Modeling of Mass Transport Processes in Biological Media focuses on applications of mass transfer relevant to biomedical processes and technology—fields that require quantitative mechanistic descriptions of the delivery of molecules and drugs. This book features recent advances and developments in biomedical therapies with a focus on the associated theoretical and mathematical techniques necessary to predict mass transfer in biological systems.
The book is authored by over 50 established researchers who are internationally recognized as leaders in their fields. Each chapter contains a comprehensive introductory section for those new to the field, followed by recent modeling developments motivated by empirical experimental observation. Offering a unique opportunity for the reader to access recent developments from technical, theoretical, and engineering perspectives, this book is ideal for graduate and postdoctoral researchers in academia as well as experienced researchers in biomedical industries.
1. 5.1 Introduction - p. 88 2. 5.2 Formulation of the problem - p. 95 3. 5.3 Method of solution - p. 100 4. 5.4 Case study: A 3D rectangular biological tissue - p. 106 5. 5.5 Results and discussion - p. 124 6. 5.6 Conclusions - p. 123 7. 5.A Appendix A - p. 127 8. 5.B Appendix B - p. 126 9. 5.C Appendix C - p. 129 10. 5.D Appendix D - p. 129 11. 5.E Appendix E - p. 131 12. References - p. 133 13. Chapter 6. Computational investigation of the role of low-density lipoprotein and oxygen transport in atherosclerotic arteries - p. 152 14. Chapter 7. Fluid dynamics and mass transport in lower limb vessels: Effects on restenosis - p. 223 15. Chapter 8. Numerical modeling in support of locoregional drug delivery during transarterial therapies for liver cancer - p. 259 16. Chapter 9. Active gel: A continuum physics perspective - p. 287 17. Chapter 10. Modeling nasal spray droplet deposition and translocation in nasal airway for olfactory delivery - p. 311 18. Chapter 11. Drug delivery and in vivo absorption - p. 335 19. Chapter 12. Modeling the physiological phenomena and the effects of therapy on the dynamics of tumor growth - p. 391 20. Chapter 13. Mathematical models of water transport across ocular epithelial layers - p. 405 21. Chapter 14. Multidimensional modeling of solid tumor proliferation following drug treatment: Toward computational prognosis as a tool to support oncology - p. 435 22. Chapter 15. Modeling LDL accumulation within an arterial wall - p. 455 23. Chapter 16. Modeling transport of soluble proteins and metabolites in the brain - p. 493 24. Chapter 17. Hybrid-dimensional models for blood flow and mass transport: Sequential and embedded 3D-1D models - p. 509 25. Chapter 18. Chemical thermodynamic principles and computational modeling of NOX2-mediated ROS production on cell membrane - p. 537 26. Index - p. 581
Modeling of Mass Transport Processes in Biological Media focuses on applications of mass transfer relevant to biomedical processes and technology—fields that require quantitative mechanistic descriptions of the delivery of molecules and drugs. This book features recent advances and developments in biomedical therapies with a focus on the associated theoretical and mathematical techniques necessary to predict mass transfer in biological systems.
The book is authored by over 50 established researchers who are internationally recognized as leaders in their fields. Each chapter contains a comprehensive introductory section for those new to the field, followed by recent modeling developments motivated by empirical experimental observation. Offering a unique opportunity for the reader to access recent developments from technical, theoretical, and engineering perspectives, this book is ideal for graduate and postdoctoral researchers in academia as well as experienced researchers in biomedical industries.
1. 5.1 Introduction - p. 88 2. 5.2 Formulation of the problem - p. 95 3. 5.3 Method of solution - p. 100 4. 5.4 Case study: A 3D rectangular biological tissue - p. 106 5. 5.5 Results and discussion - p. 124 6. 5.6 Conclusions - p. 123 7. 5.A Appendix A - p. 127 8. 5.B Appendix B - p. 126 9. 5.C Appendix C - p. 129 10. 5.D Appendix D - p. 129 11. 5.E Appendix E - p. 131 12. References - p. 133 13. Chapter 6. Computational investigation of the role of low-density lipoprotein and oxygen transport in atherosclerotic arteries - p. 152 14. Chapter 7. Fluid dynamics and mass transport in lower limb vessels: Effects on restenosis - p. 223 15. Chapter 8. Numerical modeling in support of locoregional drug delivery during transarterial therapies for liver cancer - p. 259 16. Chapter 9. Active gel: A continuum physics perspective - p. 287 17. Chapter 10. Modeling nasal spray droplet deposition and translocation in nasal airway for olfactory delivery - p. 311 18. Chapter 11. Drug delivery and in vivo absorption - p. 335 19. Chapter 12. Modeling the physiological phenomena and the effects of therapy on the dynamics of tumor growth - p. 391 20. Chapter 13. Mathematical models of water transport across ocular epithelial layers - p. 405 21. Chapter 14. Multidimensional modeling of solid tumor proliferation following drug treatment: Toward computational prognosis as a tool to support oncology - p. 435 22. Chapter 15. Modeling LDL accumulation within an arterial wall - p. 455 23. Chapter 16. Modeling transport of soluble proteins and metabolites in the brain - p. 493 24. Chapter 17. Hybrid-dimensional models for blood flow and mass transport: Sequential and embedded 3D-1D models - p. 509 25. Chapter 18. Chemical thermodynamic principles and computational modeling of NOX2-mediated ROS production on cell membrane - p. 537 26. Index - p. 581
