Medical Pharmacology & Therapeutics, now in its fifth edition, offers medical students all they need to know to become safe and effective prescribers. It forms a complete, integrated resource for basic pharmaceutical science, pathophysiology, clinical pharmacology, and therapeutics.
The fifth edition has been extensively revised and updated throughout. Key features include:
1. Cover image - p. cover 2. Title Page - p. iii 3. Table of Contents - p. v 4. Dedication - p. ii 5. Copyright - p. iv 6. Preface - p. vii 7. Drug dosage and nomenclature - p. ix 8. Section 1 General Principles - p. 1 9. 1 Principles of pharmacology and mechanisms of drug action - p. 3 10. 2 Pharmacokinetics - p. 33 11. 3 Drug discovery, safety and efficacy - p. 63 12. 4 Neurotransmission and the peripheral autonomic nervous system - p. 73 13. Section 2 The Cardiovascular System - p. 91 14. 5 Ischaemic heart disease - p. 93 15. 6 Systemic and pulmonary hypertension - p. 111 16. 7 Heart failure - p. 131 17. 8 Cardiac arrhythmias - p. 143 18. 9 Cerebrovascular disease and dementia - p. 161 19. 10 Peripheral vascular disease - p. 169 20. 11 Haemostasis - p. 175 21. Section 3 The Respiratory System - p. 191 22. 12 Asthma and chronic obstructive pulmonary disease - p. 193 23. 13 Respiratory disorders - p. 211 24. Section 4 The Renal System - p. 217 25. 14 Diuretics - p. 219 26. 15 Disorders of micturition - p. 231 27. 16 Erectile dysfunction - p. 239 28. Section 5 The Nervous System - p. 245 29. 17 General anaesthetics - p. 247 30. 18 Local anaesthetics - p. 257 31. 19 Opioid analgesics and the management of pain - p. 263 32. 20 Anxiety, obsessive-compulsive disorder and insomnia - p. 279 33. 21 Schizophrenia and bipolar disorder - p. 287 34. 22 Depression, attention deficit hyperactivity disorder and narcolepsy - p. 297 35. 23 Epilepsy - p. 311 36. 24 Extrapyramidal movement disorders and spasticity - p. 325 37. 25 Other neurological disorders - p. 337 38. 26 Migraine and other headaches - p. 341 39. Section 6 The Musculoskeletal System - p. 349 40. 27 The neuromuscular junction and neuromuscular blockade - p. 351 41. 28 Myasthenia gravis - p. 359 42. 29 Nonsteroidal antiinflammatory drugs - p. 363 43. 30 Rheumatoid arthritis, other inflammatory arthritides and osteoarthritis - p. 373 44. 31 Hyperuricaemia and gout - p. 385 45. Section 7 The Gastrointestinal System - p. 391 46. 32 Nausea and vomiting - p. 393 47. 33 Dyspepsia and peptic ulcer disease - p. 401 48. 34 Inflammatory bowel disease - p. 411 49. 35 Constipation, diarrhoea and irritable bowel syndrome - p. 417 50. 36 Liver disease - p. 425 51. 37 Obesity - p. 433 52. Section 8 The Immune System - p. 437 53. 38 The immune response and immunosuppressant drugs - p. 439 54. 39 Antihistamines and allergic disease - p. 451 55. Section 9 The Endocrine System and Metabolism - p. 457 56. 40 Diabetes mellitus - p. 459 57. 41 The thyroid and control of metabolic rate - p. 475 58. 42 Calcium metabolism and metabolic bone disease - p. 481 59. 43 Pituitary and hypothalamic hormones - p. 491 60. 44 Corticosteroids (glucocorticoids and mineralocorticoids) - p. 503 61. 45 Female reproduction - p. 513 62. 46 Androgens, antiandrogens and anabolic steroids - p. 531 63. 47 Anaemia and haematopoietic colony-stimulating factors - p. 537 64. 48 Lipid disorders - p. 547 65. Section 10 The Skin and Eyes - p. 559 66. 49 Skin disorders - p. 561 67. 50 The eye - p. 569 68. Section 11 Chemotherapy - p. 579 69. 51 Chemotherapy of infections - p. 581 70. Bacterial Infections - p. 581 71. Fungal Infections - p. 601 72. Viral Infections - p. 604 73. Protozoal Infections - p. 611 74. Helminthic Infections - p. 615 75. Self-Assessment - p. 617 76. Answers - p. 618 77. Further Reading - p. 620 78. 52 Chemotherapy of malignancy - p. 631 79. Section 12 General Features: Drug Toxicity and Prescribing - p. 657 80. 53 Drug toxicity and overdose - p. 659 81. 54 Substance abuse and dependence - p. 675 82. 55 Prescribing, adherence and information about medicines - p. 689 83. 56 Drug therapy in special situations - p. 695 84. Index - p. 707
Medical Pharmacology & Therapeutics, now in its fifth edition, offers medical students all they need to know to become safe and effective prescribers. It forms a complete, integrated resource for basic pharmaceutical science, pathophysiology, clinical pharmacology, and therapeutics.
The fifth edition has been extensively revised and updated throughout. Key features include:
1. Cover image - p. cover 2. Title Page - p. iii 3. Table of Contents - p. v 4. Dedication - p. ii 5. Copyright - p. iv 6. Preface - p. vii 7. Drug dosage and nomenclature - p. ix 8. Section 1 General Principles - p. 1 9. 1 Principles of pharmacology and mechanisms of drug action - p. 3 10. 2 Pharmacokinetics - p. 33 11. 3 Drug discovery, safety and efficacy - p. 63 12. 4 Neurotransmission and the peripheral autonomic nervous system - p. 73 13. Section 2 The Cardiovascular System - p. 91 14. 5 Ischaemic heart disease - p. 93 15. 6 Systemic and pulmonary hypertension - p. 111 16. 7 Heart failure - p. 131 17. 8 Cardiac arrhythmias - p. 143 18. 9 Cerebrovascular disease and dementia - p. 161 19. 10 Peripheral vascular disease - p. 169 20. 11 Haemostasis - p. 175 21. Section 3 The Respiratory System - p. 191 22. 12 Asthma and chronic obstructive pulmonary disease - p. 193 23. 13 Respiratory disorders - p. 211 24. Section 4 The Renal System - p. 217 25. 14 Diuretics - p. 219 26. 15 Disorders of micturition - p. 231 27. 16 Erectile dysfunction - p. 239 28. Section 5 The Nervous System - p. 245 29. 17 General anaesthetics - p. 247 30. 18 Local anaesthetics - p. 257 31. 19 Opioid analgesics and the management of pain - p. 263 32. 20 Anxiety, obsessive-compulsive disorder and insomnia - p. 279 33. 21 Schizophrenia and bipolar disorder - p. 287 34. 22 Depression, attention deficit hyperactivity disorder and narcolepsy - p. 297 35. 23 Epilepsy - p. 311 36. 24 Extrapyramidal movement disorders and spasticity - p. 325 37. 25 Other neurological disorders - p. 337 38. 26 Migraine and other headaches - p. 341 39. Section 6 The Musculoskeletal System - p. 349 40. 27 The neuromuscular junction and neuromuscular blockade - p. 351 41. 28 Myasthenia gravis - p. 359 42. 29 Nonsteroidal antiinflammatory drugs - p. 363 43. 30 Rheumatoid arthritis, other inflammatory arthritides and osteoarthritis - p. 373 44. 31 Hyperuricaemia and gout - p. 385 45. Section 7 The Gastrointestinal System - p. 391 46. 32 Nausea and vomiting - p. 393 47. 33 Dyspepsia and peptic ulcer disease - p. 401 48. 34 Inflammatory bowel disease - p. 411 49. 35 Constipation, diarrhoea and irritable bowel syndrome - p. 417 50. 36 Liver disease - p. 425 51. 37 Obesity - p. 433 52. Section 8 The Immune System - p. 437 53. 38 The immune response and immunosuppressant drugs - p. 439 54. 39 Antihistamines and allergic disease - p. 451 55. Section 9 The Endocrine System and Metabolism - p. 457 56. 40 Diabetes mellitus - p. 459 57. 41 The thyroid and control of metabolic rate - p. 475 58. 42 Calcium metabolism and metabolic bone disease - p. 481 59. 43 Pituitary and hypothalamic hormones - p. 491 60. 44 Corticosteroids (glucocorticoids and mineralocorticoids) - p. 503 61. 45 Female reproduction - p. 513 62. 46 Androgens, antiandrogens and anabolic steroids - p. 531 63. 47 Anaemia and haematopoietic colony-stimulating factors - p. 537 64. 48 Lipid disorders - p. 547 65. Section 10 The Skin and Eyes - p. 559 66. 49 Skin disorders - p. 561 67. 50 The eye - p. 569 68. Section 11 Chemotherapy - p. 579 69. 51 Chemotherapy of infections - p. 581 70. Bacterial Infections - p. 581 71. Fungal Infections - p. 601 72. Viral Infections - p. 604 73. Protozoal Infections - p. 611 74. Helminthic Infections - p. 615 75. Self-Assessment - p. 617 76. Answers - p. 618 77. Further Reading - p. 620 78. 52 Chemotherapy of malignancy - p. 631 79. Section 12 General Features: Drug Toxicity and Prescribing - p. 657 80. 53 Drug toxicity and overdose - p. 659 81. 54 Substance abuse and dependence - p. 675 82. 55 Prescribing, adherence and information about medicines - p. 689 83. 56 Drug therapy in special situations - p. 695 84. Index - p. 707
