Microbial Forensics is a rapidly evolving scientific discipline. In the last decade, and particularly due to the anthrax letter attacks in the United States, microbial forensics has become more formalized and has played an increasingly greater role in crime investigations. This has brought renewed interest, development and application of new technologies, and new rules of forensic and policy engagement. It has many applications ranging from biodefense, criminal investigations, providing intelligence information, making society more secure, and helping protect precious resources, particularly human life. A combination of diverse areas is investigated, including the major disciplines of biology, microbiology, medicine, chemistry, physics, statistics, population genetics, and computer science.
Microbial Forensics, Second Edition is fully revised and updated and serves as a complete reference of the discipline. It describes the advances, as well as the challenges and opportunities ahead, and will be integral in applying science to help solve future biocrimes.
1. Introduction: The Rapidly Evolving Discipline of Microbial Forensics 2. Chapter 1: The Kameido Anthrax Incident: A Microbial Forensics Case Study 3. Chapter 2: Microbial Forensic Investigation of the Anthrax-Letter Attacks 4. Chapter 3: Food-Borne Outbreaks: What’s New, What’s Not, and Where Do We Go from Here? 5. Chapter 4: Genotype and Geography: The Global Distribution of Bovine Tuberculosis 6. Chapter 5: Tracing Meat Products through the Production and Distribution Chain from Farm to Consumer 7. Chapter 6: Microbial Forensics of RNA Viruses: Foot-and-Mouth Disease Virus 8. Chapter 7: Forensic Plant Pathology 9. Chapter 8: Influenza Forensics 10. Chapter 9: Keeping Track of Viruses 11. Chapter 10: Microbial Forensic Analysis of Trace and Unculturable Specimens 12. Chapter 11: Molecular Microbial Surveillance and Discovery in Bioforensics 13. Chapter 12: Assessment of the Threat 14. Chapter 13: Select Agent Regulations 15. Chapter 14: Biosurety in the Post-9/11 Era 16. Chapter 15: Forensic Public Health: Epidemiological and Microbiological Investigations for Biosecurity 17. Chapter 16: Forensic Analysis in Bacterial Pathogens 18. Chapter 17: Rickettsia and Coxiella 19. Chapter 18: Forensics and Epidemiology of Fungal Pathogens 20. Chapter 19: Ricin Forensics: Comparisons to Microbial Forensics 21. Chapter 20: Forensic Aspects of Biological Toxins 22. Chapter 21: Use of Host Factors in Microbial Forensics 23. Chapter 22: Collection and Preservation of Microbial Forensic Samples 24. Chapter 23: Sampling for Microbial Forensic Investigations 25. Chapter 24: Toxin Analysis Using Mass Spectrometry 26. Chapter 25: Electron Beam-Based Methods for Bioforensic Investigations 27. Chapter 26: Proteomics Development and Application for Bioforensics 28. Chapter 27: High-Throughput Sequencing 29. Chapter 28: Genomics 30. Chapter 29: Design of Genomic Signatures for Pathogen Identification and Characterization 31. Chapter 30: Nonbiological Measurements on Biological Agents 32. Chapter 31: Inferential Validation and Evidence Interpretation 33. Chapter 32: Microbial Forensic Investigations in the Context of Bacterial Population Genetics 34. Chapter 33: Population Genetic Considerations in Statistical Interpretation of Microbial Forensic Data in Comparison with Human DNA Forensic Standard 35. Chapter 34: Biorepositories and Their Foundations—Microbial Forensic Considerations 36. Chapter 35: A U.S. Research Strategy for Microbial Forensics: From Genesis to Implementation 37. Chapter 36: The National Bioforensic Analysis Center 38. Chapter 37: Microbial Forensics in Australia—The Australian Federal Police Perspective 39. Chapter 38: Validation of Microbial Forensics in Scientific, Legal, and Policy Contexts 40. Chapter 39: Microbial Forensics: Educating the Workforce and the Community 41. Chapter 40: So You Really Want to Be an Expert Witness? A Primer for the Occasional Expert Witness 42. Chapter 41: Microbial Forensics, What Next? 43. Index
Microbial Forensics is a rapidly evolving scientific discipline. In the last decade, and particularly due to the anthrax letter attacks in the United States, microbial forensics has become more formalized and has played an increasingly greater role in crime investigations. This has brought renewed interest, development and application of new technologies, and new rules of forensic and policy engagement. It has many applications ranging from biodefense, criminal investigations, providing intelligence information, making society more secure, and helping protect precious resources, particularly human life. A combination of diverse areas is investigated, including the major disciplines of biology, microbiology, medicine, chemistry, physics, statistics, population genetics, and computer science.
Microbial Forensics, Second Edition is fully revised and updated and serves as a complete reference of the discipline. It describes the advances, as well as the challenges and opportunities ahead, and will be integral in applying science to help solve future biocrimes.
1. Introduction: The Rapidly Evolving Discipline of Microbial Forensics 2. Chapter 1: The Kameido Anthrax Incident: A Microbial Forensics Case Study 3. Chapter 2: Microbial Forensic Investigation of the Anthrax-Letter Attacks 4. Chapter 3: Food-Borne Outbreaks: What’s New, What’s Not, and Where Do We Go from Here? 5. Chapter 4: Genotype and Geography: The Global Distribution of Bovine Tuberculosis 6. Chapter 5: Tracing Meat Products through the Production and Distribution Chain from Farm to Consumer 7. Chapter 6: Microbial Forensics of RNA Viruses: Foot-and-Mouth Disease Virus 8. Chapter 7: Forensic Plant Pathology 9. Chapter 8: Influenza Forensics 10. Chapter 9: Keeping Track of Viruses 11. Chapter 10: Microbial Forensic Analysis of Trace and Unculturable Specimens 12. Chapter 11: Molecular Microbial Surveillance and Discovery in Bioforensics 13. Chapter 12: Assessment of the Threat 14. Chapter 13: Select Agent Regulations 15. Chapter 14: Biosurety in the Post-9/11 Era 16. Chapter 15: Forensic Public Health: Epidemiological and Microbiological Investigations for Biosecurity 17. Chapter 16: Forensic Analysis in Bacterial Pathogens 18. Chapter 17: Rickettsia and Coxiella 19. Chapter 18: Forensics and Epidemiology of Fungal Pathogens 20. Chapter 19: Ricin Forensics: Comparisons to Microbial Forensics 21. Chapter 20: Forensic Aspects of Biological Toxins 22. Chapter 21: Use of Host Factors in Microbial Forensics 23. Chapter 22: Collection and Preservation of Microbial Forensic Samples 24. Chapter 23: Sampling for Microbial Forensic Investigations 25. Chapter 24: Toxin Analysis Using Mass Spectrometry 26. Chapter 25: Electron Beam-Based Methods for Bioforensic Investigations 27. Chapter 26: Proteomics Development and Application for Bioforensics 28. Chapter 27: High-Throughput Sequencing 29. Chapter 28: Genomics 30. Chapter 29: Design of Genomic Signatures for Pathogen Identification and Characterization 31. Chapter 30: Nonbiological Measurements on Biological Agents 32. Chapter 31: Inferential Validation and Evidence Interpretation 33. Chapter 32: Microbial Forensic Investigations in the Context of Bacterial Population Genetics 34. Chapter 33: Population Genetic Considerations in Statistical Interpretation of Microbial Forensic Data in Comparison with Human DNA Forensic Standard 35. Chapter 34: Biorepositories and Their Foundations—Microbial Forensic Considerations 36. Chapter 35: A U.S. Research Strategy for Microbial Forensics: From Genesis to Implementation 37. Chapter 36: The National Bioforensic Analysis Center 38. Chapter 37: Microbial Forensics in Australia—The Australian Federal Police Perspective 39. Chapter 38: Validation of Microbial Forensics in Scientific, Legal, and Policy Contexts 40. Chapter 39: Microbial Forensics: Educating the Workforce and the Community 41. Chapter 40: So You Really Want to Be an Expert Witness? A Primer for the Occasional Expert Witness 42. Chapter 41: Microbial Forensics, What Next? 43. Index
