This issue reviews the role of metals in neurodegenerative diseases; including Parkinson’s and Huntington’s disease; restless leg syndrome and NBIA disorders; and Wilson’s disease and manganese and calcium accumulation disorders. An update on advances in neuroimaging and pathology of metal related disease is also presented.
This volume of International Review of Neurobiology brings together cutting-edge research on metal related neurodegenerative disease. It reviews the role of metals in neurodegenerative diseases, including Parkinson’s and Huntington’s disease; restless leg syndrome and NBIA disorders; and Wilson’s disease and manganese and calcium accumulation disorders. An update on advances in neuroimaging and pathology of metal related disease is also presented.
1. Cover image 2. Title page 3. Table of Contents 4. Series Page 5. Copyright 6. Contributors 7. Preface 8. Chapter One. The Relevance of Metals in the Pathophysiology of Neurodegeneration, Pathological Considerations 9. Chapter Two. Pantothenate Kinase-Associated Neurodegeneration (PKAN) and PLA2G6-Associated Neurodegeneration (PLAN): Review of Two Major Neurodegeneration with Brain Iron Accumulation (NBIA) Phenotypes 10. Chapter Three. Mitochondrial Membrane Protein-Associated Neurodegeneration (MPAN) 11. Chapter Four. BPAN: The Only X-Linked Dominant NBIA Disorder 12. Chapter Five. Neuroferritinopathy 13. Chapter Six. Aceruloplasminemia: An Update 14. Chapter Seven. Therapeutic Advances in Neurodegeneration with Brain Iron Accumulation 15. Chapter Eight. The Neuropathology of Neurodegeneration with Brain Iron Accumulation 16. Chapter Nine. Imaging of Iron 17. Chapter Ten. The Role of Iron Imaging in Huntington’s Disease 18. Chapter Eleven. Lysosomal Storage Disorders and Iron 19. Chapter Twelve. Manganese and the Brain 20. Chapter Thirteen. Update on Wilson Disease 21. Chapter Fourteen. An Update on Primary Familial Brain Calcification 22. Index 23. Contents of Recent Volumes
This issue reviews the role of metals in neurodegenerative diseases; including Parkinson’s and Huntington’s disease; restless leg syndrome and NBIA disorders; and Wilson’s disease and manganese and calcium accumulation disorders. An update on advances in neuroimaging and pathology of metal related disease is also presented.
This volume of International Review of Neurobiology brings together cutting-edge research on metal related neurodegenerative disease. It reviews the role of metals in neurodegenerative diseases, including Parkinson’s and Huntington’s disease; restless leg syndrome and NBIA disorders; and Wilson’s disease and manganese and calcium accumulation disorders. An update on advances in neuroimaging and pathology of metal related disease is also presented.
1. Cover image 2. Title page 3. Table of Contents 4. Series Page 5. Copyright 6. Contributors 7. Preface 8. Chapter One. The Relevance of Metals in the Pathophysiology of Neurodegeneration, Pathological Considerations 9. Chapter Two. Pantothenate Kinase-Associated Neurodegeneration (PKAN) and PLA2G6-Associated Neurodegeneration (PLAN): Review of Two Major Neurodegeneration with Brain Iron Accumulation (NBIA) Phenotypes 10. Chapter Three. Mitochondrial Membrane Protein-Associated Neurodegeneration (MPAN) 11. Chapter Four. BPAN: The Only X-Linked Dominant NBIA Disorder 12. Chapter Five. Neuroferritinopathy 13. Chapter Six. Aceruloplasminemia: An Update 14. Chapter Seven. Therapeutic Advances in Neurodegeneration with Brain Iron Accumulation 15. Chapter Eight. The Neuropathology of Neurodegeneration with Brain Iron Accumulation 16. Chapter Nine. Imaging of Iron 17. Chapter Ten. The Role of Iron Imaging in Huntington’s Disease 18. Chapter Eleven. Lysosomal Storage Disorders and Iron 19. Chapter Twelve. Manganese and the Brain 20. Chapter Thirteen. Update on Wilson Disease 21. Chapter Fourteen. An Update on Primary Familial Brain Calcification 22. Index 23. Contents of Recent Volumes
