Nanoparticle therapeutics: Production Technologies, Types of Nanoparticles, and Regulatory Aspects employs unique principles for applications in cell-based therapeutics, diagnostics and mechanistics for the study of organ physiology, disease etiology and drug screening of advanced nanoparticles and nanomaterials. The book focuses on the extrapolation of bioengineering tools in the domain of nanotechnology and nanoparticles therapeutics, fabrication, characterization and drug delivery aspects. It acquaints scientists and researchers on the experiential and experimental aspects of nanoparticles and nanotechnology to equip their rational application in various fields, especially in differential diagnoses and in the treatment of diverse diseased states.
This complete resource provides a holistic understanding of the principle behind formation, characterization, applications, regulations and toxicity of nanoparticles employing myriad principles of nanotechnology. Investigators, pharmaceutical researchers, and advanced students working on technology advancement in the areas of designing targeted therapies, nanoscale imaging systems and diagnostic modalities in human diseases where nanoparticles can be used as a critical tool for technology advancement in drug delivery systems will find this book useful.
1. Title of Book - p. Cover 2. Cover image - p. Cover 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contributors - p. xi 7. Preface - p. xvii 8. Part 1: Synthesis and characterization of NP for drug delivery - p. xix 9. Chapter 1. Nanoparticle technologies: Recent state of the art and emerging opportunities - p. 4 10. Chapter 2. Fabrication design, process technologies, and convolutions in the scale-up of nanotherapeutic delivery systems - p. 53 11. Chapter 3. In vitro physicochemical characterization of nanocarriers: a road to optimization - p. 139 12. Chapter 4. Surface engineering of nanoparticles for imparting multifunctionality - p. 195 13. Chapter 5. Biofate and cellular interactions of lipid nanoparticles - p. 216 14. Chapter 6. Cellular interactions of nanoparticles within the vasculature - p. 247 15. Chapter 7. Pharmacokinetics and in vivo evaluation of nanoparticles - p. 272 16. Part 2: Application of nanoparticles in drug delivery - p. 289 17. Chapter 8. Biodegradable self-assembled nanocarriers as the drug delivery vehicles - p. 293 18. Chapter 9. Albumin nanoparticles—A versatile and a safe platform for drug delivery applications - p. 327 19. Chapter 10. Silver nanoparticles for biomedical applications - p. 359 20. Chapter 11. Synthesis of silica nanoparticles for biological applications - p. 377 21. Chapter 12. Advances in nanocrystals as drug delivery systems - p. 413 22. Chapter 13. Superparamagnetic iron oxide nanoparticles (SPIONs) as therapeutic and diagnostic agents - p. 464 23. Chapter 14. Bio-inspired nanoparticles as drug delivery vectors - p. 508 24. Chapter 15. Radioactive nanoparticles and their biomedical application in nanobrachytherapy - p. 529 25. Part 3: Environmental and regulatory aspects - p. 560 26. Chapter 16. Regulatory pathways and federal perspectives on nanoparticles - p. 563 27. Chapter 17. Fate and potential hazards of nanoparticles in the environment - p. 591 28. Chapter 18. Biological toxicity of nanoparticles - p. 603 29. Index - p. 629
Nanoparticle therapeutics: Production Technologies, Types of Nanoparticles, and Regulatory Aspects employs unique principles for applications in cell-based therapeutics, diagnostics and mechanistics for the study of organ physiology, disease etiology and drug screening of advanced nanoparticles and nanomaterials. The book focuses on the extrapolation of bioengineering tools in the domain of nanotechnology and nanoparticles therapeutics, fabrication, characterization and drug delivery aspects. It acquaints scientists and researchers on the experiential and experimental aspects of nanoparticles and nanotechnology to equip their rational application in various fields, especially in differential diagnoses and in the treatment of diverse diseased states.
This complete resource provides a holistic understanding of the principle behind formation, characterization, applications, regulations and toxicity of nanoparticles employing myriad principles of nanotechnology. Investigators, pharmaceutical researchers, and advanced students working on technology advancement in the areas of designing targeted therapies, nanoscale imaging systems and diagnostic modalities in human diseases where nanoparticles can be used as a critical tool for technology advancement in drug delivery systems will find this book useful.
1. Title of Book - p. Cover 2. Cover image - p. Cover 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contributors - p. xi 7. Preface - p. xvii 8. Part 1: Synthesis and characterization of NP for drug delivery - p. xix 9. Chapter 1. Nanoparticle technologies: Recent state of the art and emerging opportunities - p. 4 10. Chapter 2. Fabrication design, process technologies, and convolutions in the scale-up of nanotherapeutic delivery systems - p. 53 11. Chapter 3. In vitro physicochemical characterization of nanocarriers: a road to optimization - p. 139 12. Chapter 4. Surface engineering of nanoparticles for imparting multifunctionality - p. 195 13. Chapter 5. Biofate and cellular interactions of lipid nanoparticles - p. 216 14. Chapter 6. Cellular interactions of nanoparticles within the vasculature - p. 247 15. Chapter 7. Pharmacokinetics and in vivo evaluation of nanoparticles - p. 272 16. Part 2: Application of nanoparticles in drug delivery - p. 289 17. Chapter 8. Biodegradable self-assembled nanocarriers as the drug delivery vehicles - p. 293 18. Chapter 9. Albumin nanoparticles—A versatile and a safe platform for drug delivery applications - p. 327 19. Chapter 10. Silver nanoparticles for biomedical applications - p. 359 20. Chapter 11. Synthesis of silica nanoparticles for biological applications - p. 377 21. Chapter 12. Advances in nanocrystals as drug delivery systems - p. 413 22. Chapter 13. Superparamagnetic iron oxide nanoparticles (SPIONs) as therapeutic and diagnostic agents - p. 464 23. Chapter 14. Bio-inspired nanoparticles as drug delivery vectors - p. 508 24. Chapter 15. Radioactive nanoparticles and their biomedical application in nanobrachytherapy - p. 529 25. Part 3: Environmental and regulatory aspects - p. 560 26. Chapter 16. Regulatory pathways and federal perspectives on nanoparticles - p. 563 27. Chapter 17. Fate and potential hazards of nanoparticles in the environment - p. 591 28. Chapter 18. Biological toxicity of nanoparticles - p. 603 29. Index - p. 629
