Metabolites as Signals in Immunity and Inflammation describes the revolution in the definition of the word metabolism, highlighting changes in thinking about the whole field of immunology. These changes occur thanks to breakthrough experiments in basic research, and with the help of new technologies that allow for the testing of immunology hypotheses. In recent years, a substantial number of findings have been made around immunometabolism. What is emerging is a complex interplay between metabolic reprogramming and immunity, which is providing an extra dimension to our understanding of the immune system in health and disease.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xi 7. Chapter 1. The metabolism revolution: you need energy to fight and to live - p. 1 8. Chapter 2. Host–microbe interactions in the lung and the role of immunometabolism - p. 7 9. Chapter 3. Crosstalk between metabolites and myeloid cell biology - p. 27 10. Chapter 4. Immunometabolism in macrophage cell death - p. 63 11. Chapter 5. Computational modeling of metabolism in oncology - p. 81 12. Chapter 6. Immunometabolic contributions to the pathogenesis of cardiovascular disease - p. 109 13. Chapter 7. Damage-associated molecular patterns as metabolic regulators of innate immunity - p. 129 14. Chapter 8. Adaptive immunity and metabolism - p. 157 15. Chapter 9. Regulation of cytokine secretion by immunometabolites - p. 191 16. Chapter 10. Omics metabolism tools in antiaging drug discovery - p. 209 17. Chapter 11. Neuroimmunometabolism as a regulator of obesity - p. 227 18. Chapter 12. Clinical stage drugs utilizing cellular metabolism pathways - p. 263 19. Index - p. 275
Metabolites as Signals in Immunity and Inflammation describes the revolution in the definition of the word metabolism, highlighting changes in thinking about the whole field of immunology. These changes occur thanks to breakthrough experiments in basic research, and with the help of new technologies that allow for the testing of immunology hypotheses. In recent years, a substantial number of findings have been made around immunometabolism. What is emerging is a complex interplay between metabolic reprogramming and immunity, which is providing an extra dimension to our understanding of the immune system in health and disease.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xi 7. Chapter 1. The metabolism revolution: you need energy to fight and to live - p. 1 8. Chapter 2. Host–microbe interactions in the lung and the role of immunometabolism - p. 7 9. Chapter 3. Crosstalk between metabolites and myeloid cell biology - p. 27 10. Chapter 4. Immunometabolism in macrophage cell death - p. 63 11. Chapter 5. Computational modeling of metabolism in oncology - p. 81 12. Chapter 6. Immunometabolic contributions to the pathogenesis of cardiovascular disease - p. 109 13. Chapter 7. Damage-associated molecular patterns as metabolic regulators of innate immunity - p. 129 14. Chapter 8. Adaptive immunity and metabolism - p. 157 15. Chapter 9. Regulation of cytokine secretion by immunometabolites - p. 191 16. Chapter 10. Omics metabolism tools in antiaging drug discovery - p. 209 17. Chapter 11. Neuroimmunometabolism as a regulator of obesity - p. 227 18. Chapter 12. Clinical stage drugs utilizing cellular metabolism pathways - p. 263 19. Index - p. 275
