacteria - p. 389 27. 20 Lactic acid bacteria and Bifidobacterium as potential psychotherapeutics - p. 401 28. Index - p. 413
