This issue of Immunology and Allergy Clinics, edited by Dr. Cem Akin, is devoted to Mastocytosis. Articles in this issue include Human Mast Cell Signal Transduction; Mast cell tryptase role in homeostasis and coagulation; Mastocytosis: Current Classification and Diagnostic criteria; Epidemiology, risk factors and prognosis of mastocytosis; Mast cell sarcoma: Clinical management; Molecular defects in mastocytosis: c-kit mutations and beyond; Flow cytometry in mastocytosis: Utility as a diagnostic and prognostic tool; Morphology of mastocytosis with special reference to immunophenotypical aberrancies; CD30 expression in mastocytosis; Extramedullary mastocytosis: Pathologic aspects; Bone involvement and osteoporosis in mastocytosis; Drug allergy in mastocytosis; Eosinophilia in mastocytosis; Venom allergy and mastocytosis; Skin disease in mastocytosis; Treatment of advanced mastocytosis; Treatment strategies of mediator related symptoms in mastocytosis; and Neuro and psychological involvement in Mastocytosis.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA - p. 7 6. Foreword - p. 8 7. Preface - p. 9 8. Erratum - p. 10 9. Diagnostic Criteria and Classification of Mastocytosis in 2014 - p. 11 10. Functional Deregulation of KIT - p. 18 11. Molecular Defects in Mastocytosis - p. 30 12. Mast Cell–Restricted Tetramer-Forming Tryptases and Their Beneficial Roles in Hemostasis and Blood Coagulation - p. 44 13. Epidemiology, Prognosis, and Risk Factors in Mastocytosis - p. 55 14. Flow Cytometry in Mastocytosis - p. 62 15. Mastocytosis - p. 70 16. Pathology of Extramedullary Mastocytosis - p. 74 17. CD30 in Systemic Mastocytosis - p. 83 18. Eosinophilia in Mast Cell Disease - p. 91 19. Epidemiology, Diagnosis, and Treatment of Hymenoptera Venom Allergy in Mastocytosis Patients - p. 95 20. Bone Involvement and Osteoporosis in Mastocytosis - p. 105 21. Drug Allergy in Mastocytosis - p. 112 22. Neuropsychological Features of Adult Mastocytosis - p. 117 23. Mast Cell Sarcoma - p. 127 24. Treatment Strategies in Mastocytosis - p. 132 25. Index - p. 141
This issue of Immunology and Allergy Clinics, edited by Dr. Cem Akin, is devoted to Mastocytosis. Articles in this issue include Human Mast Cell Signal Transduction; Mast cell tryptase role in homeostasis and coagulation; Mastocytosis: Current Classification and Diagnostic criteria; Epidemiology, risk factors and prognosis of mastocytosis; Mast cell sarcoma: Clinical management; Molecular defects in mastocytosis: c-kit mutations and beyond; Flow cytometry in mastocytosis: Utility as a diagnostic and prognostic tool; Morphology of mastocytosis with special reference to immunophenotypical aberrancies; CD30 expression in mastocytosis; Extramedullary mastocytosis: Pathologic aspects; Bone involvement and osteoporosis in mastocytosis; Drug allergy in mastocytosis; Eosinophilia in mastocytosis; Venom allergy and mastocytosis; Skin disease in mastocytosis; Treatment of advanced mastocytosis; Treatment strategies of mediator related symptoms in mastocytosis; and Neuro and psychological involvement in Mastocytosis.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA - p. 7 6. Foreword - p. 8 7. Preface - p. 9 8. Erratum - p. 10 9. Diagnostic Criteria and Classification of Mastocytosis in 2014 - p. 11 10. Functional Deregulation of KIT - p. 18 11. Molecular Defects in Mastocytosis - p. 30 12. Mast Cell–Restricted Tetramer-Forming Tryptases and Their Beneficial Roles in Hemostasis and Blood Coagulation - p. 44 13. Epidemiology, Prognosis, and Risk Factors in Mastocytosis - p. 55 14. Flow Cytometry in Mastocytosis - p. 62 15. Mastocytosis - p. 70 16. Pathology of Extramedullary Mastocytosis - p. 74 17. CD30 in Systemic Mastocytosis - p. 83 18. Eosinophilia in Mast Cell Disease - p. 91 19. Epidemiology, Diagnosis, and Treatment of Hymenoptera Venom Allergy in Mastocytosis Patients - p. 95 20. Bone Involvement and Osteoporosis in Mastocytosis - p. 105 21. Drug Allergy in Mastocytosis - p. 112 22. Neuropsychological Features of Adult Mastocytosis - p. 117 23. Mast Cell Sarcoma - p. 127 24. Treatment Strategies in Mastocytosis - p. 132 25. Index - p. 141
