Mechanisms of Cell Death and Opportunities for Therapeutic Development, volume four in the Perspectives in Translational Cell Biology series, offers content for professors, students and researchers across basic and translational biology. The book covers fundamental mechanisms, ranging from different forms of cell death and drug development, to efforts for treating disease, providing a valuable resource for readers interested in understanding cell death and relevant translational research. The book's editor, Diaqing Liao, has over twenty years’ experience teaching topics of cell death.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. List of contributors - p. ix 7. Chapter 1. Apoptosis, necroptosis, and pyroptosis in health and disease: an overview of molecular mechanisms, targets for therapeutic development, and known small molecule and biologic modulators - p. 1 8. Chapter 2. Cell death: machinery and regulation - p. 47 9. Chapter 3. Molecular mechanisms of cell death: a brief overview - p. 65 10. Chapter 4. Major methods and technologies for assessing cell death - p. 93 11. Chapter 5. Proteotoxicity and endoplasmic reticulum stress-mediated cell death - p. 119 12. Chapter 6. Protein phase separation in cell death and survival - p. 175 13. Chapter 7. Therapeutics targeting BCL2 family proteins - p. 197 14. Chapter 8. Ferroptosis: lipids, iron, cellular defense mechanisms and opportunities for drug development - p. 261 15. Index - p. 279
Mechanisms of Cell Death and Opportunities for Therapeutic Development, volume four in the Perspectives in Translational Cell Biology series, offers content for professors, students and researchers across basic and translational biology. The book covers fundamental mechanisms, ranging from different forms of cell death and drug development, to efforts for treating disease, providing a valuable resource for readers interested in understanding cell death and relevant translational research. The book's editor, Diaqing Liao, has over twenty years’ experience teaching topics of cell death.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. List of contributors - p. ix 7. Chapter 1. Apoptosis, necroptosis, and pyroptosis in health and disease: an overview of molecular mechanisms, targets for therapeutic development, and known small molecule and biologic modulators - p. 1 8. Chapter 2. Cell death: machinery and regulation - p. 47 9. Chapter 3. Molecular mechanisms of cell death: a brief overview - p. 65 10. Chapter 4. Major methods and technologies for assessing cell death - p. 93 11. Chapter 5. Proteotoxicity and endoplasmic reticulum stress-mediated cell death - p. 119 12. Chapter 6. Protein phase separation in cell death and survival - p. 175 13. Chapter 7. Therapeutics targeting BCL2 family proteins - p. 197 14. Chapter 8. Ferroptosis: lipids, iron, cellular defense mechanisms and opportunities for drug development - p. 261 15. Index - p. 279
