The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.Molecular Players in iPSC Technology, Volume 12 addresses the molecular players underlying induced pluripotent stem cell (iPSC) generation, maintenance, expansion, and differentiation. The discovery of iPSCs revolutionized biomedical research. iPSC technology involves multiple molecular mechanisms. This volume covers exosomal microRNAs, auxiliary pluripotency-associated genes, inducible caspase-9 suicide gene, cell cycle proteins, ion channels, Notch signaling, kinase signaling, SOCS3/JAK2/STAT3 pathway, NANOG, Krüppel-like factors, H1FOO, and much more in iPSCs. The volume is written for researchers and scientists in stem cell therapy, cellular and molecular biology, and regenerative medicine and is contributed by world-renowned authors in the field.
1. Molecular Players in iPSC Technology, Volume 12 - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Advances in Stem Cell Biology - p. Page iv 6. Copyright - p. Page v 7. Dedication - p. Page vi 8. Contributors - p. Page vi 9. About the editor - p. Page x 10. Preface - p. Page x 11. List of Illustrations - p. Page xii 12. List of Tables - p. Page xiii 13. Chapter 1 : Engineering exosomal microRNAs in human pluripotent stem cells - p. Page xiii 14. Chapter 2 : Auxiliary pluripotency-associated genes and their contributions in the generation of induced pluripotent stem cells - p. Page 19 15. Chapter 3 : Improving the safety of iPSC-derived T cell therapy - p. Page 68 16. Chapter 4 : Induced pluripotency and intrinsic reprogramming factors: adult stem cells versus somatic cells - p. Page 107 17. Chapter 5 : The role of cell cycle in reprogramming toward induced pluripotent stem cells (iPSCs) - p. Page 136 18. Chapter 6 : Signaling pathways regulate cardiovascular lineage commitment of hPSCs - p. Page 185 19. Chapter 7 : Role of ion channels in human induced pluripotent stem cells–derived cardiomyocytes - p. Page 208 20. Chapter 8 : Notch signaling in induced pluripotent stem cells - p. Page 240 21. Chapter 9 : The extracellular signal-regulated kinase signaling pathway in biology of pluripotent stem cells - p. Page 276 22. Chapter 10 : SOCS3/JAK2/STAT3 pathway in iPSCs - p. Page 296 23. Chapter 11 : Nanog in iPS cells and during reprogramming∗ - p. Page 313 24. Chapter 12 : The role of Krüppel-like factors in generating induced pluripotent stem cells - p. Page 338 25. Chapter 13 : The oocyte-specific linker histone H1FOO plays a key role in establishing high-quality mouse induced pluripotent stem cells - p. Page 366 26. Index - p. Page 398
The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.Molecular Players in iPSC Technology, Volume 12 addresses the molecular players underlying induced pluripotent stem cell (iPSC) generation, maintenance, expansion, and differentiation. The discovery of iPSCs revolutionized biomedical research. iPSC technology involves multiple molecular mechanisms. This volume covers exosomal microRNAs, auxiliary pluripotency-associated genes, inducible caspase-9 suicide gene, cell cycle proteins, ion channels, Notch signaling, kinase signaling, SOCS3/JAK2/STAT3 pathway, NANOG, Krüppel-like factors, H1FOO, and much more in iPSCs. The volume is written for researchers and scientists in stem cell therapy, cellular and molecular biology, and regenerative medicine and is contributed by world-renowned authors in the field.
1. Molecular Players in iPSC Technology, Volume 12 - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Advances in Stem Cell Biology - p. Page iv 6. Copyright - p. Page v 7. Dedication - p. Page vi 8. Contributors - p. Page vi 9. About the editor - p. Page x 10. Preface - p. Page x 11. List of Illustrations - p. Page xii 12. List of Tables - p. Page xiii 13. Chapter 1 : Engineering exosomal microRNAs in human pluripotent stem cells - p. Page xiii 14. Chapter 2 : Auxiliary pluripotency-associated genes and their contributions in the generation of induced pluripotent stem cells - p. Page 19 15. Chapter 3 : Improving the safety of iPSC-derived T cell therapy - p. Page 68 16. Chapter 4 : Induced pluripotency and intrinsic reprogramming factors: adult stem cells versus somatic cells - p. Page 107 17. Chapter 5 : The role of cell cycle in reprogramming toward induced pluripotent stem cells (iPSCs) - p. Page 136 18. Chapter 6 : Signaling pathways regulate cardiovascular lineage commitment of hPSCs - p. Page 185 19. Chapter 7 : Role of ion channels in human induced pluripotent stem cells–derived cardiomyocytes - p. Page 208 20. Chapter 8 : Notch signaling in induced pluripotent stem cells - p. Page 240 21. Chapter 9 : The extracellular signal-regulated kinase signaling pathway in biology of pluripotent stem cells - p. Page 276 22. Chapter 10 : SOCS3/JAK2/STAT3 pathway in iPSCs - p. Page 296 23. Chapter 11 : Nanog in iPS cells and during reprogramming∗ - p. Page 313 24. Chapter 12 : The role of Krüppel-like factors in generating induced pluripotent stem cells - p. Page 338 25. Chapter 13 : The oocyte-specific linker histone H1FOO plays a key role in establishing high-quality mouse induced pluripotent stem cells - p. Page 366 26. Index - p. Page 398
