Medicinal Chemistry, Volume 75, the latest release in the Advances in Inorganic Chemistry series, presents timely and informative summaries on current progress in a variety of subject areas. This acclaimed serial features reviews written by experts in the field, serving as an indispensable reference to advanced researchers that empowers readers to pursue new developments in each field. Users will find this to be a comprehensive overview of recent findings and trends from the last decade that covers various kinds of inorganic topics, from theoretical oriented supramolecular chemistry, to the quest for accurate calculations of spin states in transition metals.
1. Cover image - p. page_i 2. Title page - p. page_i 3. Table of Contents - p. page_i 4. Copyright - p. page_iv 5. Contributors - p. page_xi 6. Preface - p. page_xv 7. Feature Article - p. page_xvii 8. Chapter One: 150 years of the periodic table: New medicines and diagnostic agents - p. page_xvii 9. Chapter Two: Medicinal inorganic chemistry: New perspectives and targets for the periodic table - p. page_56 10. Chapter Three: Anti-cancer gold, platinum and iridium compounds with porphyrin and/or N-heterocyclic carbene ligand(s) - p. page_86 11. Chapter Four: Metal N-heterocyclic carbene complexes in medicinal chemistry - p. page_119 12. Chapter Five: Rational design of anticancer platinum(IV) prodrugs - p. page_148 13. Chapter Six: Bismuth drugs as antimicrobial agents - p. page_182 14. Chapter Seven: Antimony and bismuth as antimicrobial agents - p. page_205 15. Chapter Eight: Pharmacophore conjugation strategy for multi-targeting metal-based anticancer complexes - p. page_255 16. Chapter Nine: Organelle-targeting metal anticancer agents - p. page_285 17. Chapter Ten: From the hypothesis-driven development of organometallic anticancer drugs to new methods in mode of action studies - p. page_337 18. Chapter Eleven: Design and applications of catalytic metallodrugs containing the ATCUN motif - p. page_359 19. Chapter Twelve: The eyes have it: Using X-ray crystallography to determine the binding modes of medically relevant ruthenium/DNA complexes - p. page_391 20. Chapter Thirteen: Interaction of metal complexes with G-quadruplex DNA - p. page_424 21. Chapter Fourteen: CXCR4-targeted metal complexes for molecular imaging - p. page_445 22. Index - p. page_477
Medicinal Chemistry, Volume 75, the latest release in the Advances in Inorganic Chemistry series, presents timely and informative summaries on current progress in a variety of subject areas. This acclaimed serial features reviews written by experts in the field, serving as an indispensable reference to advanced researchers that empowers readers to pursue new developments in each field. Users will find this to be a comprehensive overview of recent findings and trends from the last decade that covers various kinds of inorganic topics, from theoretical oriented supramolecular chemistry, to the quest for accurate calculations of spin states in transition metals.
1. Cover image - p. page_i 2. Title page - p. page_i 3. Table of Contents - p. page_i 4. Copyright - p. page_iv 5. Contributors - p. page_xi 6. Preface - p. page_xv 7. Feature Article - p. page_xvii 8. Chapter One: 150 years of the periodic table: New medicines and diagnostic agents - p. page_xvii 9. Chapter Two: Medicinal inorganic chemistry: New perspectives and targets for the periodic table - p. page_56 10. Chapter Three: Anti-cancer gold, platinum and iridium compounds with porphyrin and/or N-heterocyclic carbene ligand(s) - p. page_86 11. Chapter Four: Metal N-heterocyclic carbene complexes in medicinal chemistry - p. page_119 12. Chapter Five: Rational design of anticancer platinum(IV) prodrugs - p. page_148 13. Chapter Six: Bismuth drugs as antimicrobial agents - p. page_182 14. Chapter Seven: Antimony and bismuth as antimicrobial agents - p. page_205 15. Chapter Eight: Pharmacophore conjugation strategy for multi-targeting metal-based anticancer complexes - p. page_255 16. Chapter Nine: Organelle-targeting metal anticancer agents - p. page_285 17. Chapter Ten: From the hypothesis-driven development of organometallic anticancer drugs to new methods in mode of action studies - p. page_337 18. Chapter Eleven: Design and applications of catalytic metallodrugs containing the ATCUN motif - p. page_359 19. Chapter Twelve: The eyes have it: Using X-ray crystallography to determine the binding modes of medically relevant ruthenium/DNA complexes - p. page_391 20. Chapter Thirteen: Interaction of metal complexes with G-quadruplex DNA - p. page_424 21. Chapter Fourteen: CXCR4-targeted metal complexes for molecular imaging - p. page_445 22. Index - p. page_477
