Comprehensive, clinically oriented, and practical, Medical Microbiology, Tenth Edition, remains the go-to text for foundational coverage of key interrelated concepts in medical microbiology, immunology, and infectious diseases. Clear and engaging coverage of the microbial world and its interface with our bodies and the environment provides the foundation to understand these roles in individual and public health and disease—helping you master the essentials of microbiology to effectively prepare you for coursework, exams, and your future career.
1. Section 1: Introduction - p. 1 2. 1. Introduction to Medical Microbiology - p. 2 3. 2. Human Microbiome in Health and Disease - p. 5 4. 3. Infection Prevention and Control - p. 11 5. Section 2: General Principles of Laboratory Diagnosis - p. 21 6. 4. Traditional Diagnostic Methods - p. 22 7. 5. Molecular and Proteomic Diagnostic Methods - p. 29 8. Section 3: Basic Concepts in the Immune Response - p. 35 9. 6. Elements of Host Protective Responses - p. 36 10. 7. Innate Host Responses - p. 46 11. 8. Antigen-Specific Immune Responses - p. 61 12. 9. Immune Responses to Infectious Agents - p. 81 13. 10. Antimicrobial Vaccines - p. 103 14. Section 4: Bacteriology - p. 111 15. 11. Bacterial Classification, Structure, and Replication - p. 112 16. 12. Bacterial Metabolism and Genetics - p. 124 17. 13. Mechanisms of Bacterial Pathogenesis - p. 134 18. 14. Role of Bacteria in Disease - p. 143 19. 15. Laboratory Diagnosis of Bacterial Diseases - p. 149 20. 16. Antibacterial Agents - p. 155 21. 17. Staphylococcus and Related Gram-Positive Cocci - p. 163 22. 18. Streptococcus and Enterococcus - p. 175.e2 23. 19. Bacillus - p. 194 24. 20. Listeria and Related Gram-Positive Bacteria - p. 200 25. 21. Mycobacterium and Related Acid-Fast Bacteria - p. 209 26. 22. Neisseria and Related Bacteria - p. 224 27. 23. Haemophilus and Related Bacteria - p. 233 28. 24. Enterobacterales - p. 240 29. 25. Vibrio and Related Bacteria - p. 254 30. 26. Pseudomonas and Related Bacteria - p. 261 31. 27. Campylobacter and Helicobacter - p. 269 32. 28. Miscellaneous Gram-Negative Rods - p. 276 33. 29. Clostridium and Clostridioides - p. 290 34. 30. Non–Spore-Forming Anaerobic Bacteria - p. 301 35. 31. Treponema, Borrelia, and Leptospira - p. 310 36. 32. Mycoplasma - p. 323 37. 33. Rickettsia, Ehrlichia, and Related Bacteria - p. 326 38. 34. Chlamydia - p. 336 39. Section 5: Virology - p. 343 40. 35. Viral Classification, Structure, and Replication - p. 344 41. 36. Mechanisms of Viral Pathogenesis - p. 361 42. 37. Role of Viruses in Disease - p. 372 43. 38. Laboratory Diagnosis of Viral Diseases - p. 378 44. 39. Antiviral Agents and Infection Control - p. 384 45. 40. Papillomaviruses and Polyomaviruses - p. 392 46. 41. Adenoviruses - p. 402 47. 42. Human Herpesviruses - p. 409 48. 43. Poxviruses - p. 432 49. 44. Parvoviruses - p. 438 50. 45. Picornaviruses - p. 443 51. 46. Coronaviruses - p. 455 52. 47. Noroviruses and Small RNA Enteric Viruses - p. 463 53. 48. Paramyxoviruses - p. 467 54. 49. Orthomyxoviruses - p. 479 55. 50. Rhabdoviruses, Filoviruses, and Bornaviruses - p. 489 56. 51. Reoviruses - p. 497 57. 52. Togaviruses, Flaviviruses, and Rubivirus (Matonaviridae) - p. 505 58. 53. Bunyavirales: Bunyaviridae and Arenaviridae - p. 517 59. 54. Retroviruses - p. 523 60. 55. Hepatitis Viruses - p. 540 61. 56. Prion Diseases - p. 557 62. Section 6: Mycology - p. 563 63. 57. Fungal Classification, Structure, and Replication - p. 564 64. 58. Pathogenesis of Fungal Disease - p. 570 65. 59. Role of Fungi in Disease - p. 579.e2 66. 60. Laboratory Diagnosis of Fungal Disease - p. 582 67. 61. Antifungal Agents - p. 592 68. 62. Superficial and Cutaneous Mycoses - p. 604 69. 63. Subcutaneous Mycoses - p. 614 70. 64. Systemic Mycoses Caused by Dimorphic Fungi - p. 624 71. 65. Opportunistic Mycoses - p. 641 72. 66. Fungal and Fungal-Like Infections of Unusual or Uncertain Etiology - p. 667 73. Section 7: Parasitology - p. 679 74. 67. Parasitic Classification, Structure, and Replication - p. 680 75. 68. Pathogenesis of Parasitic Diseases - p. 687 76. 69. Role of Parasites in Disease - p. 690.e2 77. 70. Laboratory Diagnosis of Parasitic Disease - p. 693 78. 71. Antiparasitic Agents - p. 702 79. 72. Intestinal and Urogenital Protozoa - p. 710 80. 73. Blood and Tissue Protozoa - p. 724 81. 74. Nematodes - p. 745 82. 75. Trematodes - p. 764 83. 76. Cestodes - p. 775 84. 77. Arthropods - p. 787 85. Section 8: Infectious Diseases by Organ System - p. 805 86. 78. Sepsis and Cardiovascular Infections - p. 806 87. 79. Ear, Nose and Throat Infections - p. 809 88. 80. Lower Respiratory Tract Infections - p. 812 89. 81. Eye, Brain and Nervous System Infections - p. 815 90. 82. Genitourinary Tract Infections - p. 820 91. 83. Gastrointestinal Infections - p. 823 92. 84. Musculoskeletal, Skin, and Soft Tissue Infections - p. 825 93. 85. Hematopoietic and Lymphatic System Infections - p. 830 94. Index - p. 835
Comprehensive, clinically oriented, and practical, Medical Microbiology, Tenth Edition, remains the go-to text for foundational coverage of key interrelated concepts in medical microbiology, immunology, and infectious diseases. Clear and engaging coverage of the microbial world and its interface with our bodies and the environment provides the foundation to understand these roles in individual and public health and disease—helping you master the essentials of microbiology to effectively prepare you for coursework, exams, and your future career.
1. Section 1: Introduction - p. 1 2. 1. Introduction to Medical Microbiology - p. 2 3. 2. Human Microbiome in Health and Disease - p. 5 4. 3. Infection Prevention and Control - p. 11 5. Section 2: General Principles of Laboratory Diagnosis - p. 21 6. 4. Traditional Diagnostic Methods - p. 22 7. 5. Molecular and Proteomic Diagnostic Methods - p. 29 8. Section 3: Basic Concepts in the Immune Response - p. 35 9. 6. Elements of Host Protective Responses - p. 36 10. 7. Innate Host Responses - p. 46 11. 8. Antigen-Specific Immune Responses - p. 61 12. 9. Immune Responses to Infectious Agents - p. 81 13. 10. Antimicrobial Vaccines - p. 103 14. Section 4: Bacteriology - p. 111 15. 11. Bacterial Classification, Structure, and Replication - p. 112 16. 12. Bacterial Metabolism and Genetics - p. 124 17. 13. Mechanisms of Bacterial Pathogenesis - p. 134 18. 14. Role of Bacteria in Disease - p. 143 19. 15. Laboratory Diagnosis of Bacterial Diseases - p. 149 20. 16. Antibacterial Agents - p. 155 21. 17. Staphylococcus and Related Gram-Positive Cocci - p. 163 22. 18. Streptococcus and Enterococcus - p. 175.e2 23. 19. Bacillus - p. 194 24. 20. Listeria and Related Gram-Positive Bacteria - p. 200 25. 21. Mycobacterium and Related Acid-Fast Bacteria - p. 209 26. 22. Neisseria and Related Bacteria - p. 224 27. 23. Haemophilus and Related Bacteria - p. 233 28. 24. Enterobacterales - p. 240 29. 25. Vibrio and Related Bacteria - p. 254 30. 26. Pseudomonas and Related Bacteria - p. 261 31. 27. Campylobacter and Helicobacter - p. 269 32. 28. Miscellaneous Gram-Negative Rods - p. 276 33. 29. Clostridium and Clostridioides - p. 290 34. 30. Non–Spore-Forming Anaerobic Bacteria - p. 301 35. 31. Treponema, Borrelia, and Leptospira - p. 310 36. 32. Mycoplasma - p. 323 37. 33. Rickettsia, Ehrlichia, and Related Bacteria - p. 326 38. 34. Chlamydia - p. 336 39. Section 5: Virology - p. 343 40. 35. Viral Classification, Structure, and Replication - p. 344 41. 36. Mechanisms of Viral Pathogenesis - p. 361 42. 37. Role of Viruses in Disease - p. 372 43. 38. Laboratory Diagnosis of Viral Diseases - p. 378 44. 39. Antiviral Agents and Infection Control - p. 384 45. 40. Papillomaviruses and Polyomaviruses - p. 392 46. 41. Adenoviruses - p. 402 47. 42. Human Herpesviruses - p. 409 48. 43. Poxviruses - p. 432 49. 44. Parvoviruses - p. 438 50. 45. Picornaviruses - p. 443 51. 46. Coronaviruses - p. 455 52. 47. Noroviruses and Small RNA Enteric Viruses - p. 463 53. 48. Paramyxoviruses - p. 467 54. 49. Orthomyxoviruses - p. 479 55. 50. Rhabdoviruses, Filoviruses, and Bornaviruses - p. 489 56. 51. Reoviruses - p. 497 57. 52. Togaviruses, Flaviviruses, and Rubivirus (Matonaviridae) - p. 505 58. 53. Bunyavirales: Bunyaviridae and Arenaviridae - p. 517 59. 54. Retroviruses - p. 523 60. 55. Hepatitis Viruses - p. 540 61. 56. Prion Diseases - p. 557 62. Section 6: Mycology - p. 563 63. 57. Fungal Classification, Structure, and Replication - p. 564 64. 58. Pathogenesis of Fungal Disease - p. 570 65. 59. Role of Fungi in Disease - p. 579.e2 66. 60. Laboratory Diagnosis of Fungal Disease - p. 582 67. 61. Antifungal Agents - p. 592 68. 62. Superficial and Cutaneous Mycoses - p. 604 69. 63. Subcutaneous Mycoses - p. 614 70. 64. Systemic Mycoses Caused by Dimorphic Fungi - p. 624 71. 65. Opportunistic Mycoses - p. 641 72. 66. Fungal and Fungal-Like Infections of Unusual or Uncertain Etiology - p. 667 73. Section 7: Parasitology - p. 679 74. 67. Parasitic Classification, Structure, and Replication - p. 680 75. 68. Pathogenesis of Parasitic Diseases - p. 687 76. 69. Role of Parasites in Disease - p. 690.e2 77. 70. Laboratory Diagnosis of Parasitic Disease - p. 693 78. 71. Antiparasitic Agents - p. 702 79. 72. Intestinal and Urogenital Protozoa - p. 710 80. 73. Blood and Tissue Protozoa - p. 724 81. 74. Nematodes - p. 745 82. 75. Trematodes - p. 764 83. 76. Cestodes - p. 775 84. 77. Arthropods - p. 787 85. Section 8: Infectious Diseases by Organ System - p. 805 86. 78. Sepsis and Cardiovascular Infections - p. 806 87. 79. Ear, Nose and Throat Infections - p. 809 88. 80. Lower Respiratory Tract Infections - p. 812 89. 81. Eye, Brain and Nervous System Infections - p. 815 90. 82. Genitourinary Tract Infections - p. 820 91. 83. Gastrointestinal Infections - p. 823 92. 84. Musculoskeletal, Skin, and Soft Tissue Infections - p. 825 93. 85. Hematopoietic and Lymphatic System Infections - p. 830 94. Index - p. 835