As the field of genomics has progressed, our understanding of microbiology has also developed. With the advent of next-generation sequencing methods and advancements in instrumental resolution, complex transcriptome, proteome, and metabolome data could be analyzed, as well as detailed annotation of microbial genomes. Microbial Genomics: Clinical, Pharmaceutical and Industrial Applications focuses on the various applications of microbial genomics in clinical, pharmaceutical and industrial fields. It consists of four parts devoted to bacterial, viral, and fungal genomics, as well as their applications in clinical, pharmaceutical, and industrial fields. Chapters are written by experts in their respective disciplines and are tightly organized with an introduction to detailed descriptions, available software implementation, applications, advanced topics, summaries, analytic questions, exercises, and suggested readings.
Throughout this book, the latest genomics and biotechnological developments and discoveries as well as open problems and future challenges on microbial genomics will be highlighted. Readers will be introduced to state-of-the-art developments and trends of microbial genomics, its clinical, pharmaceutical, and industrial applications. The book will be beneficial for researchers who study microbial genomics in universities, post-graduate and graduate programs (biology, biotechnology, medicine, genetics, microbiology, industrial and environmental microbiology, etc.), as well as the pharmaceutical and industrial sector.
1. Chapter 1 Introduction to microbial genomics - p. 1 2. Chapter 2 Viral genomics - p. 31 3. Chapter 3 Fungal genomics - p. 71 4. Chapter 4 Introduction to genomic-based clinical applications - p. 97 5. Chapter 5 Molecular techniques for the diagnosis of viral infections - p. 117 6. Chapter 6 Bacterial identification and diagnosis of bacterial infections through genomics, proteomics, nanotechnology, machine learning, and microelectromechanical systems - p. 143 7. Chapter 7 Fungal identification and diagnosis - p. 173 8. Chapter 8 Introduction to genomics-based pharmaceutical applications - p. 205 9. Chapter 9 Antiviral history and viral targets for antiviral therapy - p. 219 10. Chapter 10 Host- and genomics-based antiviral approaches - p. 277 11. Chapter 11 Antibiotic resistance and target-based technologies for drug development - p. 311 12. Chapter 12 Discovery and development of new antibacterial drugs - p. 333 13. Chapter 13 Potential targets for the development of antifungal drugs - p. 361 14. Chapter 14 Introduction to genomics-based industrial applications - p. 385 15. Chapter 15 Tailed phage machinery - p. 395 16. Chapter 16 Advances in fungal biotechnology in agriculture - p. 427 17. Index - p. 465
As the field of genomics has progressed, our understanding of microbiology has also developed. With the advent of next-generation sequencing methods and advancements in instrumental resolution, complex transcriptome, proteome, and metabolome data could be analyzed, as well as detailed annotation of microbial genomes. Microbial Genomics: Clinical, Pharmaceutical and Industrial Applications focuses on the various applications of microbial genomics in clinical, pharmaceutical and industrial fields. It consists of four parts devoted to bacterial, viral, and fungal genomics, as well as their applications in clinical, pharmaceutical, and industrial fields. Chapters are written by experts in their respective disciplines and are tightly organized with an introduction to detailed descriptions, available software implementation, applications, advanced topics, summaries, analytic questions, exercises, and suggested readings.
Throughout this book, the latest genomics and biotechnological developments and discoveries as well as open problems and future challenges on microbial genomics will be highlighted. Readers will be introduced to state-of-the-art developments and trends of microbial genomics, its clinical, pharmaceutical, and industrial applications. The book will be beneficial for researchers who study microbial genomics in universities, post-graduate and graduate programs (biology, biotechnology, medicine, genetics, microbiology, industrial and environmental microbiology, etc.), as well as the pharmaceutical and industrial sector.
1. Chapter 1 Introduction to microbial genomics - p. 1 2. Chapter 2 Viral genomics - p. 31 3. Chapter 3 Fungal genomics - p. 71 4. Chapter 4 Introduction to genomic-based clinical applications - p. 97 5. Chapter 5 Molecular techniques for the diagnosis of viral infections - p. 117 6. Chapter 6 Bacterial identification and diagnosis of bacterial infections through genomics, proteomics, nanotechnology, machine learning, and microelectromechanical systems - p. 143 7. Chapter 7 Fungal identification and diagnosis - p. 173 8. Chapter 8 Introduction to genomics-based pharmaceutical applications - p. 205 9. Chapter 9 Antiviral history and viral targets for antiviral therapy - p. 219 10. Chapter 10 Host- and genomics-based antiviral approaches - p. 277 11. Chapter 11 Antibiotic resistance and target-based technologies for drug development - p. 311 12. Chapter 12 Discovery and development of new antibacterial drugs - p. 333 13. Chapter 13 Potential targets for the development of antifungal drugs - p. 361 14. Chapter 14 Introduction to genomics-based industrial applications - p. 385 15. Chapter 15 Tailed phage machinery - p. 395 16. Chapter 16 Advances in fungal biotechnology in agriculture - p. 427 17. Index - p. 465
