As both a practical reference for clinicians and researchers and an effective self-assessment tool for board preparation, Middleton's Allergy: Principles and Practice remains the #1 authoritative resource in the field. This fully revised 10th Edition brings you up to date with recent advancements in basic science and clinical applications regarding allergy practice and disease mechanisms, offering unparalleled guidance on the full spectrum of allergy across the lifespan.
1. Introduction - p. 1141 2. Normal Immunoglobulin E Production - p. 1142 3. Immunoglobulin E in Allergic Disease - p. 1143 4. Immunoglobulin E in Infectious and Parasitic Disease - p. 1146 5. Immunoglobulin E in Nonatopic Diseases - p. 1147 6. Environmental Exposures and Immunoglobulin E - p. 1148 7. Summary - p. 1149 8. References - p. 1149 9. 66 In Vivo Methods for the Study and Diagnosis of IgE-Mediated Allergy - p. 1152 10. CONTENTS - p. 1152 11. Introduction - p. 1152 12. Pathophysiology of the Skin Response - p. 1152 13. Techniques of Skin Tests - p. 1153 14. Factors That Affect Skin Tests - p. 1157 15. Interpretation of Skin Tests - p. 1159 16. Skin Tests Used for Nondiagnostic Purposes - p. 1161 17. Availability of Extracts for In Vivo Diagnosis - p. 1162 18. Conclusion - p. 1162 19. References - p. 1162 20. 67 Approach to the Patient With Recurrent Infections - p. 1166 21. 68 Primary Immunodeficiency Diseases - p. 1178 22. 69 Treatment of Primary Immunodeficiency Diseases - p. 1208 23. 70 HIV Infection and Allergic Disease - p. 1225 24. 71 Laboratory Tests for Allergic and Immunodeficiency Diseases - p. 1238 25. 72 Eosinophilia and Eosinophil-Related Disorders - p. 1255 26. 73 Mastocytosis - p. 1275 27. 74 Anaphylaxis - p. 1287 28. 75 Insect Allergy - p. 1308 29. 76 Drug Allergy - p. 1325 30. 77 Hypersensitivity to Aspirin and Other Nonsteroidal Antiinflammatory Drugs - p. 1350 31. 78 Reactions to Foods - p. 1361 32. 79 Oral Food Challenge Testing - p. 1395 33. 80 Food Allergy Management, Prevention, and Therapy - p. 1403 34. 81 Adverse Reactions to Vaccines - p. 1430 35. Section H Therapeutics - p. p1453 36. 82 Allergen Immunotherapy for Inhalant Allergens - p. 1453 37. 83 Principles of Pharmacotherapeutics - p. 1486 38. 84 Precision Medicine in Allergic Disorders - p. 1498 39. 85 Optimizing Adherence in Practice - p. 1511 40. 86 Anti-Immunoglobulin E Therapy - p. 1520 41. 87 Cytokine-Specific Therapy in Asthma - p. 1535 42. 88 Histamine and Antihistamines* - p. 1551 43. Contents - p. 1551 44. Introduction - p. 1551 45. Molecular Basis of Histamine Action - p. 1551 46. Histamine Receptors - p. 1553 47. Histamine in Immune Response Regulation - p. 1555 48. Clinical Pharmacology of H1 Antihistamines - p. 1559 49. Allergic Rhinitis - p. 1563 50. Allergic Conjunctivitis - p. 1566 51. Urticaria - p. 1568 52. Other Diseases and Uses - p. 1569 53. Adverse Effects - p. 1571 54. Summary and Future Directions - p. 1576 55. Acknowledgment - p. 1577 56. References - p. 1577 57. 89 Inhaled β2-Agonists - p. 1583 58. Contents - p. 1583 59. Introduction - p. 1583 60. Historical Background - p. 1583 61. Pharmacology of β2-Agonists - p. 1583 62. β2-Receptor Structure and Activation - p. 1584 63. Efficacy of Inhaled β2-Agonists - p. 1585 64. ICS/formoterol Combinations Used as Single-Inhaler Maintenance and Reliever Therapy - p. 1588 65. Conclusion - p. 1588 66. References - p. 1589 67. 90 Anticholinergic Therapies - p. 1591 68. 91 Glucocorticoids - p. 1605 69. 92 Antileukotriene Therapy in Asthma - p. 1630 70. 93 Unconventional Theories and Unproven Methods in Allergy - p. 1646 71. 94 Complementary and Integrative Health - p. 1659 72. CD Molecules - p. 1687 73. Index - p. I1 74. Answers to Self-Assessment Questions - p. page_e1
As both a practical reference for clinicians and researchers and an effective self-assessment tool for board preparation, Middleton's Allergy: Principles and Practice remains the #1 authoritative resource in the field. This fully revised 10th Edition brings you up to date with recent advancements in basic science and clinical applications regarding allergy practice and disease mechanisms, offering unparalleled guidance on the full spectrum of allergy across the lifespan.
1. Introduction - p. 1141 2. Normal Immunoglobulin E Production - p. 1142 3. Immunoglobulin E in Allergic Disease - p. 1143 4. Immunoglobulin E in Infectious and Parasitic Disease - p. 1146 5. Immunoglobulin E in Nonatopic Diseases - p. 1147 6. Environmental Exposures and Immunoglobulin E - p. 1148 7. Summary - p. 1149 8. References - p. 1149 9. 66 In Vivo Methods for the Study and Diagnosis of IgE-Mediated Allergy - p. 1152 10. CONTENTS - p. 1152 11. Introduction - p. 1152 12. Pathophysiology of the Skin Response - p. 1152 13. Techniques of Skin Tests - p. 1153 14. Factors That Affect Skin Tests - p. 1157 15. Interpretation of Skin Tests - p. 1159 16. Skin Tests Used for Nondiagnostic Purposes - p. 1161 17. Availability of Extracts for In Vivo Diagnosis - p. 1162 18. Conclusion - p. 1162 19. References - p. 1162 20. 67 Approach to the Patient With Recurrent Infections - p. 1166 21. 68 Primary Immunodeficiency Diseases - p. 1178 22. 69 Treatment of Primary Immunodeficiency Diseases - p. 1208 23. 70 HIV Infection and Allergic Disease - p. 1225 24. 71 Laboratory Tests for Allergic and Immunodeficiency Diseases - p. 1238 25. 72 Eosinophilia and Eosinophil-Related Disorders - p. 1255 26. 73 Mastocytosis - p. 1275 27. 74 Anaphylaxis - p. 1287 28. 75 Insect Allergy - p. 1308 29. 76 Drug Allergy - p. 1325 30. 77 Hypersensitivity to Aspirin and Other Nonsteroidal Antiinflammatory Drugs - p. 1350 31. 78 Reactions to Foods - p. 1361 32. 79 Oral Food Challenge Testing - p. 1395 33. 80 Food Allergy Management, Prevention, and Therapy - p. 1403 34. 81 Adverse Reactions to Vaccines - p. 1430 35. Section H Therapeutics - p. p1453 36. 82 Allergen Immunotherapy for Inhalant Allergens - p. 1453 37. 83 Principles of Pharmacotherapeutics - p. 1486 38. 84 Precision Medicine in Allergic Disorders - p. 1498 39. 85 Optimizing Adherence in Practice - p. 1511 40. 86 Anti-Immunoglobulin E Therapy - p. 1520 41. 87 Cytokine-Specific Therapy in Asthma - p. 1535 42. 88 Histamine and Antihistamines* - p. 1551 43. Contents - p. 1551 44. Introduction - p. 1551 45. Molecular Basis of Histamine Action - p. 1551 46. Histamine Receptors - p. 1553 47. Histamine in Immune Response Regulation - p. 1555 48. Clinical Pharmacology of H1 Antihistamines - p. 1559 49. Allergic Rhinitis - p. 1563 50. Allergic Conjunctivitis - p. 1566 51. Urticaria - p. 1568 52. Other Diseases and Uses - p. 1569 53. Adverse Effects - p. 1571 54. Summary and Future Directions - p. 1576 55. Acknowledgment - p. 1577 56. References - p. 1577 57. 89 Inhaled β2-Agonists - p. 1583 58. Contents - p. 1583 59. Introduction - p. 1583 60. Historical Background - p. 1583 61. Pharmacology of β2-Agonists - p. 1583 62. β2-Receptor Structure and Activation - p. 1584 63. Efficacy of Inhaled β2-Agonists - p. 1585 64. ICS/formoterol Combinations Used as Single-Inhaler Maintenance and Reliever Therapy - p. 1588 65. Conclusion - p. 1588 66. References - p. 1589 67. 90 Anticholinergic Therapies - p. 1591 68. 91 Glucocorticoids - p. 1605 69. 92 Antileukotriene Therapy in Asthma - p. 1630 70. 93 Unconventional Theories and Unproven Methods in Allergy - p. 1646 71. 94 Complementary and Integrative Health - p. 1659 72. CD Molecules - p. 1687 73. Index - p. I1 74. Answers to Self-Assessment Questions - p. page_e1
