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This issue of Physical Medicine and Rehabilitation Clinics, guest edited by Dr. Miriam Segal, will cover the important topic of Muscle Overactivity in Upper Motor Neuron Syndrome, including assessment and problem-solving for complex cases. Topics discussed in the volume will include: Functional/problem based assessment in patients with spinal cord injury; Special considerations in pediatric assessment; Special considerations and assessment of spasticity and multiple sclerosis; Pharmacologic treatment tools; Peripheral neurolysis; The role of physical and occupational therapy; Neurosurgical approaches; The neuro-orthopedic approach; Upper extremity problem-solving: Challenging cases; Lower extremity problem-solving: Challenging cases; and Emerging therapies.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xii 7. Erratum - p. xiii 8. Foreword - p. xv 9. Preface - p. xvii 10. Muscle Overactivity in the Upper Motor Neuron Syndrome: Pathophysiology - p. 427 11. Meaningful Assessment in Patients with Acquired Brain Injuries - p. 437 12. Special Considerations in Assessing and Treating Spasticity in Spinal Cord Injury - p. 445 13. Special Considerations in Pediatric Assessment - p. 455 14. Special Considerations and Assessment in Patients with Multiple Sclerosis - p. 473 15. Muscle Overactivity in the Upper Motor Neuron Syndrome: Conceptualizing a Treatment Plan and Establishing Meaningful Goals - p. 483 16. Pharmacologic Treatment Tools: Systemic Medications and Toxins, Opportunities, and Pitfalls - p. 501 17. Neurolysis: A Brief Review for a Fading Art - p. 519 18. Muscle Overactivity in the Upper Motor Neuron Syndrome: Assessment and Problem Solving for Complex Cases: the Role of Physical and Occupational Therapy - p. 529 19. Intrathecal Therapies - p. 537 20. Neurosurgical Approaches - p. 553 21. The Neuro-Orthopaedic Approach - p. 567 22. Upper Extremity Problem-Solving: Challenging Cases - p. 593 23. Lower Extremity Problem-Solving: Challenging Cases - p. 619 24. Emerging Therapies for Spastic Movement Disorders - p. 633

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This issue of Physical Medicine and Rehabilitation Clinics, guest edited by Dr. Miriam Segal, will cover the important topic of Muscle Overactivity in Upper Motor Neuron Syndrome, including assessment and problem-solving for complex cases. Topics discussed in the volume will include: Functional/problem based assessment in patients with spinal cord injury; Special considerations in pediatric assessment; Special considerations and assessment of spasticity and multiple sclerosis; Pharmacologic treatment tools; Peripheral neurolysis; The role of physical and occupational therapy; Neurosurgical approaches; The neuro-orthopedic approach; Upper extremity problem-solving: Challenging cases; Lower extremity problem-solving: Challenging cases; and Emerging therapies.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xii 7. Erratum - p. xiii 8. Foreword - p. xv 9. Preface - p. xvii 10. Muscle Overactivity in the Upper Motor Neuron Syndrome: Pathophysiology - p. 427 11. Meaningful Assessment in Patients with Acquired Brain Injuries - p. 437 12. Special Considerations in Assessing and Treating Spasticity in Spinal Cord Injury - p. 445 13. Special Considerations in Pediatric Assessment - p. 455 14. Special Considerations and Assessment in Patients with Multiple Sclerosis - p. 473 15. Muscle Overactivity in the Upper Motor Neuron Syndrome: Conceptualizing a Treatment Plan and Establishing Meaningful Goals - p. 483 16. Pharmacologic Treatment Tools: Systemic Medications and Toxins, Opportunities, and Pitfalls - p. 501 17. Neurolysis: A Brief Review for a Fading Art - p. 519 18. Muscle Overactivity in the Upper Motor Neuron Syndrome: Assessment and Problem Solving for Complex Cases: the Role of Physical and Occupational Therapy - p. 529 19. Intrathecal Therapies - p. 537 20. Neurosurgical Approaches - p. 553 21. The Neuro-Orthopaedic Approach - p. 567 22. Upper Extremity Problem-Solving: Challenging Cases - p. 593 23. Lower Extremity Problem-Solving: Challenging Cases - p. 619 24. Emerging Therapies for Spastic Movement Disorders - p. 633

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