MIMS’ Medical Microbiology and Immunology is loved internationally for its thorough yet easy-to-follow coverage of microbiology, infectious diseases, and immunology as a dynamic interplay between microbes and host. Covering the fundamentals of these closely linked disciplines, MIMS’ takes a systems approach to elaborate on epidemiology, clinical presentation, pathogenesis, and diagnostic approaches, as well as treatment and infection control considerations, supplemented by case-based examples. Complex scientific and clinical concepts are explained clearly and simply with the help of illustrations and a range of accompanying online content. Students will come away with a deep understanding of topics and processes, and will return to this book for reference time and again.
1. Introduction - p. ix 2. Contents - p. xii 3. Learning Resources - p. xii 4. Online Cases - p. xii 5. Pathogen Parade - p. xii 6. Vaccine Parade - p. xii 7. Assessments - p. xii 8. Videos - p. xii 9. Section 1 The Adversaries – Pathogens - p. 1 10. 1 Pathogens as parasites - p. 2 11. 2 The bacteria - p. 6 12. 3 The viruses - p. 27 13. 4 The fungi - p. 35 14. 5 The protozoa - p. 40 15. 6 The helminths - p. 43 16. 7 The arthropods - p. 47 17. 8 Prions - p. 50 18. 9 The host–parasite relationship - p. 56 19. Section 2 The adversaries – host defences - p. 67 20. 10 The innate defences of the body - p. 68 21. 11 Adaptive immune responses bring specificity - p. 85 22. 12 Cooperation leads to effective immune responses - p. 97 23. Section 3 The Conflicts - p. 109 24. 13 Background to the infectious diseases - p. 110 25. 14 Entry, exit and transmission - p. 117 26. 15 Immune defences in action - p. 136 27. 16 Spread and replication - p. 152 28. 17 Parasite survival strategies and persistent infections - p. 160 29. 18 Pathologic consequences of infection - p. 176 30. Section 4 Clinical Manifestation and Diagnosis of Infections by Body System - p. 197 31. 19 Upper respiratory tract infections - p. 198 32. 20 Lower respiratory tract infections - p. 214 33. 21 Urinary tract infections - p. 259 34. 22 Sexually transmitted infections - p. 266 35. 23 Gastrointestinal tract infections - p. 291 36. 24 Obstetric and perinatal infections - p. 337 37. 25 Central nervous system infections - p. 347 38. 26 Infections of the eye - p. 367 39. 27 Infections of the skin, soft tissue, muscle and associated systems - p. 374 40. 28 Vectorborne infections - p. 408 41. 29 Multisystem zoonoses - p. 429 42. 30 Fever of unknown origin - p. 444 43. 31 Infections in the compromised host - p. 452 44. Section 5 Diagnosis and Control - p. 467 45. 32 Diagnosis of infection and assessment of host defence mechanisms - p. 468 46. 33 Epidemiology and control of infectious diseases - p. 485 47. 34 Attacking the enemy: antimicrobial agents and chemotherapy - p. 495 48. 35 Protecting the host: vaccination - p. 540 49. 36 Specific and nonspecific immunotherapy - p. 559 50. 37 Infection control - p. 567 51. Index - p. 585 52. Bibliography – list of useful websites - p. e81
MIMS’ Medical Microbiology and Immunology is loved internationally for its thorough yet easy-to-follow coverage of microbiology, infectious diseases, and immunology as a dynamic interplay between microbes and host. Covering the fundamentals of these closely linked disciplines, MIMS’ takes a systems approach to elaborate on epidemiology, clinical presentation, pathogenesis, and diagnostic approaches, as well as treatment and infection control considerations, supplemented by case-based examples. Complex scientific and clinical concepts are explained clearly and simply with the help of illustrations and a range of accompanying online content. Students will come away with a deep understanding of topics and processes, and will return to this book for reference time and again.
1. Introduction - p. ix 2. Contents - p. xii 3. Learning Resources - p. xii 4. Online Cases - p. xii 5. Pathogen Parade - p. xii 6. Vaccine Parade - p. xii 7. Assessments - p. xii 8. Videos - p. xii 9. Section 1 The Adversaries – Pathogens - p. 1 10. 1 Pathogens as parasites - p. 2 11. 2 The bacteria - p. 6 12. 3 The viruses - p. 27 13. 4 The fungi - p. 35 14. 5 The protozoa - p. 40 15. 6 The helminths - p. 43 16. 7 The arthropods - p. 47 17. 8 Prions - p. 50 18. 9 The host–parasite relationship - p. 56 19. Section 2 The adversaries – host defences - p. 67 20. 10 The innate defences of the body - p. 68 21. 11 Adaptive immune responses bring specificity - p. 85 22. 12 Cooperation leads to effective immune responses - p. 97 23. Section 3 The Conflicts - p. 109 24. 13 Background to the infectious diseases - p. 110 25. 14 Entry, exit and transmission - p. 117 26. 15 Immune defences in action - p. 136 27. 16 Spread and replication - p. 152 28. 17 Parasite survival strategies and persistent infections - p. 160 29. 18 Pathologic consequences of infection - p. 176 30. Section 4 Clinical Manifestation and Diagnosis of Infections by Body System - p. 197 31. 19 Upper respiratory tract infections - p. 198 32. 20 Lower respiratory tract infections - p. 214 33. 21 Urinary tract infections - p. 259 34. 22 Sexually transmitted infections - p. 266 35. 23 Gastrointestinal tract infections - p. 291 36. 24 Obstetric and perinatal infections - p. 337 37. 25 Central nervous system infections - p. 347 38. 26 Infections of the eye - p. 367 39. 27 Infections of the skin, soft tissue, muscle and associated systems - p. 374 40. 28 Vectorborne infections - p. 408 41. 29 Multisystem zoonoses - p. 429 42. 30 Fever of unknown origin - p. 444 43. 31 Infections in the compromised host - p. 452 44. Section 5 Diagnosis and Control - p. 467 45. 32 Diagnosis of infection and assessment of host defence mechanisms - p. 468 46. 33 Epidemiology and control of infectious diseases - p. 485 47. 34 Attacking the enemy: antimicrobial agents and chemotherapy - p. 495 48. 35 Protecting the host: vaccination - p. 540 49. 36 Specific and nonspecific immunotherapy - p. 559 50. 37 Infection control - p. 567 51. Index - p. 585 52. Bibliography – list of useful websites - p. e81