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Authored by experienced surgeons and key innovators in the fast-moving field of LIF surgery, Lumbar Interbody Fusions provides an in-depth, focused approach to recent advances in surgical techniques and technology. Covering both minimally invasive and open procedures, this comprehensive reference provides step-by-step details for proven techniques, including extreme lateral, oblique lateral, and direct lateral approaches; intertransverse approaches; axial approaches; and endoscopic approaches.

  • Focuses on the technical nuances, pearls and pitfalls of each procedure, as well as complication avoidance and management.
  • Features high-quality radiographs and intraoperative images for superb visual guidance throughout.
  • Covers topics that have as-yet unsettled surgical management, such as thoracolumbar and lumbosacral overlap diseases.
  • Includes a concise review of evidence-based spine literature at the end of each procedural chapter.
  • Features chapters on adjunct instrumentation such as pedicle screw and facet fixation, as well as graft selection and revision surgeries.

1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Dedication - p. iii 6. Contributors - p. iii 7. Preface - p. iii 8. Virtual Microscope Slide List - p. iii 9. Part I: Molecular and Cellular Basis of Hematology - p. iii 10. List of Illustrations - p. iii 11. List of Tables - p. iii 12. Chapter 1: Anatomy and Physiology of the Gene - p. iii 13. Chapter 2: Epigenetics and Epigenomics - p. iii 14. Chapter 3: Genomic Approaches to Hematology - p. iii 15. Chapter 4: Regulation of Gene Expression, Transcription, Splicing, and RNA Metabolism - p. iii 16. Chapter 5: Protein Synthesis, Processing, and Trafficking - p. iii 17. Chapter 6: Protein Architecture: Relationship of Form and Function - p. iii 18. Chapter 7: Signaling Transduction and Metabolomics - p. iii 19. Chapter 8: Pharmacogenomics and Hematologic Diseases - p. iii 20. Part II: Cellular Basis of Hematology - p. iii 21. Chapter 9: Hematopoietic Stem Cell Biology - p. iii 22. Chapter 10: Stem Cell Model of Hematologic Diseases - p. iii 23. Chapter 11: Hematopoietic Microenvironment - p. iii 24. Chapter 12: Cell Adhesion - p. iii 25. Chapter 13: Chemokines and Hematopoietic Cell Trafficking - p. iii 26. Chapter 14: Interactions Between Hematopoietic Stem and Progenitor Cells and the Bone Marrow: Current Biology of Stem Cell Homing and Mobilization - p. iii 27. Chapter 15: Vascular Growth in Health and Disease - p. iii 28. Chapter 16: Cytokine/Receptor Families and Signal Transduction - p. iii 29. Chapter 17: Control of Cell Division - p. iii 30. Chapter 18: Cell Death - p. iii 31. Part III: Immunologic Basis of Hematology - p. iii 32. Chapter 19: Overview and Compartmentalization of the Immune System - p. iii 33. Chapter 20: B-Cell Development - p. iii 34. Chapter 21: T-Cell Immunity - p. iii 35. Chapter 22: Natural Killer Cell Immunity - p. iii 36. Chapter 23: Dendritic Cell Biology - p. iii 37. Chapter 24: Complement and Immunoglobulin Biology Leading to Clinical Translation - p. iii 38. Chapter 25: Tolerance and Autoimmunity - p. iii 39. Part IV: Disorders of Hematopoietic Cell Development - p. iii 40. Chapter 26: Biology of Erythropoiesis, Erythroid Differentiation, and Maturation - p. iii 41. Chapter 27: Granulocytopoiesis and Monocytopoiesis - p. iii 42. Chapter 28: Thrombocytopoiesis - p. iii 43. Chapter 29: Inherited Bone Marrow Failure Syndromes - p. iii 44. Chapter 30: Aplastic Anemia - p. iii 45. Chapter 31: Paroxysmal Nocturnal Hemoglobinuria - p. iii 46. Chapter 32: Acquired Disorders of Red Cell, White Cell, and Platelet Production - p. iii 47. Part V: Red Blood Cells - p. iii 48. Chapter 33: Pathobiology of the Human Erythrocyte and Its Hemoglobins - p. iii 49. Chapter 34: Approach to Anemia in the Adult and Child - p. iii 50. Chapter 35: Pathophysiology of Iron Homeostasis - p. iii 51. Chapter 36: Disorders of Iron Homeostasis: Iron Deficiency and Overload - p. iii 52. Chapter 37: Anemia of Chronic Diseases - p. iii 53. Chapter 38: Heme Biosynthesis and Its Disorders: Porphyrias and Sideroblastic Anemias - p. iii 54. Chapter 39: Megaloblastic Anemias - p. iii 55. Chapter 40: Thalassemia Syndromes - p. iii 56. Chapter 41: Pathobiology of Sickle Cell Disease - p. iii 57. Chapter 42: Sickle Cell Disease: Clinical Features and Management - p. iii 58. Chapter 43: Hemoglobin Variants Associated With Hemolytic Anemia, Altered Oxygen Affinity, and Methemoglobinemias - p. iii 59. Chapter 44: Red Blood Cell Enzymopathies - p. iii 60. Chapter 45: Red Blood Cell Membrane Disorders - p. iii 61. Chapter 46: Autoimmune Hemolytic Anemia - p. iii 62. Chapter 47: Extrinsic Nonimmune Hemolytic Anemias - p. iii 63. Part VI: Non-Malignant Leukocytes - p. iii 64. Chapter 48: Neutrophilic Leukocytosis, Neutropenia, Monocytosis, and Monocytopenia - p. iii 65. Chapter 49: Lymphocytosis, Lymphocytopenia, Hypergammaglobulinemia, and Hypogammaglobulinemia - p. iii 66. Chapter 50: Disorders of Phagocyte Function - p. iii 67. Chapter 51: Congenital Disorders of Lymphocyte Function - p. iii 68. Chapter 52: Histiocytic Disorders - p. iii 69. Chapter 53: Lysosomal Storage Diseases: Perspectives and Principles - p. iii 70. Chapter 54: Infectious Mononucleosis and Other Epstein-Barr Virus–Associated Diseases - p. iii 71. Part VII: Hematologic Malignancies - p. iii 72. Chapter 55: Progress in the Classification of Hematopoietic and Lymphoid Neoplasms: Clinical Implications - p. iii 73. Chapter 56: Conventional and Molecular Cytogenomic Basis of Hematologic Malignancies - p. iii 74. Chapter 57: Pharmacology and Molecular Mechanisms of Antineoplastic Agents for Hematologic Malignancies - p. iii 75. Chapter 58: Pathobiology of Acute Myeloid Leukemia - p. iii 76. Chapter 59: Clinical Manifestations and Treatment of Acute Myeloid Leukemia - p. iii 77. Chapter 60: Myelodysplastic Syndromes - p. iii 78. Chapter 61: Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome in Adults - p. iii 79. Chapter 62: Acute Myeloid Leukemia in Children - p. iii 80. Chapter 63: Myelodysplastic Syndromes and Myeloproliferative Neoplasms in Children - p. iii 81. Chapter 64: Pathobiology of Acute Lymphoblastic Leukemia - p. iii 82. Chapter 65: Clinical Manifestations and Treatment of Childhood Acute Lymphoblastic Leukemia - p. iii 83. Chapter 66: Acute Lymphoblastic Leukemia in Adults - p. iii 84. Chapter 67: Chronic Myeloid Leukemia - p. iii 85. Chapter 68: The Polycythemias - p. iii 86. Chapter 69: Essential Thrombocythemia - p. iii 87. Chapter 70: Primary Myelofibrosis - p. iii 88. Chapter 71: Eosinophilia, Eosinophil-Associated Diseases, Eosinophilic Leukemias, and the Hypereosinophilic Syndromes - p. iii 89. Chapter 72: Mast Cells and Mastocytosis - p. iii 90. Chapter 73: The Pathologic Basis for the Classification of Non-Hodgkin and Hodgkin Lymphomas - p. iii 91. Chapter 74: Origin of Hodgkin Lymphoma - p. iii 92. Chapter 75: Hodgkin Lymphoma: Clinical Manifestations, Staging, and Therapy - p. iii 93. Chapter 76: Origin of Non-Hodgkin Lymphoma - p. iii 94. Chapter 77: Chronic Lymphocytic Leukemia - p. iii 95. Chapter 78: Hairy Cell Leukemia - p. iii 96. Chapter 79: Marginal Zone Lymphomas (Extranodal/Malt, Splenic, and Nodal) - p. iii 97. Chapter 80: Clinical Manifestations, Staging, and Treatment of Follicular Lymphoma - p. iii 98. Chapter 81: Mantle Cell Lymphoma - p. iii 99. Chapter 82: Diagnosis and Treatment of Diffuse Large B-Cell Lymphoma and Burkitt Lymphoma - p. iii 100. Chapter 83: Virus-Associated Lymphoma - p. iii 101. Chapter 84: Malignant Lymphomas in Childhood - p. iii 102. Chapter 85: T-Cell Lymphomas - p. iii 103. Chapter 86: Plasma Cell Neoplasms - p. iii 104. Chapter 87: Waldenström Macroglobulinemia/Lymphoplasmacytic Lymphoma - p. iii 105. Chapter 88: Immunoglobulin Light Chain Amyloidosis (Primary Amyloidosis) - p. iii 106. Part VIII: Comprehensive Care of Patients with Hematologic Malignancies - p. iii 107. Chapter 89: Clinical Approach to Infections in the Compromised Host - p. iii 108. Chapter 90: Psychosocial Aspects of Hematologic Disorders - p. iii 109. Chapter 91: Pain Management and Antiemetic Therapy in Hematologic Disorders - p. iii 110. Chapter 92: Palliative Care - p. iii 111. Chapter 93: Late Complications of Hematologic Diseases and Their Therapies - p. iii 112. Part IX: Cell-Based Therapies - p. iii 113. Chapter 94: Overview and Historical Perspective of Current Cell-Based Therapies - p. iii 114. Chapter 95: Practical Aspects of Hematologic Stem Cell Harvesting and Mobilization - p. iii 115. Chapter 96: Investigational New Drug–Enabling Processes for Cell-Based Therapies - p. iii 116. Chapter 97: Graft Engineering and Cell Processing - p. iii 117. Chapter 98: Principles of Cell-Based Genetic Therapies - p. iii 118. Chapter 99: Mesenchymal Stromal Cells - p. iii 119. Chapter 100: T-Cell Therapy of Hematologic Diseases - p. iii 120. Chapter 101: Natural Killer Cell–Based Therapies - p. iii 121. Chapter 102: Immune Checkpoint Blockade in Hematologic Malignancies - p. iii 122. Part X: Transplantation - p. iii 123. Chapter 103: Overview and Choice of Donor of Hematopoietic Stem Cell Transplantation - p. iii 124. Chapter 104: Indications and Outcomes of Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancies in Adults - p. iii 125. Chapter 105: Unrelated Donor Hematopoietic Cell Transplantation - p. iii 126. Chapter 106: Haploidentical Hematopoietic Cell Transplantation - p. iii 127. Chapter 107: Unrelated Donor Cord Blood Transplantation for Hematologic Malignancies - p. iii 128. Chapter 108: Graft-Versus-Host Disease and Graft-Versus-Leukemia Responses - p. iii 129. Chapter 109: Complications After Hematopoietic Cell Transplantation - p. iii 130. Part XI: Transfusion Medicine - p. iii 131. Chapter 110: Human Blood Group Antigens and Antibodies - p. iii 132. Chapter 111: Principles of Red Blood Cell Transfusion - p. iii 133. Chapter 112: Clinical Considerations in Platelet Transfusion Therapy - p. iii 134. Chapter 113: Human Leukocyte Antigen and Human Neutrophil Antigen Systems - p. iii 135. Chapter 114: Principles of Neutrophil (Granulocyte) Transfusions - p. iii 136. Chapter 115: Transfusion of Plasma and Plasma Derivatives: Plasma, Cryoprecipitate, Albumin, and Immunoglobulins - p. iii 137. Chapter 116: Preparation of Plasma-Derived and Recombinant Human Plasma Proteins - p. iii 138. Chapter 117: Transfusion Therapy for Coagulation Factor Deficiencies - p. iii 139. Chapter 118: Hemapheresis - p. iii 140. Chapter 119: Transfusion Reactions to Blood and Cell Therapy Products - p. iii 141. Chapter 120: Transfusion-Transmitted Diseases - p. iii 142. Chapter 121: Pediatric Transfusion Medicine - p. iii 143. Part XII: Hemostasis and Thrombosis - p. iii 144. Chapter 122: Overview of Hemostasis and Thrombosis - p. iii 145. Chapter 123: The Blood Vessel Wall - p. iii 146. Chapter 124: Megakaryocyte and Platelet Structure - p. iii 147. Chapter 125: Molecular Basis of Platelet Function - p. iii 148. Chapter 126: Molecular Basis of Blood Coagulation - p. iii 149. Chapter 127: Regulatory Mechanisms in Hemostasis - p. iii 150. Chapter 128: Clinical Approach to the Patient With Bleeding or Bruising - p. iii 151. Chapter 129: Laboratory Evaluation of Hemostatic and Thrombotic Disorders - p. iii 152. Chapter 130: Acquired Disorders of Platelet Function - p. iii 153. Chapter 131: Diseases of Platelet Number: Immune Thrombocytopenia, Neonatal Alloimmune Thrombocytopenia, and Posttransfusion Purpura - p. iii 154. Chapter 132: Thrombocytopenia Caused by Platelet Destruction, Hypersplenism, or Hemodilution - p. iii 155. Chapter 133: Heparin-Induced Thrombocytopenia - p. iii 156. Chapter 134: Thrombotic Thrombocytopenic Purpura and the Hemolytic Uremic Syndromes - p. iii 157. Chapter 135: Hemophilia A and B - p. iii 158. Chapter 136: Inhibitors in Hemophilias - p. iii 159. Chapter 137: Rare Coagulation Factor Deficiencies - p. iii 160. Chapter 138: Structure, Biology, and Genetics of von Willebrand Factor - p. iii 161. Chapter 139: Disseminated Intravascular Coagulation - p. iii 162. Chapter 140: Hypercoagulable States - p. iii 163. Chapter 141: The Antiphospholipid Syndrome - p. iii 164. Chapter 142: Venous Thromboembolism - p. iii 165. Chapter 143: Mechanical Interventions in Arterial and Venous Thrombosis - p. iii 166. Chapter 144: Atherothrombosis - p. iii 167. Chapter 145: Stroke - p. iii 168. Chapter 146: Acute Coronary Syndromes - p. iii 169. Chapter 147: Atrial Fibrillation - p. iii 170. Chapter 148: Peripheral Artery Disease - p. iii 171. Chapter 149: Antithrombotic Drugs - p. iii 172. Chapter 150: Disorders of Coagulation in the Neonate - p. iii 173. Part XIII: Consultative Hematology - p. iii 174. Chapter 151: Hematologic Changes in Pregnancy - p. iii 175. Chapter 152: Hematologic Manifestations of Childhood Illness - p. iii 176. Chapter 153: Hematologic Manifestations of Liver Disease - p. iii 177. Chapter 154: Hematologic Manifestations of Renal Disease - p. iii 178. Chapter 155: Hematologic Manifestations of Malignancy - p. iii 179. Chapter 156: Integrative Therapies in Patients With Hematologic Diseases - p. iii 180. Chapter 157: Hematologic Manifestations of HIV/AIDS - p. iii 181. Chapter 158: Hematologic Aspects of Parasitic Diseases - p. iii 182. Chapter 159: Hematologic Problems in the Surgical Patient: Bleeding and Thrombosis - p. iii 183. Chapter 160: The Spleen and Its Disorders - p. iii 184. Chapter 161: Hematology in Aging - p. iii 185. Chapter 162: Resources for the Hematologist: Interpretive Comments and Selected Reference Values for Neonatal, Pediatric, and Adult Populations - p. iii 186. Index - p. iii

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Descripción

Authored by experienced surgeons and key innovators in the fast-moving field of LIF surgery, Lumbar Interbody Fusions provides an in-depth, focused approach to recent advances in surgical techniques and technology. Covering both minimally invasive and open procedures, this comprehensive reference provides step-by-step details for proven techniques, including extreme lateral, oblique lateral, and direct lateral approaches; intertransverse approaches; axial approaches; and endoscopic approaches.

  • Focuses on the technical nuances, pearls and pitfalls of each procedure, as well as complication avoidance and management.
  • Features high-quality radiographs and intraoperative images for superb visual guidance throughout.
  • Covers topics that have as-yet unsettled surgical management, such as thoracolumbar and lumbosacral overlap diseases.
  • Includes a concise review of evidence-based spine literature at the end of each procedural chapter.
  • Features chapters on adjunct instrumentation such as pedicle screw and facet fixation, as well as graft selection and revision surgeries.

1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Dedication - p. iii 6. Contributors - p. iii 7. Preface - p. iii 8. Virtual Microscope Slide List - p. iii 9. Part I: Molecular and Cellular Basis of Hematology - p. iii 10. List of Illustrations - p. iii 11. List of Tables - p. iii 12. Chapter 1: Anatomy and Physiology of the Gene - p. iii 13. Chapter 2: Epigenetics and Epigenomics - p. iii 14. Chapter 3: Genomic Approaches to Hematology - p. iii 15. Chapter 4: Regulation of Gene Expression, Transcription, Splicing, and RNA Metabolism - p. iii 16. Chapter 5: Protein Synthesis, Processing, and Trafficking - p. iii 17. Chapter 6: Protein Architecture: Relationship of Form and Function - p. iii 18. Chapter 7: Signaling Transduction and Metabolomics - p. iii 19. Chapter 8: Pharmacogenomics and Hematologic Diseases - p. iii 20. Part II: Cellular Basis of Hematology - p. iii 21. Chapter 9: Hematopoietic Stem Cell Biology - p. iii 22. Chapter 10: Stem Cell Model of Hematologic Diseases - p. iii 23. Chapter 11: Hematopoietic Microenvironment - p. iii 24. Chapter 12: Cell Adhesion - p. iii 25. Chapter 13: Chemokines and Hematopoietic Cell Trafficking - p. iii 26. Chapter 14: Interactions Between Hematopoietic Stem and Progenitor Cells and the Bone Marrow: Current Biology of Stem Cell Homing and Mobilization - p. iii 27. Chapter 15: Vascular Growth in Health and Disease - p. iii 28. Chapter 16: Cytokine/Receptor Families and Signal Transduction - p. iii 29. Chapter 17: Control of Cell Division - p. iii 30. Chapter 18: Cell Death - p. iii 31. Part III: Immunologic Basis of Hematology - p. iii 32. Chapter 19: Overview and Compartmentalization of the Immune System - p. iii 33. Chapter 20: B-Cell Development - p. iii 34. Chapter 21: T-Cell Immunity - p. iii 35. Chapter 22: Natural Killer Cell Immunity - p. iii 36. Chapter 23: Dendritic Cell Biology - p. iii 37. Chapter 24: Complement and Immunoglobulin Biology Leading to Clinical Translation - p. iii 38. Chapter 25: Tolerance and Autoimmunity - p. iii 39. Part IV: Disorders of Hematopoietic Cell Development - p. iii 40. Chapter 26: Biology of Erythropoiesis, Erythroid Differentiation, and Maturation - p. iii 41. Chapter 27: Granulocytopoiesis and Monocytopoiesis - p. iii 42. Chapter 28: Thrombocytopoiesis - p. iii 43. Chapter 29: Inherited Bone Marrow Failure Syndromes - p. iii 44. Chapter 30: Aplastic Anemia - p. iii 45. Chapter 31: Paroxysmal Nocturnal Hemoglobinuria - p. iii 46. Chapter 32: Acquired Disorders of Red Cell, White Cell, and Platelet Production - p. iii 47. Part V: Red Blood Cells - p. iii 48. Chapter 33: Pathobiology of the Human Erythrocyte and Its Hemoglobins - p. iii 49. Chapter 34: Approach to Anemia in the Adult and Child - p. iii 50. Chapter 35: Pathophysiology of Iron Homeostasis - p. iii 51. Chapter 36: Disorders of Iron Homeostasis: Iron Deficiency and Overload - p. iii 52. Chapter 37: Anemia of Chronic Diseases - p. iii 53. Chapter 38: Heme Biosynthesis and Its Disorders: Porphyrias and Sideroblastic Anemias - p. iii 54. Chapter 39: Megaloblastic Anemias - p. iii 55. Chapter 40: Thalassemia Syndromes - p. iii 56. Chapter 41: Pathobiology of Sickle Cell Disease - p. iii 57. Chapter 42: Sickle Cell Disease: Clinical Features and Management - p. iii 58. Chapter 43: Hemoglobin Variants Associated With Hemolytic Anemia, Altered Oxygen Affinity, and Methemoglobinemias - p. iii 59. Chapter 44: Red Blood Cell Enzymopathies - p. iii 60. Chapter 45: Red Blood Cell Membrane Disorders - p. iii 61. Chapter 46: Autoimmune Hemolytic Anemia - p. iii 62. Chapter 47: Extrinsic Nonimmune Hemolytic Anemias - p. iii 63. Part VI: Non-Malignant Leukocytes - p. iii 64. Chapter 48: Neutrophilic Leukocytosis, Neutropenia, Monocytosis, and Monocytopenia - p. iii 65. Chapter 49: Lymphocytosis, Lymphocytopenia, Hypergammaglobulinemia, and Hypogammaglobulinemia - p. iii 66. Chapter 50: Disorders of Phagocyte Function - p. iii 67. Chapter 51: Congenital Disorders of Lymphocyte Function - p. iii 68. Chapter 52: Histiocytic Disorders - p. iii 69. Chapter 53: Lysosomal Storage Diseases: Perspectives and Principles - p. iii 70. Chapter 54: Infectious Mononucleosis and Other Epstein-Barr Virus–Associated Diseases - p. iii 71. Part VII: Hematologic Malignancies - p. iii 72. Chapter 55: Progress in the Classification of Hematopoietic and Lymphoid Neoplasms: Clinical Implications - p. iii 73. Chapter 56: Conventional and Molecular Cytogenomic Basis of Hematologic Malignancies - p. iii 74. Chapter 57: Pharmacology and Molecular Mechanisms of Antineoplastic Agents for Hematologic Malignancies - p. iii 75. Chapter 58: Pathobiology of Acute Myeloid Leukemia - p. iii 76. Chapter 59: Clinical Manifestations and Treatment of Acute Myeloid Leukemia - p. iii 77. Chapter 60: Myelodysplastic Syndromes - p. iii 78. Chapter 61: Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome in Adults - p. iii 79. Chapter 62: Acute Myeloid Leukemia in Children - p. iii 80. Chapter 63: Myelodysplastic Syndromes and Myeloproliferative Neoplasms in Children - p. iii 81. Chapter 64: Pathobiology of Acute Lymphoblastic Leukemia - p. iii 82. Chapter 65: Clinical Manifestations and Treatment of Childhood Acute Lymphoblastic Leukemia - p. iii 83. Chapter 66: Acute Lymphoblastic Leukemia in Adults - p. iii 84. Chapter 67: Chronic Myeloid Leukemia - p. iii 85. Chapter 68: The Polycythemias - p. iii 86. Chapter 69: Essential Thrombocythemia - p. iii 87. Chapter 70: Primary Myelofibrosis - p. iii 88. Chapter 71: Eosinophilia, Eosinophil-Associated Diseases, Eosinophilic Leukemias, and the Hypereosinophilic Syndromes - p. iii 89. Chapter 72: Mast Cells and Mastocytosis - p. iii 90. Chapter 73: The Pathologic Basis for the Classification of Non-Hodgkin and Hodgkin Lymphomas - p. iii 91. Chapter 74: Origin of Hodgkin Lymphoma - p. iii 92. Chapter 75: Hodgkin Lymphoma: Clinical Manifestations, Staging, and Therapy - p. iii 93. Chapter 76: Origin of Non-Hodgkin Lymphoma - p. iii 94. Chapter 77: Chronic Lymphocytic Leukemia - p. iii 95. Chapter 78: Hairy Cell Leukemia - p. iii 96. Chapter 79: Marginal Zone Lymphomas (Extranodal/Malt, Splenic, and Nodal) - p. iii 97. Chapter 80: Clinical Manifestations, Staging, and Treatment of Follicular Lymphoma - p. iii 98. Chapter 81: Mantle Cell Lymphoma - p. iii 99. Chapter 82: Diagnosis and Treatment of Diffuse Large B-Cell Lymphoma and Burkitt Lymphoma - p. iii 100. Chapter 83: Virus-Associated Lymphoma - p. iii 101. Chapter 84: Malignant Lymphomas in Childhood - p. iii 102. Chapter 85: T-Cell Lymphomas - p. iii 103. Chapter 86: Plasma Cell Neoplasms - p. iii 104. Chapter 87: Waldenström Macroglobulinemia/Lymphoplasmacytic Lymphoma - p. iii 105. Chapter 88: Immunoglobulin Light Chain Amyloidosis (Primary Amyloidosis) - p. iii 106. Part VIII: Comprehensive Care of Patients with Hematologic Malignancies - p. iii 107. Chapter 89: Clinical Approach to Infections in the Compromised Host - p. iii 108. Chapter 90: Psychosocial Aspects of Hematologic Disorders - p. iii 109. Chapter 91: Pain Management and Antiemetic Therapy in Hematologic Disorders - p. iii 110. Chapter 92: Palliative Care - p. iii 111. Chapter 93: Late Complications of Hematologic Diseases and Their Therapies - p. iii 112. Part IX: Cell-Based Therapies - p. iii 113. Chapter 94: Overview and Historical Perspective of Current Cell-Based Therapies - p. iii 114. Chapter 95: Practical Aspects of Hematologic Stem Cell Harvesting and Mobilization - p. iii 115. Chapter 96: Investigational New Drug–Enabling Processes for Cell-Based Therapies - p. iii 116. Chapter 97: Graft Engineering and Cell Processing - p. iii 117. Chapter 98: Principles of Cell-Based Genetic Therapies - p. iii 118. Chapter 99: Mesenchymal Stromal Cells - p. iii 119. Chapter 100: T-Cell Therapy of Hematologic Diseases - p. iii 120. Chapter 101: Natural Killer Cell–Based Therapies - p. iii 121. Chapter 102: Immune Checkpoint Blockade in Hematologic Malignancies - p. iii 122. Part X: Transplantation - p. iii 123. Chapter 103: Overview and Choice of Donor of Hematopoietic Stem Cell Transplantation - p. iii 124. Chapter 104: Indications and Outcomes of Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancies in Adults - p. iii 125. Chapter 105: Unrelated Donor Hematopoietic Cell Transplantation - p. iii 126. Chapter 106: Haploidentical Hematopoietic Cell Transplantation - p. iii 127. Chapter 107: Unrelated Donor Cord Blood Transplantation for Hematologic Malignancies - p. iii 128. Chapter 108: Graft-Versus-Host Disease and Graft-Versus-Leukemia Responses - p. iii 129. Chapter 109: Complications After Hematopoietic Cell Transplantation - p. iii 130. Part XI: Transfusion Medicine - p. iii 131. Chapter 110: Human Blood Group Antigens and Antibodies - p. iii 132. Chapter 111: Principles of Red Blood Cell Transfusion - p. iii 133. Chapter 112: Clinical Considerations in Platelet Transfusion Therapy - p. iii 134. Chapter 113: Human Leukocyte Antigen and Human Neutrophil Antigen Systems - p. iii 135. Chapter 114: Principles of Neutrophil (Granulocyte) Transfusions - p. iii 136. Chapter 115: Transfusion of Plasma and Plasma Derivatives: Plasma, Cryoprecipitate, Albumin, and Immunoglobulins - p. iii 137. Chapter 116: Preparation of Plasma-Derived and Recombinant Human Plasma Proteins - p. iii 138. Chapter 117: Transfusion Therapy for Coagulation Factor Deficiencies - p. iii 139. Chapter 118: Hemapheresis - p. iii 140. Chapter 119: Transfusion Reactions to Blood and Cell Therapy Products - p. iii 141. Chapter 120: Transfusion-Transmitted Diseases - p. iii 142. Chapter 121: Pediatric Transfusion Medicine - p. iii 143. Part XII: Hemostasis and Thrombosis - p. iii 144. Chapter 122: Overview of Hemostasis and Thrombosis - p. iii 145. Chapter 123: The Blood Vessel Wall - p. iii 146. Chapter 124: Megakaryocyte and Platelet Structure - p. iii 147. Chapter 125: Molecular Basis of Platelet Function - p. iii 148. Chapter 126: Molecular Basis of Blood Coagulation - p. iii 149. Chapter 127: Regulatory Mechanisms in Hemostasis - p. iii 150. Chapter 128: Clinical Approach to the Patient With Bleeding or Bruising - p. iii 151. Chapter 129: Laboratory Evaluation of Hemostatic and Thrombotic Disorders - p. iii 152. Chapter 130: Acquired Disorders of Platelet Function - p. iii 153. Chapter 131: Diseases of Platelet Number: Immune Thrombocytopenia, Neonatal Alloimmune Thrombocytopenia, and Posttransfusion Purpura - p. iii 154. Chapter 132: Thrombocytopenia Caused by Platelet Destruction, Hypersplenism, or Hemodilution - p. iii 155. Chapter 133: Heparin-Induced Thrombocytopenia - p. iii 156. Chapter 134: Thrombotic Thrombocytopenic Purpura and the Hemolytic Uremic Syndromes - p. iii 157. Chapter 135: Hemophilia A and B - p. iii 158. Chapter 136: Inhibitors in Hemophilias - p. iii 159. Chapter 137: Rare Coagulation Factor Deficiencies - p. iii 160. Chapter 138: Structure, Biology, and Genetics of von Willebrand Factor - p. iii 161. Chapter 139: Disseminated Intravascular Coagulation - p. iii 162. Chapter 140: Hypercoagulable States - p. iii 163. Chapter 141: The Antiphospholipid Syndrome - p. iii 164. Chapter 142: Venous Thromboembolism - p. iii 165. Chapter 143: Mechanical Interventions in Arterial and Venous Thrombosis - p. iii 166. Chapter 144: Atherothrombosis - p. iii 167. Chapter 145: Stroke - p. iii 168. Chapter 146: Acute Coronary Syndromes - p. iii 169. Chapter 147: Atrial Fibrillation - p. iii 170. Chapter 148: Peripheral Artery Disease - p. iii 171. Chapter 149: Antithrombotic Drugs - p. iii 172. Chapter 150: Disorders of Coagulation in the Neonate - p. iii 173. Part XIII: Consultative Hematology - p. iii 174. Chapter 151: Hematologic Changes in Pregnancy - p. iii 175. Chapter 152: Hematologic Manifestations of Childhood Illness - p. iii 176. Chapter 153: Hematologic Manifestations of Liver Disease - p. iii 177. Chapter 154: Hematologic Manifestations of Renal Disease - p. iii 178. Chapter 155: Hematologic Manifestations of Malignancy - p. iii 179. Chapter 156: Integrative Therapies in Patients With Hematologic Diseases - p. iii 180. Chapter 157: Hematologic Manifestations of HIV/AIDS - p. iii 181. Chapter 158: Hematologic Aspects of Parasitic Diseases - p. iii 182. Chapter 159: Hematologic Problems in the Surgical Patient: Bleeding and Thrombosis - p. iii 183. Chapter 160: The Spleen and Its Disorders - p. iii 184. Chapter 161: Hematology in Aging - p. iii 185. Chapter 162: Resources for the Hematologist: Interpretive Comments and Selected Reference Values for Neonatal, Pediatric, and Adult Populations - p. iii 186. Index - p. iii

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