Mitochondrial Signaling and Regulation: Immune Responses and Diseases delves into the latest research on molecular pathophysiology mechanisms and cell signaling pathways in the pathogenesis of diseases via mitochondrial regulation. This comprehensive study underscores the importance of mitochondria in cellular processes and their role in disease development. Early chapters discuss the crucial role, regulation, and crosstalk of mitochondria, highlighting their significance in maintaining cellular health. The exploration of mitochondria mutations and mitochondria-related diseases follows, providing a detailed understanding of the genetic aspects involved.
Final chapters focus on mitochondria's involvement in immune responses and allegro-inflammation, presenting the intricate connections between mitochondrial function and the immune system. The book also explores the use of biotechnology in developing new treatments and targeted therapies against mitochondrial dysfunction. This resource sets the foundation for new classifications, prevention methods, therapies, and treatments of mitochondria-related diseases, making it invaluable for scientists and researchers dedicated to this field.
1. 10.1 Introduction - p. 249 2. 10.2 Asthma - p. 251 3. 10.3 Unveiling a new player - p. 256 4. 10.4 Impact of mitochondrial dysfunction on different cell types in asthma - p. 287 5. 10.5 Mitochondria, obesity, and asthma - p. 299 6. 10.6 Therapeutic potential of mitochondrial targeting - p. 301 7. 10.7 Conclusion - p. 321 8. References - p. 321 9. Chapter 11. Mitochondria in immune cells: their role in immunity, inflammation, and metabolism - p. 363 10. Abstract - p. 363 11. 11.1 Introduction - p. 363 12. 11.2 Mitochondria in lymphocytes: essential regulators of activation, metabolism, and fate determination - p. 364 13. 11.3 Mitochondrial dysfunction and immune dysregulation - p. 366 14. 11.4 Mitochondria in B lymphocytes: roles in immune activation, proliferation, and differentiation - p. 367 15. 11.5 Mitochondria in T lymphocytes: roles in immune activation, metabolism, and differentiation - p. 370 16. 11.6 Mitochondria in natural killer cells: implications for immune function and regulation - p. 373 17. 11.7 Mitochondria in natural killer T cells: role in immunity and metabolic regulation - p. 377 18. 11.8 Mitochondria in monocytes and macrophages: regulators of immune function, metabolism, and inflammation - p. 380 19. 11.9 Mitochondria in eosinophils: cellular energy, activation, and inflammatory response - p. 383 20. 11.10 Mitochondria in basophils: energy production, inflammatory response, and immune regulation - p. 386 21. 11.11 Mitochondria in mast cells: energy metabolism, degranulation, and immune regulation - p. 389 22. 11.12 Mitochondria in neutrophils: metabolism, reactive oxygen species production, and immune function - p. 393 23. 11.13 Mitochondria in dendritic cells: metabolism, immune activation, and immune tolerance - p. 396 24. 11.14 Mitochondria in megakaryocytes: roles in energy metabolism, platelet production, and hemostasis - p. 399 25. 11.15 Mitochondria in erythroblasts: roles in energy metabolism, hemoglobin synthesis, and erythropoiesis - p. 402 26. 11.16 Mitochondria in hematopoietic stem cells: metabolism, function, and regulation - p. 405 27. 11.17 Mitochondria in plasma cells: function, dynamics, and implications - p. 409 28. 11.18 Mitochondria in chimeric antigen receptor T cells: role in function, metabolism, and persistence - p. 413 29. 11.19 Mitochondria in chimeric antigen receptor natural killer cells: metabolic regulation and functional implications - p. 418 30. 11.20 Mitochondria in chimeric antigen receptor natural killer T cells: metabolic reprogramming and functional implications - p. 423 31. 11.21 Cytokine-releasing cells and mitochondria - p. 430 32. 11.22 Cytokine receptors and mitochondria - p. 433 33. 11.23 Mitochondria and chemokine-releasing cells: interconnections and roles in immune responses - p. 436 34. 11.24 Chemokine receptors and mitochondria - p. 439 35. 11.25 Cell communications and mitochondria - p. 442 36. 11.26 Cluster of differentiation markers and mitochondria - p. 445 37. 11.27 Immune cell receptors and mitochondria - p. 448 38. 11.28 Mitochondrial signaling in immune cells - p. 451 39. 11.29 Cell signaling relationships with mitochondrial signaling - p. 458 40. 11.30 Phagocytosis and mitochondria - p. 471 41. 11.31 Pinocytosis and mitochondria - p. 475 42. 11.32 Endocytosis and mitochondria - p. 478 43. 11.33 Mitochondria and gene expression - p. 482 44. 11.34 The role of mitochondria in cell cross-talk - p. 489 45. 11.35 The role of mitochondria in immune cell memory - p. 495 46. References - p. 501 47. Index - p. 531
Mitochondrial Signaling and Regulation: Immune Responses and Diseases delves into the latest research on molecular pathophysiology mechanisms and cell signaling pathways in the pathogenesis of diseases via mitochondrial regulation. This comprehensive study underscores the importance of mitochondria in cellular processes and their role in disease development. Early chapters discuss the crucial role, regulation, and crosstalk of mitochondria, highlighting their significance in maintaining cellular health. The exploration of mitochondria mutations and mitochondria-related diseases follows, providing a detailed understanding of the genetic aspects involved.
Final chapters focus on mitochondria's involvement in immune responses and allegro-inflammation, presenting the intricate connections between mitochondrial function and the immune system. The book also explores the use of biotechnology in developing new treatments and targeted therapies against mitochondrial dysfunction. This resource sets the foundation for new classifications, prevention methods, therapies, and treatments of mitochondria-related diseases, making it invaluable for scientists and researchers dedicated to this field.
1. 10.1 Introduction - p. 249 2. 10.2 Asthma - p. 251 3. 10.3 Unveiling a new player - p. 256 4. 10.4 Impact of mitochondrial dysfunction on different cell types in asthma - p. 287 5. 10.5 Mitochondria, obesity, and asthma - p. 299 6. 10.6 Therapeutic potential of mitochondrial targeting - p. 301 7. 10.7 Conclusion - p. 321 8. References - p. 321 9. Chapter 11. Mitochondria in immune cells: their role in immunity, inflammation, and metabolism - p. 363 10. Abstract - p. 363 11. 11.1 Introduction - p. 363 12. 11.2 Mitochondria in lymphocytes: essential regulators of activation, metabolism, and fate determination - p. 364 13. 11.3 Mitochondrial dysfunction and immune dysregulation - p. 366 14. 11.4 Mitochondria in B lymphocytes: roles in immune activation, proliferation, and differentiation - p. 367 15. 11.5 Mitochondria in T lymphocytes: roles in immune activation, metabolism, and differentiation - p. 370 16. 11.6 Mitochondria in natural killer cells: implications for immune function and regulation - p. 373 17. 11.7 Mitochondria in natural killer T cells: role in immunity and metabolic regulation - p. 377 18. 11.8 Mitochondria in monocytes and macrophages: regulators of immune function, metabolism, and inflammation - p. 380 19. 11.9 Mitochondria in eosinophils: cellular energy, activation, and inflammatory response - p. 383 20. 11.10 Mitochondria in basophils: energy production, inflammatory response, and immune regulation - p. 386 21. 11.11 Mitochondria in mast cells: energy metabolism, degranulation, and immune regulation - p. 389 22. 11.12 Mitochondria in neutrophils: metabolism, reactive oxygen species production, and immune function - p. 393 23. 11.13 Mitochondria in dendritic cells: metabolism, immune activation, and immune tolerance - p. 396 24. 11.14 Mitochondria in megakaryocytes: roles in energy metabolism, platelet production, and hemostasis - p. 399 25. 11.15 Mitochondria in erythroblasts: roles in energy metabolism, hemoglobin synthesis, and erythropoiesis - p. 402 26. 11.16 Mitochondria in hematopoietic stem cells: metabolism, function, and regulation - p. 405 27. 11.17 Mitochondria in plasma cells: function, dynamics, and implications - p. 409 28. 11.18 Mitochondria in chimeric antigen receptor T cells: role in function, metabolism, and persistence - p. 413 29. 11.19 Mitochondria in chimeric antigen receptor natural killer cells: metabolic regulation and functional implications - p. 418 30. 11.20 Mitochondria in chimeric antigen receptor natural killer T cells: metabolic reprogramming and functional implications - p. 423 31. 11.21 Cytokine-releasing cells and mitochondria - p. 430 32. 11.22 Cytokine receptors and mitochondria - p. 433 33. 11.23 Mitochondria and chemokine-releasing cells: interconnections and roles in immune responses - p. 436 34. 11.24 Chemokine receptors and mitochondria - p. 439 35. 11.25 Cell communications and mitochondria - p. 442 36. 11.26 Cluster of differentiation markers and mitochondria - p. 445 37. 11.27 Immune cell receptors and mitochondria - p. 448 38. 11.28 Mitochondrial signaling in immune cells - p. 451 39. 11.29 Cell signaling relationships with mitochondrial signaling - p. 458 40. 11.30 Phagocytosis and mitochondria - p. 471 41. 11.31 Pinocytosis and mitochondria - p. 475 42. 11.32 Endocytosis and mitochondria - p. 478 43. 11.33 Mitochondria and gene expression - p. 482 44. 11.34 The role of mitochondria in cell cross-talk - p. 489 45. 11.35 The role of mitochondria in immune cell memory - p. 495 46. References - p. 501 47. Index - p. 531
