MIMS’ Medical Microbiology and Immunology is loved internationally for its thorough yet easy-to-follow coverage of microbiology, infectious diseases, and immunology as a dynamic interplay between microbes and host. Covering the fundamentals of these closely linked disciplines, MIMS’ takes a systems approach to elaborate on epidemiology, clinical presentation, pathogenesis, and diagnostic approaches, as well as treatment and infection control considerations, supplemented by case-based examples. Complex scientific and clinical concepts are explained clearly and simply with the help of illustrations and a range of accompanying online content. Students will come away with a deep understanding of topics and processes, and will return to this book for reference time and again.
1. Introduction - p. ix 2. Contents - p. xii 3. Section 1 The Adversaries – Pathogens - p. 1 4. 1 Pathogens as parasites - p. 2 5. 2 The bacteria - p. 6 6. 3 The viruses - p. 27 7. 4 The fungi - p. 35 8. 5 The protozoa - p. 40 9. 6 The helminths - p. 43 10. 7 The arthropods - p. 47 11. 8 Prions - p. 50 12. 9 The host–parasite relationship - p. 56 13. Section 2 The adversaries – host defences - p. 67 14. 10 The innate defences of the body - p. 68 15. 11 Adaptive immune responses bring specificity - p. 85 16. 12 Cooperation leads to effective immune responses - p. 97 17. Section 3 The Conflicts - p. 109 18. 13 Background to the infectious diseases - p. 110 19. 14 Entry, exit and transmission - p. 117 20. 15 Immune defences in action - p. 136 21. 16 Spread and replication - p. 152 22. 17 Parasite survival strategies and persistent infections - p. 160 23. 18 Pathologic consequences of infection - p. 176 24. Section 4 Clinical Manifestation and Diagnosis of Infections by Body System - p. 197 25. 19 Upper respiratory tract infections - p. 198 26. 20 Lower respiratory tract infections - p. 214 27. 21 Urinary tract infections - p. 259 28. 22 Sexually transmitted infections - p. 266 29. 23 Gastrointestinal tract infections - p. 291 30. 24 Obstetric and perinatal infections - p. 337 31. 25 Central nervous system infections - p. 347 32. 26 Infections of the eye - p. 367 33. 27 Infections of the skin, soft tissue, muscle and associated systems - p. 374 34. 28 Vectorborne infections - p. 408 35. 29 Multisystem zoonoses - p. 429 36. 30 Fever of unknown origin - p. 444 37. 31 Infections in the compromised host - p. 452 38. Section 5 Diagnosis and Control - p. 467 39. 32 Diagnosis of infection and assessment of host defence mechanisms - p. 468 40. 33 Epidemiology and control of infectious diseases - p. 485 41. 34 Attacking the enemy: antimicrobial agents and chemotherapy - p. 495 42. 35 Protecting the host: vaccination - p. 540 43. 36 Specific and nonspecific immunotherapy - p. 559 44. 37 Infection control - p. 567 45. Index - p. 585 46. Pathogen parade - p. e1 47. Vaccine parade - p. e46 48. Section 1: The Adversaries—Pathogens - p. e52 49. Section 2: The Adversaries—Host Defences - p. e55 50. Section 3: The Conflicts - p. e57 51. Section 4: Clinical Manifestation and Diagnosis of Infections by Body System - p. e61 52. Section 5: Diagnosis and Control - p. e71 53. Online Cases - p. e75 54. Bibliography – list of useful websites - p. e81
MIMS’ Medical Microbiology and Immunology is loved internationally for its thorough yet easy-to-follow coverage of microbiology, infectious diseases, and immunology as a dynamic interplay between microbes and host. Covering the fundamentals of these closely linked disciplines, MIMS’ takes a systems approach to elaborate on epidemiology, clinical presentation, pathogenesis, and diagnostic approaches, as well as treatment and infection control considerations, supplemented by case-based examples. Complex scientific and clinical concepts are explained clearly and simply with the help of illustrations and a range of accompanying online content. Students will come away with a deep understanding of topics and processes, and will return to this book for reference time and again.
1. Introduction - p. ix 2. Contents - p. xii 3. Section 1 The Adversaries – Pathogens - p. 1 4. 1 Pathogens as parasites - p. 2 5. 2 The bacteria - p. 6 6. 3 The viruses - p. 27 7. 4 The fungi - p. 35 8. 5 The protozoa - p. 40 9. 6 The helminths - p. 43 10. 7 The arthropods - p. 47 11. 8 Prions - p. 50 12. 9 The host–parasite relationship - p. 56 13. Section 2 The adversaries – host defences - p. 67 14. 10 The innate defences of the body - p. 68 15. 11 Adaptive immune responses bring specificity - p. 85 16. 12 Cooperation leads to effective immune responses - p. 97 17. Section 3 The Conflicts - p. 109 18. 13 Background to the infectious diseases - p. 110 19. 14 Entry, exit and transmission - p. 117 20. 15 Immune defences in action - p. 136 21. 16 Spread and replication - p. 152 22. 17 Parasite survival strategies and persistent infections - p. 160 23. 18 Pathologic consequences of infection - p. 176 24. Section 4 Clinical Manifestation and Diagnosis of Infections by Body System - p. 197 25. 19 Upper respiratory tract infections - p. 198 26. 20 Lower respiratory tract infections - p. 214 27. 21 Urinary tract infections - p. 259 28. 22 Sexually transmitted infections - p. 266 29. 23 Gastrointestinal tract infections - p. 291 30. 24 Obstetric and perinatal infections - p. 337 31. 25 Central nervous system infections - p. 347 32. 26 Infections of the eye - p. 367 33. 27 Infections of the skin, soft tissue, muscle and associated systems - p. 374 34. 28 Vectorborne infections - p. 408 35. 29 Multisystem zoonoses - p. 429 36. 30 Fever of unknown origin - p. 444 37. 31 Infections in the compromised host - p. 452 38. Section 5 Diagnosis and Control - p. 467 39. 32 Diagnosis of infection and assessment of host defence mechanisms - p. 468 40. 33 Epidemiology and control of infectious diseases - p. 485 41. 34 Attacking the enemy: antimicrobial agents and chemotherapy - p. 495 42. 35 Protecting the host: vaccination - p. 540 43. 36 Specific and nonspecific immunotherapy - p. 559 44. 37 Infection control - p. 567 45. Index - p. 585 46. Pathogen parade - p. e1 47. Vaccine parade - p. e46 48. Section 1: The Adversaries—Pathogens - p. e52 49. Section 2: The Adversaries—Host Defences - p. e55 50. Section 3: The Conflicts - p. e57 51. Section 4: Clinical Manifestation and Diagnosis of Infections by Body System - p. e61 52. Section 5: Diagnosis and Control - p. e71 53. Online Cases - p. e75 54. Bibliography – list of useful websites - p. e81
