Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts on management of high grade glioma. Some of the articles in this issue include: Use of language mapping to aid resection of eloquent gliomas; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Nanotechnology potential applications for GBM therapy; High Grade Gliomas in children; Modern Advances in Brain Tumor Treatments; Molecular pathways of Avastin interactions for the treatment of glioblastoma; and Quality of Life and Outcomes in Glioblastoma management.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. Forthcoming Issues - p. 5 6. Modern Management of High Grade Glioma, Part II - p. 6 7. Immunotherapy for Glioma - p. 7 8. Glioblastoma Multiforme Treatment with Clinical Trials for Surgical Resection (Aminolevulinic Acid) - p. 20 9. Potential Role for STAT3 Inhibitors in Glioblastoma - p. 24 10. CD133 as a Marker for Regulation and Potential for Targeted Therapies in Glioblastoma Multiforme - p. 33 11. Clinical Trials of Small Molecule Inhibitors in High-Grade Glioma - p. 43 12. Molecular Characteristics and Pathways of Avastin for the Treatment of Glioblastoma Multiforme - p. 51 13. Potential Usefulness of Radiosensitizers in Glioblastoma - p. 60 14. Nanotechnology Applications for Glioblastoma - p. 67 15. Endogenous Vaults and Bioengineered Vault Nanoparticles for Treatment of Glioblastomas - p. 77 16. Clinical Trials with Immunotherapy for High-Grade Glioma - p. 84 17. IDH Mutations in Human Glioma - p. 94 18. Passive Immunotherapeutic Strategies for the Treatment of Malignant Gliomas - p. 102 19. Use of Language Mapping to Aid in Resection of Gliomas in Eloquent Brain Regions - p. 113 20. Quality of Life and Outcomes in Glioblastoma Management - p. 119 21. High-Grade Gliomas in Children - p. 124 22. Index - p. 130
Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts on management of high grade glioma. Some of the articles in this issue include: Use of language mapping to aid resection of eloquent gliomas; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Nanotechnology potential applications for GBM therapy; High Grade Gliomas in children; Modern Advances in Brain Tumor Treatments; Molecular pathways of Avastin interactions for the treatment of glioblastoma; and Quality of Life and Outcomes in Glioblastoma management.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. Forthcoming Issues - p. 5 6. Modern Management of High Grade Glioma, Part II - p. 6 7. Immunotherapy for Glioma - p. 7 8. Glioblastoma Multiforme Treatment with Clinical Trials for Surgical Resection (Aminolevulinic Acid) - p. 20 9. Potential Role for STAT3 Inhibitors in Glioblastoma - p. 24 10. CD133 as a Marker for Regulation and Potential for Targeted Therapies in Glioblastoma Multiforme - p. 33 11. Clinical Trials of Small Molecule Inhibitors in High-Grade Glioma - p. 43 12. Molecular Characteristics and Pathways of Avastin for the Treatment of Glioblastoma Multiforme - p. 51 13. Potential Usefulness of Radiosensitizers in Glioblastoma - p. 60 14. Nanotechnology Applications for Glioblastoma - p. 67 15. Endogenous Vaults and Bioengineered Vault Nanoparticles for Treatment of Glioblastomas - p. 77 16. Clinical Trials with Immunotherapy for High-Grade Glioma - p. 84 17. IDH Mutations in Human Glioma - p. 94 18. Passive Immunotherapeutic Strategies for the Treatment of Malignant Gliomas - p. 102 19. Use of Language Mapping to Aid in Resection of Gliomas in Eloquent Brain Regions - p. 113 20. Quality of Life and Outcomes in Glioblastoma Management - p. 119 21. High-Grade Gliomas in Children - p. 124 22. Index - p. 130