Membrane Transporters in the Pathogenesis of Cardiovascular and Lung Disorders, Volume 83, the latest release in the Current Topics in Membranes series, highlights new advances in the field, with this volume presenting chapters from recognized experts on topics such as cardiotonic steroids, Na+, K+ pumps and vascular fibrosis, purinergic signaling in the lung, structural models of a2-subunit N-termini and binding interfaces, ubiquitous and cell type-specific transcriptomic changes triggered by dissipation of monovalent cation gradients, the Na, K-ATPase alpha2 isoform in cardiovascular pathologies, the role of cell swelling and volume-sensitive ion channels in stroke pathology, structure-function relationships in the renal NaCl cotransporter, and more.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xi 6. Preface - p. xv 7. Chapter One: Acute salt loading and cardiotonic steroids in resistant hypertension - p. xvii 8. Chapter Two: Control of lung myofibroblast transformation by monovalent ion transporters - p. 13 9. Chapter Three: Mechanosensitive ATP release in the lungs: New insights from real-time luminescence imaging studies - p. 43 10. Chapter Four: Structural model of a2-subunit N-terminus and its binding interface for Arf-GEF CTH2: Implication for regulation of V-ATPase, CTH2 function and rational drug design - p. 76 11. Chapter Five: Ubiquitous and cell type-specific transcriptomic changes triggered by dissipation of monovalent cation gradients in rodent cells: Physiological and pathophysiological implications - p. 106 12. Chapter Six: The Na,K-ATPase in vascular smooth muscle cells - p. 148 13. Chapter Seven: Structure-function relationships in the renal NaCl cotransporter (NCC) - p. 175 14. Chapter Eight: Roles of volume-regulatory anion channels, VSOR and Maxi-Cl, in apoptosis, cisplatin resistance, necrosis, ischemic cell death, stroke and myocardial infarction - p. 204 15. Chapter Nine: Molecular mechanisms for the regulation of blood pressure by potassium - p. 283 16. Chapter Ten: Hormonal regulation of Na+-K+-ATPase from the evolutionary perspective - p. 313 17. Chapter Eleven: Ion channels and transporters in diabetic kidney disease - p. 351
Membrane Transporters in the Pathogenesis of Cardiovascular and Lung Disorders, Volume 83, the latest release in the Current Topics in Membranes series, highlights new advances in the field, with this volume presenting chapters from recognized experts on topics such as cardiotonic steroids, Na+, K+ pumps and vascular fibrosis, purinergic signaling in the lung, structural models of a2-subunit N-termini and binding interfaces, ubiquitous and cell type-specific transcriptomic changes triggered by dissipation of monovalent cation gradients, the Na, K-ATPase alpha2 isoform in cardiovascular pathologies, the role of cell swelling and volume-sensitive ion channels in stroke pathology, structure-function relationships in the renal NaCl cotransporter, and more.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xi 6. Preface - p. xv 7. Chapter One: Acute salt loading and cardiotonic steroids in resistant hypertension - p. xvii 8. Chapter Two: Control of lung myofibroblast transformation by monovalent ion transporters - p. 13 9. Chapter Three: Mechanosensitive ATP release in the lungs: New insights from real-time luminescence imaging studies - p. 43 10. Chapter Four: Structural model of a2-subunit N-terminus and its binding interface for Arf-GEF CTH2: Implication for regulation of V-ATPase, CTH2 function and rational drug design - p. 76 11. Chapter Five: Ubiquitous and cell type-specific transcriptomic changes triggered by dissipation of monovalent cation gradients in rodent cells: Physiological and pathophysiological implications - p. 106 12. Chapter Six: The Na,K-ATPase in vascular smooth muscle cells - p. 148 13. Chapter Seven: Structure-function relationships in the renal NaCl cotransporter (NCC) - p. 175 14. Chapter Eight: Roles of volume-regulatory anion channels, VSOR and Maxi-Cl, in apoptosis, cisplatin resistance, necrosis, ischemic cell death, stroke and myocardial infarction - p. 204 15. Chapter Nine: Molecular mechanisms for the regulation of blood pressure by potassium - p. 283 16. Chapter Ten: Hormonal regulation of Na+-K+-ATPase from the evolutionary perspective - p. 313 17. Chapter Eleven: Ion channels and transporters in diabetic kidney disease - p. 351
