Lipid in Pulmonary Drug Delivery explores the most recent advancements, strategies, and state-of-the-art technological progress in the development of lipid-based nanocarriers for pulmonary administration. The book presents wide coverage of various lipid-based nano-drug carriers such as liposomes, solid lipid nanoparticles, and nanoemulsions intended for the administration of drugs through the pulmonary route to treat different conditions. It also includes a general description of the formulation aspects of various lipid-based drug delivery vehicles, post-production processing, and biofate aspects with special emphasis on the pulmonary microenvironment.
In addition, the authors include an update on the clinical status of the potential lipid nanocarriers used for effective management of the pulmonary related diseases. Written in a technical way covering the latest advancements in lipid-based drug delivery for pulmonary administration, this book is a useful reference for researchers, scientists, and graduate and postgraduate students working on, or planning, research in the field of lipid-based nano-drug pulmonary delivery platforms.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Dedication - p. v 7. Contributors - p. xiii 8. About the editors - p. xvii 9. Preface - p. xix 10. Acknowledgments - p. xxi 11. Chapter 1. Lipid nanotechnology - p. 1 12. Chapter 2. Current scenario and challenges of lipid-based nanomedicines for pulmonary drug delivery - p. 21 13. Chapter 3. Effect of environment of the respiratory tract on nanomedicine drug delivery - p. 49 14. Chapter 4. Aerodynamics and deposition of lipid-based nanocarriers in the lungs - p. 69 15. Chapter 5. Liposome as a versatile carrier for pulmonary drug delivery - p. 85 16. Chapter 6. Advancements in nanostructured lipid carriers as drug delivery vehicles in the lungs - p. 105 17. Chapter 7. Solid lipid nanoparticles: A potential drug carrier in pulmonary system - p. 121 18. Chapter 8. Insights and applications of nanoemulsions as a drug carrier in lungs - p. 133 19. Chapter 9. Lipid-based drug delivery for lungs cancer - p. 153 20. Chapter 10. Exploring the state-of-art of lipid nanomedicines for obstructive pulmonary diseases - p. 191 21. Chapter 11. Lipid-based drug delivery for pulmonary microbial infections - p. 233 22. Chapter 12. Lipid-based drug delivery for systemic effect through pulmonary route of administration - p. 255 23. Chapter 13. Biofate of lipid-based nanomedicine after pulmonary administration - p. 301 24. Chapter 14. Surface modification of lipid based drug delivery for lungs - p. 319 25. Chapter 15. Evaluation of lipid-based formulation for pulmonary delivery - p. 337 26. Chapter 16. Physicochemical stability of lipid based nanocarriers in aerosol formulation - p. 353 27. Chapter 17. Translation of lipid based formulation for pulmonary drug delivery system: Clinical status - p. 371 28. Chapter 18. Regulatory aspects of lipid-based nanomedicine for pulmonary applications - p. 397 29. Chapter 19. Lipid-based vaccines against viruses including COVID-19 - p. 409 30. Chapter 20. Lipid-based nanocarriers in management of cystic fibrosis: A pulmonary complication - p. 435 31. Chapter 21. Pulmonary drug delivery of lipid-based formulations via nebulizers - p. 449 32. Chapter 22. Lipid-based peptide and gene delivery to lungs - p. 491 33. Index - p. 511
Lipid in Pulmonary Drug Delivery explores the most recent advancements, strategies, and state-of-the-art technological progress in the development of lipid-based nanocarriers for pulmonary administration. The book presents wide coverage of various lipid-based nano-drug carriers such as liposomes, solid lipid nanoparticles, and nanoemulsions intended for the administration of drugs through the pulmonary route to treat different conditions. It also includes a general description of the formulation aspects of various lipid-based drug delivery vehicles, post-production processing, and biofate aspects with special emphasis on the pulmonary microenvironment.
In addition, the authors include an update on the clinical status of the potential lipid nanocarriers used for effective management of the pulmonary related diseases. Written in a technical way covering the latest advancements in lipid-based drug delivery for pulmonary administration, this book is a useful reference for researchers, scientists, and graduate and postgraduate students working on, or planning, research in the field of lipid-based nano-drug pulmonary delivery platforms.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Dedication - p. v 7. Contributors - p. xiii 8. About the editors - p. xvii 9. Preface - p. xix 10. Acknowledgments - p. xxi 11. Chapter 1. Lipid nanotechnology - p. 1 12. Chapter 2. Current scenario and challenges of lipid-based nanomedicines for pulmonary drug delivery - p. 21 13. Chapter 3. Effect of environment of the respiratory tract on nanomedicine drug delivery - p. 49 14. Chapter 4. Aerodynamics and deposition of lipid-based nanocarriers in the lungs - p. 69 15. Chapter 5. Liposome as a versatile carrier for pulmonary drug delivery - p. 85 16. Chapter 6. Advancements in nanostructured lipid carriers as drug delivery vehicles in the lungs - p. 105 17. Chapter 7. Solid lipid nanoparticles: A potential drug carrier in pulmonary system - p. 121 18. Chapter 8. Insights and applications of nanoemulsions as a drug carrier in lungs - p. 133 19. Chapter 9. Lipid-based drug delivery for lungs cancer - p. 153 20. Chapter 10. Exploring the state-of-art of lipid nanomedicines for obstructive pulmonary diseases - p. 191 21. Chapter 11. Lipid-based drug delivery for pulmonary microbial infections - p. 233 22. Chapter 12. Lipid-based drug delivery for systemic effect through pulmonary route of administration - p. 255 23. Chapter 13. Biofate of lipid-based nanomedicine after pulmonary administration - p. 301 24. Chapter 14. Surface modification of lipid based drug delivery for lungs - p. 319 25. Chapter 15. Evaluation of lipid-based formulation for pulmonary delivery - p. 337 26. Chapter 16. Physicochemical stability of lipid based nanocarriers in aerosol formulation - p. 353 27. Chapter 17. Translation of lipid based formulation for pulmonary drug delivery system: Clinical status - p. 371 28. Chapter 18. Regulatory aspects of lipid-based nanomedicine for pulmonary applications - p. 397 29. Chapter 19. Lipid-based vaccines against viruses including COVID-19 - p. 409 30. Chapter 20. Lipid-based nanocarriers in management of cystic fibrosis: A pulmonary complication - p. 435 31. Chapter 21. Pulmonary drug delivery of lipid-based formulations via nebulizers - p. 449 32. Chapter 22. Lipid-based peptide and gene delivery to lungs - p. 491 33. Index - p. 511