Mucosal Barriers and Host-Microbiota Interplay: Dysbiosis to Barrier Dysfunction, a volume in Elsevier's new series Hot Topics in Physiology, provides an in-depth exploration of mucosal barriers, including their structure, establishment, and consideration of different diseases and intervention strategies. Published in association with the International Union of Physiological Sciences (IUSP), this is an ideal reference for those researching or studying biology and medicine, particularly gastroenterology. Biotechnological companies working on metagenomics sequencing and analysis may also find this volume useful.
As a massive load of commensal microbes, consisting of bacteria, viruses, and fungi resides in the gastrointestinal tract and other mucosal surfaces, collectively termed microbiota, this book provides an update on new and existing knowledge. Mucosal barriers, including the epithelial layers and immune cells act as the frontline to strategically confine these microorganisms and prevent the entry of microbes into the body proper.
1. Title of Book - p. i 2. Cover Image - p. i 3. Title Page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Dedication - p. v 7. Contributors - p. xix 8. About the editor - p. xxi 9. Foreword - p. xxiii 10. Preface - p. xxv 11. Chapter 1 Mucosal barriers and gut microbiota: Traditional concepts and recent advances - p. 1 12. Chapter 2 Neonatal establishment of microbiome ecosystem and intestinal barrier: How developmental programming of gut microbiota impacts health and disease - p. 23 13. Chapter 3 Epithelial junctional proteins for physical defense, cell-cell contact, and polarity complex - p. 51 14. Chapter 4 Unconventional roles of tight junctions in cell survival and ion transport in mucosal barriers - p. 85 15. Chapter 5 Epithelial brush border as a gatekeeper for gut barrier integrity and microbiota eubiosis - p. 107 16. Chapter 6 Wound healing and barrier integrity: Cellular and molecular players in gastric mucosal repair - p. 153 17. Chapter 7 Intraepithelial lymphocytes: Contributions to host–microbiota crosstalk within the epithelial barrier - p. 179 18. Chapter 8 Gut microbiota from health to disease: A role for biofilms? - p. 211 19. Chapter 9 The role of microbiome–mucosal barrier interactions in neoplastic diseases - p. 251 20. Chapter 10 The interplay of gut microbiota and energy homeostasis in obesity-related diseases - p. 299 21. Chapter 11 Refining the role of gut microbiota in the developmental programming of cardiovascular–kidney–metabolic syndrome - p. 325 22. Chapter 12 Interrelationship between intestinal immune cells and barrier function in the development of neurodegenerative diseases - p. 357 23. Chapter 13 Early-life gut infections: Impact on mucosal barriers, neural–immune interactions, and microbiota–gut–brain axis - p. 395 24. Chapter 14 Intestinal epithelial cells: Gatekeepers of the gut–brain axis, microbiome, and beyond - p. 437 25. Chapter 15 The role of gut microbiota in cancer development and translational modulation strategies - p. 465 26. Chapter 16 Diagnostic and therapeutic potentials targeting the interplay of host barriers and microbiota in human gastrointestinal diseases - p. 491 27. Chapter 17 The dietary restoration of intestinal barrier function by nutrient-sensing receptors - p. 535 28. Chapter 18 Dietary factors and next-generation probiotics for microbiota eubiosis and barrier fortification - p. 565 29. Index - p. 593
Mucosal Barriers and Host-Microbiota Interplay: Dysbiosis to Barrier Dysfunction, a volume in Elsevier's new series Hot Topics in Physiology, provides an in-depth exploration of mucosal barriers, including their structure, establishment, and consideration of different diseases and intervention strategies. Published in association with the International Union of Physiological Sciences (IUSP), this is an ideal reference for those researching or studying biology and medicine, particularly gastroenterology. Biotechnological companies working on metagenomics sequencing and analysis may also find this volume useful.
As a massive load of commensal microbes, consisting of bacteria, viruses, and fungi resides in the gastrointestinal tract and other mucosal surfaces, collectively termed microbiota, this book provides an update on new and existing knowledge. Mucosal barriers, including the epithelial layers and immune cells act as the frontline to strategically confine these microorganisms and prevent the entry of microbes into the body proper.
1. Title of Book - p. i 2. Cover Image - p. i 3. Title Page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Dedication - p. v 7. Contributors - p. xix 8. About the editor - p. xxi 9. Foreword - p. xxiii 10. Preface - p. xxv 11. Chapter 1 Mucosal barriers and gut microbiota: Traditional concepts and recent advances - p. 1 12. Chapter 2 Neonatal establishment of microbiome ecosystem and intestinal barrier: How developmental programming of gut microbiota impacts health and disease - p. 23 13. Chapter 3 Epithelial junctional proteins for physical defense, cell-cell contact, and polarity complex - p. 51 14. Chapter 4 Unconventional roles of tight junctions in cell survival and ion transport in mucosal barriers - p. 85 15. Chapter 5 Epithelial brush border as a gatekeeper for gut barrier integrity and microbiota eubiosis - p. 107 16. Chapter 6 Wound healing and barrier integrity: Cellular and molecular players in gastric mucosal repair - p. 153 17. Chapter 7 Intraepithelial lymphocytes: Contributions to host–microbiota crosstalk within the epithelial barrier - p. 179 18. Chapter 8 Gut microbiota from health to disease: A role for biofilms? - p. 211 19. Chapter 9 The role of microbiome–mucosal barrier interactions in neoplastic diseases - p. 251 20. Chapter 10 The interplay of gut microbiota and energy homeostasis in obesity-related diseases - p. 299 21. Chapter 11 Refining the role of gut microbiota in the developmental programming of cardiovascular–kidney–metabolic syndrome - p. 325 22. Chapter 12 Interrelationship between intestinal immune cells and barrier function in the development of neurodegenerative diseases - p. 357 23. Chapter 13 Early-life gut infections: Impact on mucosal barriers, neural–immune interactions, and microbiota–gut–brain axis - p. 395 24. Chapter 14 Intestinal epithelial cells: Gatekeepers of the gut–brain axis, microbiome, and beyond - p. 437 25. Chapter 15 The role of gut microbiota in cancer development and translational modulation strategies - p. 465 26. Chapter 16 Diagnostic and therapeutic potentials targeting the interplay of host barriers and microbiota in human gastrointestinal diseases - p. 491 27. Chapter 17 The dietary restoration of intestinal barrier function by nutrient-sensing receptors - p. 535 28. Chapter 18 Dietary factors and next-generation probiotics for microbiota eubiosis and barrier fortification - p. 565 29. Index - p. 593