Large Animals as Models for Human Diseases, Volume 189 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of important topics, including Sheep as a model for neuroendocrinology research, Relevance of dog as a model for urologic diseases, Relevance of lactocrine hypothesis to human maternal programming of development, Comparative aspects of embryo implantation, Pig as an animal model for obesity, Canine models of cancer, Bovine model for human ovarian diseases, Mutations in G protein-coupled receptors in large animals: Modeling human diseases, and more.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. xi 7. Chapter One: Sheep as a model for neuroendocrinology research - p. 1 8. Chapter Two: Relevance of dog as an animal model for urologic diseases - p. 37 9. Chapter Three: Canine models of human cancer: Bridging the gap to improve precision medicine - p. 67 10. Chapter Four: Bovine models for human ovarian diseases - p. 101 11. Chapter Five: Mutations in rhodopsin, endothelin B receptor, and CC chemokine receptor 5 in large animals: Modeling human diseases - p. 155 12. Chapter Six: Melanocortin-1 receptor mutations and pigmentation: Insights from large animals - p. 188 13. Chapter Seven: Mutations in melanocortin-4 receptor: From fish to men - p. 215 14. Chapter Eight: Patient-derived organoids as a model for tumor research - p. 259 15. Index - p. 326
Large Animals as Models for Human Diseases, Volume 189 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of important topics, including Sheep as a model for neuroendocrinology research, Relevance of dog as a model for urologic diseases, Relevance of lactocrine hypothesis to human maternal programming of development, Comparative aspects of embryo implantation, Pig as an animal model for obesity, Canine models of cancer, Bovine model for human ovarian diseases, Mutations in G protein-coupled receptors in large animals: Modeling human diseases, and more.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. xi 7. Chapter One: Sheep as a model for neuroendocrinology research - p. 1 8. Chapter Two: Relevance of dog as an animal model for urologic diseases - p. 37 9. Chapter Three: Canine models of human cancer: Bridging the gap to improve precision medicine - p. 67 10. Chapter Four: Bovine models for human ovarian diseases - p. 101 11. Chapter Five: Mutations in rhodopsin, endothelin B receptor, and CC chemokine receptor 5 in large animals: Modeling human diseases - p. 155 12. Chapter Six: Melanocortin-1 receptor mutations and pigmentation: Insights from large animals - p. 188 13. Chapter Seven: Mutations in melanocortin-4 receptor: From fish to men - p. 215 14. Chapter Eight: Patient-derived organoids as a model for tumor research - p. 259 15. Index - p. 326
