Over the past 50 years, more than 20,000 natural compounds have been identified in the marine environment, with an increasing focus on marine metabolites as potential sources for developing effective therapeutic agents. The field of marine drug discovery has seen remarkable growth in recent years, with numerous marine-derived therapeutic candidates in various stages of clinical trials or awaiting approval. The ocean is a potential source of natural products with diverse pharmacological properties, including antimicrobial, anticancer, antiviral, antioxidative, and anti-inflammatory activities. However, commercializing marine natural products has been challenging due to low yields and specificity of specialized (secondary) metabolites. Marine specialized (secondary) metabolites and their diverse applications provides a broad overview of marine specialized metabolites and their potential in various industries. With comprehensive coverage, relevance to current trends, interdisciplinary approach, and practical applications, this book includes specific compounds or organisms, with a particular focus on addressing the challenges and limitations associated with them.
1. Cover image - p. c 2. Title page - p. i 3. Copyright - p. iv 4. Contents - p. v 5. Contributors - p. xiii 6. Preface - p. xvii 7. Part I Chemistry and biochemistry of marine specialized metabolites - p. 1 8. Chapter 1 Marine phenolic compounds and their halogenated derivatives: Structure, properties, isolation, characterization, and medical applications - p. 3 9. Chapter 2 Sterols: Chemistry and biochemistry of marine specialized metabolites - p. 39 10. Chapter 3 Chemistry and biochemistry of marine specialized secondary metabolites – peptides - p. 65 11. Part II Application of marine specialized metabolites - p. 87 12. Chapter 4 Marine secondary metabolites in oxidative stress are promising - p. 89 13. Chapter 5 Marine nutraceuticals: A solution for digestive tract health - p. 109 14. Chapter 6 Future prospects of marine resources in fighting oxidative stress, diabetes, and obesity - p. 135 15. Chapter 7 Promoting marine specialized bioactive metabolites against inflammation - p. 173 16. Chapter 8 Beneath the waves: Unveiling marine viral risks and human rewards - p. 205 17. Part III Marine organisms as a natural product resource and beyond - p. 221 18. Chapter 9 Marine secondary metabolites as a natural product resource - p. 223 19. Chapter 10 Marine-derived nutritional and bioactive compounds: Proteins and amino acids - p. 263 20. Chapter 11 Blue-bioeconomy; marine specialized metabolites at the forefront - p. 299 21. Chapter 12 Secondary metabolites of marine microorganisms: An underexplored area in metabolomics - p. 337 22. Chapter 13 Advances and prospects in the field of cosmeceuticals with marine resources - p. 377 23. Index - p. 407
Over the past 50 years, more than 20,000 natural compounds have been identified in the marine environment, with an increasing focus on marine metabolites as potential sources for developing effective therapeutic agents. The field of marine drug discovery has seen remarkable growth in recent years, with numerous marine-derived therapeutic candidates in various stages of clinical trials or awaiting approval. The ocean is a potential source of natural products with diverse pharmacological properties, including antimicrobial, anticancer, antiviral, antioxidative, and anti-inflammatory activities. However, commercializing marine natural products has been challenging due to low yields and specificity of specialized (secondary) metabolites. Marine specialized (secondary) metabolites and their diverse applications provides a broad overview of marine specialized metabolites and their potential in various industries. With comprehensive coverage, relevance to current trends, interdisciplinary approach, and practical applications, this book includes specific compounds or organisms, with a particular focus on addressing the challenges and limitations associated with them.
1. Cover image - p. c 2. Title page - p. i 3. Copyright - p. iv 4. Contents - p. v 5. Contributors - p. xiii 6. Preface - p. xvii 7. Part I Chemistry and biochemistry of marine specialized metabolites - p. 1 8. Chapter 1 Marine phenolic compounds and their halogenated derivatives: Structure, properties, isolation, characterization, and medical applications - p. 3 9. Chapter 2 Sterols: Chemistry and biochemistry of marine specialized metabolites - p. 39 10. Chapter 3 Chemistry and biochemistry of marine specialized secondary metabolites – peptides - p. 65 11. Part II Application of marine specialized metabolites - p. 87 12. Chapter 4 Marine secondary metabolites in oxidative stress are promising - p. 89 13. Chapter 5 Marine nutraceuticals: A solution for digestive tract health - p. 109 14. Chapter 6 Future prospects of marine resources in fighting oxidative stress, diabetes, and obesity - p. 135 15. Chapter 7 Promoting marine specialized bioactive metabolites against inflammation - p. 173 16. Chapter 8 Beneath the waves: Unveiling marine viral risks and human rewards - p. 205 17. Part III Marine organisms as a natural product resource and beyond - p. 221 18. Chapter 9 Marine secondary metabolites as a natural product resource - p. 223 19. Chapter 10 Marine-derived nutritional and bioactive compounds: Proteins and amino acids - p. 263 20. Chapter 11 Blue-bioeconomy; marine specialized metabolites at the forefront - p. 299 21. Chapter 12 Secondary metabolites of marine microorganisms: An underexplored area in metabolomics - p. 337 22. Chapter 13 Advances and prospects in the field of cosmeceuticals with marine resources - p. 377 23. Index - p. 407
