Light, Molecules, Reaction and Health offers a comprehensive overview of health-related, light-based processes and systems, paying special attention to molecular photochemistry. Users of photochemical methods and concepts in pharmacology and biomedicine will find detailed information on the basic processes underlying the biological effects of natural and artificial light—from the primary absorption event occurring in an endogenous or exogenous molecule in a biological compartment, to the final pathological or beneficial outcome. By emphasizing novel methods, including nanostructured materials in therapy and diagnostics, this book allows readers to critically interpret existing data with a goal of stimulating new research in phytotherapy and phytomedicine.
1. Cover image - p. Cover 2. Title page - p. iii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Dedication - p. v 6. Preface - p. ix 7. Chapter 1. Health and light - p. 1 8. Chapter 2. Interaction with the environment: Skin - p. 29 9. Abstract - p. 29 10. 2.1 Light in the environment - p. 29 11. 2.2 Microanatomy of the skin - p. 31 12. 2.3 Interaction between light and skin - p. 35 13. 2.4 Natural skin protection and tanning: melanogenesis - p. 39 14. 2.5 Artificial skin protection - p. 44 15. 2.6 Light effect on hair and teeth - p. 54 16. 2.7 Role of previtamin D - p. 57 17. 2.8 Vitamin D synthesis in the skin: friend or foe - p. 58 18. 2.9 Vitamin D and the immunological system - p. 64 19. 2.10 Ultraviolet light effect involving molecules different from vitamin D - p. 65 20. 2.11 Skin diseases caused by light - p. 68 21. 2.12 Skin photoaging and the role of free radicals - p. 69 22. 2.13 Enzymatic antioxidants - p. 75 23. 2.14 Nonenzymatic antioxidants - p. 76 24. 2.15 Antioxidants action against age-related diseases - p. 80 25. 2.16 Skin cancer - p. 90 26. 2.17 DNA photochemistry - p. 94 27. 2.18 DNA repair mechanism - p. 96 28. 2.19 Implications for mutagenesis - p. 107 29. 2.20 Skin catabolism - p. 111 30. 2.21 Autoimmune diseases - p. 120 31. References - p. 132 32. Chapter 3. Contact with the environment: sight - p. 149 33. Abstract - p. 149 34. 3.1 Theory of light and colors: historic aspects - p. 149 35. 3.2 Theory of colors and light: linguistic aspects - p. 153 36. 3.3 Newton’s theory of vision - p. 157 37. 3.4 The eye - p. 165 38. 3.5 Chemistry of vision - p. 193 39. 3.6 Sight in nonhumans - p. 200 40. 3.7 Accessory structures of the eye - p. 209 41. 3.8 Damage caused by light - p. 211 42. 3.9 Physical aspects - p. 215 43. 3.10 Vision impairment - p. 220 44. References - p. 222 45. Further reading - p. 222 46. Chapter 4. Circadian system - p. 229 47. Chapter 5. (Photo)chemotherapeutic - p. 247 48. Chapter 6. Oxidations - p. 297 49. Chapter 7. Emission - p. 313 50. Chapter 8. Conclusion and outlook - p. 329 51. Index - p. 337
Light, Molecules, Reaction and Health offers a comprehensive overview of health-related, light-based processes and systems, paying special attention to molecular photochemistry. Users of photochemical methods and concepts in pharmacology and biomedicine will find detailed information on the basic processes underlying the biological effects of natural and artificial light—from the primary absorption event occurring in an endogenous or exogenous molecule in a biological compartment, to the final pathological or beneficial outcome. By emphasizing novel methods, including nanostructured materials in therapy and diagnostics, this book allows readers to critically interpret existing data with a goal of stimulating new research in phytotherapy and phytomedicine.
1. Cover image - p. Cover 2. Title page - p. iii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Dedication - p. v 6. Preface - p. ix 7. Chapter 1. Health and light - p. 1 8. Chapter 2. Interaction with the environment: Skin - p. 29 9. Abstract - p. 29 10. 2.1 Light in the environment - p. 29 11. 2.2 Microanatomy of the skin - p. 31 12. 2.3 Interaction between light and skin - p. 35 13. 2.4 Natural skin protection and tanning: melanogenesis - p. 39 14. 2.5 Artificial skin protection - p. 44 15. 2.6 Light effect on hair and teeth - p. 54 16. 2.7 Role of previtamin D - p. 57 17. 2.8 Vitamin D synthesis in the skin: friend or foe - p. 58 18. 2.9 Vitamin D and the immunological system - p. 64 19. 2.10 Ultraviolet light effect involving molecules different from vitamin D - p. 65 20. 2.11 Skin diseases caused by light - p. 68 21. 2.12 Skin photoaging and the role of free radicals - p. 69 22. 2.13 Enzymatic antioxidants - p. 75 23. 2.14 Nonenzymatic antioxidants - p. 76 24. 2.15 Antioxidants action against age-related diseases - p. 80 25. 2.16 Skin cancer - p. 90 26. 2.17 DNA photochemistry - p. 94 27. 2.18 DNA repair mechanism - p. 96 28. 2.19 Implications for mutagenesis - p. 107 29. 2.20 Skin catabolism - p. 111 30. 2.21 Autoimmune diseases - p. 120 31. References - p. 132 32. Chapter 3. Contact with the environment: sight - p. 149 33. Abstract - p. 149 34. 3.1 Theory of light and colors: historic aspects - p. 149 35. 3.2 Theory of colors and light: linguistic aspects - p. 153 36. 3.3 Newton’s theory of vision - p. 157 37. 3.4 The eye - p. 165 38. 3.5 Chemistry of vision - p. 193 39. 3.6 Sight in nonhumans - p. 200 40. 3.7 Accessory structures of the eye - p. 209 41. 3.8 Damage caused by light - p. 211 42. 3.9 Physical aspects - p. 215 43. 3.10 Vision impairment - p. 220 44. References - p. 222 45. Further reading - p. 222 46. Chapter 4. Circadian system - p. 229 47. Chapter 5. (Photo)chemotherapeutic - p. 247 48. Chapter 6. Oxidations - p. 297 49. Chapter 7. Emission - p. 313 50. Chapter 8. Conclusion and outlook - p. 329 51. Index - p. 337
