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Updated and revised from cover to cover, Moss and Adams' Heart Disease in Infants, Children, and Adolescents: From Fetal Through Adult Life, 11th Edition, provides the authoritative, state-of-the-art information you need when caring for young patients with heart disease. Senior editors Drs. Daniel J. Penny and Frank Cetta lead a diverse and outstanding editorial and author team who cover all recent advances in this complex and fast-changing field. Expert perspectives from leading cardiologists and other members of the cardiac team ensure that this award-winning title remains the reference of choice for cardiology fellows, pediatric cardiologists, and cardiology practitioners worldwide.

1. Cover - p. Cover 2. Title Page - p. iii 3. Copyright - p. iv 4. Dedication - p. v 5. Contributors - p. vii 6. Preface to the Previous Edition - p. xvii 7. Preface - p. xviii 8. Previous Editors - p. xix 9. Contents - p. xx 10. SECTION I: Cardiac Development, Physiology and Epidemiology - p. 1 11. 1 Development of the Heart: Morphogenesis, Growth, and Molecular Regulation of Differentiation - p. 1 12. 2 Epidemiology and Prevention of Congenital Heart Disease - p. 47 13. 3 Genetic Aspects of Congenital Heart Defects - p. 69 14. 4 Postnatal Maturation of Myocardial Structure and Function - p. 92 15. 5 Cardiovascular Physiology - p. 105 16. Section II: Cardiac Diagnostics - p. 119 17. 6 History and Physical Examination - p. 119 18. 7 The Normal Electrocardiogram - p. 136 19. 8 Echocardiography: Basic Principles - p. 153 20. 9 Echocardiographic Assessment of Cardiac Dimensions, Cardiac Function, and Valve Function - p. 185 21. 10 Fetal and Perinatal Cardiology - p. 213 22. 11 Intraoperative and Procedural Echocardiography - p. 252 23. 12 Advanced Echocardiography: 3D, Strain and Stress Echocardiography - p. 284 24. 13 Exercise Stress Testing - p. 306 25. 14 Magnetic Resonance Imaging - p. 323 26. 15 Cardiac Computed Tomography in Children With Congenital Heart Disease - p. 354 27. 16 Cardiac Catheterization and Angiography - p. 380 28. Section III: Cardiovascular Interventions - p. 409 29. 17 Fetal Interventions - p. 409 30. 18 Interventional Cardiac Catheterization - p. 424 31. 19 Surgical Principles and Techniques - p. 479 32. 20 Management of Hematologic Issues in the Cardiac Patient - p. 486 33. 21 Pharmacology - p. 504 34. Section IV: Electrophysiology - p. 529 35. 22 Anatomy of the Cardiac Conduction System in Congenital Heart Disease - p. 529 36. 23 Disorders of Cardiac Rhythm and Conduction - p. 537 37. 24 Cardiac Channelopathies, Syncope, and Sudden Cardiac Death - p. 568 38. 25 Electrophysiology Studies and Electrophysiologic Interventional Catheterization - p. 585 39. Section V: Pediatric Cardiac Intensive Care - p. 615 40. 26 Management of the Preterm Infant With Congenital Heart Disease - p. 615 41. 27 Cardiac Intensive Care - p. 624 42. 28 Cardiac Trauma - p. 663 43. SECTION VI: Congenital Cardiovascular Malformations - p. 671 44. 29 Cardiovascular Anatomy, Terminology and Segmental Approach to Evaluation - p. 671 45. 30 Embryogenesis of Congenital Heart Disease - p. 710 46. PART A: Septal Defects - p. 720 47. 31 Atrial Septal Defects - p. 720 48. 32 Atrioventricular Septal Defects - p. 738 49. 33 Ventricular Septal Defects - p. 763 50. PART B: Arterial Abnormalities - p. 781 51. 34 Patent Ductus Arteriosus and Aortopulmonary Window - p. 781 52. 35 Congenital Anomalies of the Coronary Vessels - p. 797 53. 36 Aortic Arch and Vascular Anomalies - p. 814 54. 37 Abnormalities of the Aortic Root - p. 831 55. PART C: Venous Abnormalities - p. 840 56. 38 Anomalies of the Pulmonary Veins - p. 840 57. 39 Abnormal Systemic Venous Connections - p. 867 58. 40 Vascular Anomalies and Malformations - p. 887 59. PART D: The Right Ventricle - p. 902 60. 41 Ebstein Anomaly and Other Tricuspid Valve Disorders - p. 902 61. 42 Pulmonary Stenosis - p. 928 62. 43 Pulmonary Atresia and Intact Ventricular Septum - p. 950 63. 44 Tetralogy of Fallot With Pulmonary Stenosis, Pulmonary Atresia, and Absent Pulmonary Valve - p. 967 64. PART E: Left Ventricular Inflow and Outflow Abnormalities - p. 996 65. 45 Mitral Valve Abnormalities - p. 996 66. 46 Aortic Stenosis - p. 1019 67. 47 Coarctation of the Aorta - p. 1036 68. 48 Hypoplastic Left Heart Syndrome - p. 1054 69. PART F: Abnormalities of the Origin of the Great Arteries - p. 1076 70. 49 Transposition of the Great Arteries - p. 1076 71. 50 Congenitally Corrected Transposition of the Great Arteries - p. 1097 72. 51 Double-Outlet Right Ventricle - p. 1110 73. 52 Truncus Arteriosus - p. 1123 74. PART G: Complex Cardiac Abnormalities - p. 1136 75. 53 Univentricular Atrioventricular Connection - p. 1136 76. 54 Cardiac Malpositions and Abnormalities of Atrial and Visceral Situs - p. 1155 77. 55 The Fontan Circulation - p. 1180 78. Section VII: Diseases of the Endocardium, Myocardium, and Pericardium - p. 1197 79. 56 Hypertrophic Cardiomyopathy - p. 1197 80. 57 Dilated Cardiomyopathy - p. 1230 81. 58 Excessive Trabeculation of the Cardiac Chambers—Rethinking Ventricular Noncompaction - p. 1243 82. 59 Restrictive Cardiomyopathy - p. 1256 83. 60 Arrhythmogenic Cardiomyopathy - p. 1266 84. 61 Myocarditis - p. 1272 85. 62 Chronic Heart Failure in Children - p. 1289 86. 63 The Heart in Neuromuscular Disorders - p. 1306 87. 64 Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) - p. 1317 88. 65 Acute Rheumatic Fever and Rheumatic Heart Disease - p. 1335 89. 66 Inflammatory and Immune-Mediated Noninfectious Cardiovascular Diseases - p. 1358 90. 67 Cardiac Tumors - p. 1375 91. 68 Pericardial Diseases - p. 1389 92. 69 Infective Endocarditis and Prevention - p. 1403 93. 70 Mechanical Circulatory Support in Children - p. 1419 94. 71 Heart Transplantation - p. 1433 95. Section VIII: Pulmonary Vascular Disease - p. 1453 96. 72 Pathophysiology of Pulmonary Hypertension - p. 1453 97. 73 Pediatric Pulmonary Hypertension - p. 1479 98. Section IX: Children to Adults—A Lifespan Perspective - p. 1519 99. 74 Chest Pain in Children and Adolescents - p. 1519 100. 75 Exercise Screening and Sports Participation - p. 1525 101. 76 Cardiovascular Risk Factors in Children - p. 1547 102. 77 Transition to Adult Care - p. 1578 103. 78 The Adolescent and Adult With Congenital Heart Disease - p. 1588 104. 79 Pregnancy in Women With Congenital Heart Disease - p. 1633 105. Section X: Programmatic Approaches to Cardiac Care - p. 1657 106. 80 Teamwork in the Care of Patients With Pediatric and Congenital Heart Disease - p. 1657 107. 81 Neurodevelopmental Outcomes in Congenital Heart Disease - p. 1666 108. 82 Evaluation of Quality of Life in Children and Adolescents With Congenital and Acquired Heart Disease - p. 1673 109. 83 Psychological Impact of Congenital Heart Disease: Key Timestamps and Clinical Strategies - p. 1691 110. 84 Safety and Quality Improvement in Cardiac Care - p. 1698 111. 85 A Global Perspective of Heart Disease - p. 1711 112. 86 Utility of Artificial Intelligence in Pediatric and Adult Structural Heart Disease - p. 1723 113. 87 3D Printing and Extended Reality - p. 1737 114. Index - p. 1755

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Updated and revised from cover to cover, Moss and Adams' Heart Disease in Infants, Children, and Adolescents: From Fetal Through Adult Life, 11th Edition, provides the authoritative, state-of-the-art information you need when caring for young patients with heart disease. Senior editors Drs. Daniel J. Penny and Frank Cetta lead a diverse and outstanding editorial and author team who cover all recent advances in this complex and fast-changing field. Expert perspectives from leading cardiologists and other members of the cardiac team ensure that this award-winning title remains the reference of choice for cardiology fellows, pediatric cardiologists, and cardiology practitioners worldwide.

1. Cover - p. Cover 2. Title Page - p. iii 3. Copyright - p. iv 4. Dedication - p. v 5. Contributors - p. vii 6. Preface to the Previous Edition - p. xvii 7. Preface - p. xviii 8. Previous Editors - p. xix 9. Contents - p. xx 10. SECTION I: Cardiac Development, Physiology and Epidemiology - p. 1 11. 1 Development of the Heart: Morphogenesis, Growth, and Molecular Regulation of Differentiation - p. 1 12. 2 Epidemiology and Prevention of Congenital Heart Disease - p. 47 13. 3 Genetic Aspects of Congenital Heart Defects - p. 69 14. 4 Postnatal Maturation of Myocardial Structure and Function - p. 92 15. 5 Cardiovascular Physiology - p. 105 16. Section II: Cardiac Diagnostics - p. 119 17. 6 History and Physical Examination - p. 119 18. 7 The Normal Electrocardiogram - p. 136 19. 8 Echocardiography: Basic Principles - p. 153 20. 9 Echocardiographic Assessment of Cardiac Dimensions, Cardiac Function, and Valve Function - p. 185 21. 10 Fetal and Perinatal Cardiology - p. 213 22. 11 Intraoperative and Procedural Echocardiography - p. 252 23. 12 Advanced Echocardiography: 3D, Strain and Stress Echocardiography - p. 284 24. 13 Exercise Stress Testing - p. 306 25. 14 Magnetic Resonance Imaging - p. 323 26. 15 Cardiac Computed Tomography in Children With Congenital Heart Disease - p. 354 27. 16 Cardiac Catheterization and Angiography - p. 380 28. Section III: Cardiovascular Interventions - p. 409 29. 17 Fetal Interventions - p. 409 30. 18 Interventional Cardiac Catheterization - p. 424 31. 19 Surgical Principles and Techniques - p. 479 32. 20 Management of Hematologic Issues in the Cardiac Patient - p. 486 33. 21 Pharmacology - p. 504 34. Section IV: Electrophysiology - p. 529 35. 22 Anatomy of the Cardiac Conduction System in Congenital Heart Disease - p. 529 36. 23 Disorders of Cardiac Rhythm and Conduction - p. 537 37. 24 Cardiac Channelopathies, Syncope, and Sudden Cardiac Death - p. 568 38. 25 Electrophysiology Studies and Electrophysiologic Interventional Catheterization - p. 585 39. Section V: Pediatric Cardiac Intensive Care - p. 615 40. 26 Management of the Preterm Infant With Congenital Heart Disease - p. 615 41. 27 Cardiac Intensive Care - p. 624 42. 28 Cardiac Trauma - p. 663 43. SECTION VI: Congenital Cardiovascular Malformations - p. 671 44. 29 Cardiovascular Anatomy, Terminology and Segmental Approach to Evaluation - p. 671 45. 30 Embryogenesis of Congenital Heart Disease - p. 710 46. PART A: Septal Defects - p. 720 47. 31 Atrial Septal Defects - p. 720 48. 32 Atrioventricular Septal Defects - p. 738 49. 33 Ventricular Septal Defects - p. 763 50. PART B: Arterial Abnormalities - p. 781 51. 34 Patent Ductus Arteriosus and Aortopulmonary Window - p. 781 52. 35 Congenital Anomalies of the Coronary Vessels - p. 797 53. 36 Aortic Arch and Vascular Anomalies - p. 814 54. 37 Abnormalities of the Aortic Root - p. 831 55. PART C: Venous Abnormalities - p. 840 56. 38 Anomalies of the Pulmonary Veins - p. 840 57. 39 Abnormal Systemic Venous Connections - p. 867 58. 40 Vascular Anomalies and Malformations - p. 887 59. PART D: The Right Ventricle - p. 902 60. 41 Ebstein Anomaly and Other Tricuspid Valve Disorders - p. 902 61. 42 Pulmonary Stenosis - p. 928 62. 43 Pulmonary Atresia and Intact Ventricular Septum - p. 950 63. 44 Tetralogy of Fallot With Pulmonary Stenosis, Pulmonary Atresia, and Absent Pulmonary Valve - p. 967 64. PART E: Left Ventricular Inflow and Outflow Abnormalities - p. 996 65. 45 Mitral Valve Abnormalities - p. 996 66. 46 Aortic Stenosis - p. 1019 67. 47 Coarctation of the Aorta - p. 1036 68. 48 Hypoplastic Left Heart Syndrome - p. 1054 69. PART F: Abnormalities of the Origin of the Great Arteries - p. 1076 70. 49 Transposition of the Great Arteries - p. 1076 71. 50 Congenitally Corrected Transposition of the Great Arteries - p. 1097 72. 51 Double-Outlet Right Ventricle - p. 1110 73. 52 Truncus Arteriosus - p. 1123 74. PART G: Complex Cardiac Abnormalities - p. 1136 75. 53 Univentricular Atrioventricular Connection - p. 1136 76. 54 Cardiac Malpositions and Abnormalities of Atrial and Visceral Situs - p. 1155 77. 55 The Fontan Circulation - p. 1180 78. Section VII: Diseases of the Endocardium, Myocardium, and Pericardium - p. 1197 79. 56 Hypertrophic Cardiomyopathy - p. 1197 80. 57 Dilated Cardiomyopathy - p. 1230 81. 58 Excessive Trabeculation of the Cardiac Chambers—Rethinking Ventricular Noncompaction - p. 1243 82. 59 Restrictive Cardiomyopathy - p. 1256 83. 60 Arrhythmogenic Cardiomyopathy - p. 1266 84. 61 Myocarditis - p. 1272 85. 62 Chronic Heart Failure in Children - p. 1289 86. 63 The Heart in Neuromuscular Disorders - p. 1306 87. 64 Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) - p. 1317 88. 65 Acute Rheumatic Fever and Rheumatic Heart Disease - p. 1335 89. 66 Inflammatory and Immune-Mediated Noninfectious Cardiovascular Diseases - p. 1358 90. 67 Cardiac Tumors - p. 1375 91. 68 Pericardial Diseases - p. 1389 92. 69 Infective Endocarditis and Prevention - p. 1403 93. 70 Mechanical Circulatory Support in Children - p. 1419 94. 71 Heart Transplantation - p. 1433 95. Section VIII: Pulmonary Vascular Disease - p. 1453 96. 72 Pathophysiology of Pulmonary Hypertension - p. 1453 97. 73 Pediatric Pulmonary Hypertension - p. 1479 98. Section IX: Children to Adults—A Lifespan Perspective - p. 1519 99. 74 Chest Pain in Children and Adolescents - p. 1519 100. 75 Exercise Screening and Sports Participation - p. 1525 101. 76 Cardiovascular Risk Factors in Children - p. 1547 102. 77 Transition to Adult Care - p. 1578 103. 78 The Adolescent and Adult With Congenital Heart Disease - p. 1588 104. 79 Pregnancy in Women With Congenital Heart Disease - p. 1633 105. Section X: Programmatic Approaches to Cardiac Care - p. 1657 106. 80 Teamwork in the Care of Patients With Pediatric and Congenital Heart Disease - p. 1657 107. 81 Neurodevelopmental Outcomes in Congenital Heart Disease - p. 1666 108. 82 Evaluation of Quality of Life in Children and Adolescents With Congenital and Acquired Heart Disease - p. 1673 109. 83 Psychological Impact of Congenital Heart Disease: Key Timestamps and Clinical Strategies - p. 1691 110. 84 Safety and Quality Improvement in Cardiac Care - p. 1698 111. 85 A Global Perspective of Heart Disease - p. 1711 112. 86 Utility of Artificial Intelligence in Pediatric and Adult Structural Heart Disease - p. 1723 113. 87 3D Printing and Extended Reality - p. 1737 114. Index - p. 1755

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