Loomis's Essentials of Toxicology, Fifth Edition, provides the information on the harmful biologic effects associated with exposures to chemicals of all types. The scope of this book includes a discussion of the major types of chemicals involved, their general properties and detrimental biologic effects, the methods used to demonstrate these effects, the basis for clinical diagnosis, and therapy for the harmful effects of chemicals on humans. Individual examples are used to demonstrate the principle discussed. This reference volume will be an invaluable resource for both toxicologists and graduate and advanced undergraduate students in toxicology and public health.
1. Chapter 1: Introduction, scope, and principles - p. xi 2. Chapter 2: Dose and dose-response relationships in toxicology - p. 15 3. Chapter 3: Biologic factors that influence toxicity - p. 31 4. Chapter 4: Chemical factors that influence toxicity - p. 44 5. Chapter 5: Influence of route of administration on systemic toxicity - p. 59 6. Chapter 6: Genetic factors that influence toxicity - p. 75 7. Chapter 7: Classification of harmful effects of chemicals - p. 92 8. Chapter 8: Toxic effects of chemicals - p. 97 9. Chapter 9: Abnormal response to chemicals - p. 110 10. Chapter 10: The basis of selective toxicity - p. 123 11. Chapter 11: The basis of antidotal therapy - p. 131 12. Chapter 12: Principles of biological tests for toxicity - p. 151 13. Chapter 13: Toxicologic testing methods - p. 187 14. Chapter 14: Clinical toxicology - p. 222 15. Chapter 15: Information sources in toxicology - p. 232 16. Index - p. 249
Loomis's Essentials of Toxicology, Fifth Edition, provides the information on the harmful biologic effects associated with exposures to chemicals of all types. The scope of this book includes a discussion of the major types of chemicals involved, their general properties and detrimental biologic effects, the methods used to demonstrate these effects, the basis for clinical diagnosis, and therapy for the harmful effects of chemicals on humans. Individual examples are used to demonstrate the principle discussed. This reference volume will be an invaluable resource for both toxicologists and graduate and advanced undergraduate students in toxicology and public health.
1. Chapter 1: Introduction, scope, and principles - p. xi 2. Chapter 2: Dose and dose-response relationships in toxicology - p. 15 3. Chapter 3: Biologic factors that influence toxicity - p. 31 4. Chapter 4: Chemical factors that influence toxicity - p. 44 5. Chapter 5: Influence of route of administration on systemic toxicity - p. 59 6. Chapter 6: Genetic factors that influence toxicity - p. 75 7. Chapter 7: Classification of harmful effects of chemicals - p. 92 8. Chapter 8: Toxic effects of chemicals - p. 97 9. Chapter 9: Abnormal response to chemicals - p. 110 10. Chapter 10: The basis of selective toxicity - p. 123 11. Chapter 11: The basis of antidotal therapy - p. 131 12. Chapter 12: Principles of biological tests for toxicity - p. 151 13. Chapter 13: Toxicologic testing methods - p. 187 14. Chapter 14: Clinical toxicology - p. 222 15. Chapter 15: Information sources in toxicology - p. 232 16. Index - p. 249
