Nanoscience in Dermatology covers one of the two fastest growing areas within dermatological science, nanoscience and nanotechnology in dermatology. Recently, great progress has been made in the research and development of nanotechnologies and nanomaterials related to various applications in medicine and, in general, the life sciences. There is increasing enthusiasm for nanotechnology applications in dermatology (drug delivery, diagnostics, therapeutics, imaging, sensors, etc.) for understanding skin biology, improving early detection and treatment of skin diseases, and in the design and optimization of cosmetics.
Light sensitive nanoparticles have recently been explored, opening a new era for the combined applications of light with nanotechnology, also called photonanodermatology. However, concerns have been raised regarding the adverse effects of intentional and unintentional nanoparticle exposure and their toxicity.
Written by experts working in these exciting fields, this book extensively covers nanotechnology applications, together with the fundamentals and toxicity aspects. It not only addresses current applications of nanotechnology, but also discusses future trends of these ever-growing and rapidly changing fields, providing scientists and dermatologists with a clear understanding of the advantages and challenges of nanotechnology in skin medicine.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. iii 4. Dedication - p. ii 5. Copyright - p. iv 6. Contributors - p. ix 7. Preface - p. xi 8. Chapter 1. Anatomy and Function of the Skin - p. 1 9. Chapter 2. Fundamentals of Nanoscience (and Nanotechnology) - p. 15 10. Chapter 3. An Overview of Nanomaterials in Dermatology - p. 31 11. Chapter 4. Clinical Impact and Patient Safety: The Potential of Microneedles in Changing the Form and Perception of Transdermal Drug Delivery - p. 47 12. Chapter 5. Inorganic Nanoparticles for Transdermal Drug Delivery and Topical Application - p. 57 13. Chapter 6. Biodegradable, Biocompatible, and Bioconjugate Materials as Delivery Agents in Dermatology: Safe Drug Delivery to Skin - p. 73 14. Chapter 7. Peptide Dendrimers in Delivery of Bioactive Molecules to Skin - p. 89 15. Chapter 8. Insights Into Interactions of Gold Nanoparticles With the Skin and Potential Dermatological Applications - p. 99 16. Chapter 9. Formulation Effects on Topical Nanoparticle Penetration - p. 115 17. Chapter 10. Nitric Oxide–Releasing Nanoparticles as an Antimicrobial Therapeutic - p. 127 18. Chapter 11. Nanoparticles in the Topical Treatment of Cutaneous Leishmaniasis: Gaps, Facts, and Perspectives - p. 135 19. Chapter 12. Nanotechnology-Based Nano-Bullets in Antipsoriatic Drug Delivery: State of the Art - p. 157 20. Chapter 13. Nanoparticles for Treatment of Atopic Dermatitis - p. 167 21. Chapter 14. Challenges and Opportunities of Nanoparticle-Based Theranostics in Skin Cancer - p. 177 22. Chapter 15. Nanodelivery of Anticancer Agents in Melanoma: Encouraging, But a Long Way to Go - p. 189 23. Chapter 16. Targeted Nanoparticles for Drug Delivery to Melanoma: From Bench to Bedside - p. 203 24. Chapter 17. The Potential for Metal Nanoparticle-Enhanced Radiotherapy in Dermatology - p. 217 25. Chapter 18. Nanotechnology in Photoprotection - p. 229 26. Chapter 19. Nanoemulsions to Prevent Photoaging - p. 237 27. Chapter 20. Decoupling Hazard From Risk in Using Sunscreens Containing Metal Oxide Nanoparticles - p. 247 28. Chapter 21. Nanoparticle Oxygen Sensing in Skin - p. 257 29. Chapter 22. Investigating the Intracellular Dynamics of Hypericin-Loaded Nanoparticles and Polyvinylpyrrolidone-Hypericin by Image Correlation Spectroscopy - p. 275 30. Chapter 23. Accelerated Wound Healing Using Nanoparticles - p. 287 31. Chapter 24. Quantum Dot Migration Through Natural Barriers and Distribution in the Skin - p. 307 32. Chapter 25. Nanomedicines for the Eye: Current Status and Future Development - p. 323 33. Chapter 26. Bioinspired Nanotechnologies for Skin Regeneration - p. 337 34. Chapter 27. Imaging Nanoparticle Skin Penetration in Humans - p. 353 35. Chapter 28. EGF-Loaded Nanofibers for Skin Tissue Engineering - p. 367 36. Index - p. 375
Nanoscience in Dermatology covers one of the two fastest growing areas within dermatological science, nanoscience and nanotechnology in dermatology. Recently, great progress has been made in the research and development of nanotechnologies and nanomaterials related to various applications in medicine and, in general, the life sciences. There is increasing enthusiasm for nanotechnology applications in dermatology (drug delivery, diagnostics, therapeutics, imaging, sensors, etc.) for understanding skin biology, improving early detection and treatment of skin diseases, and in the design and optimization of cosmetics.
Light sensitive nanoparticles have recently been explored, opening a new era for the combined applications of light with nanotechnology, also called photonanodermatology. However, concerns have been raised regarding the adverse effects of intentional and unintentional nanoparticle exposure and their toxicity.
Written by experts working in these exciting fields, this book extensively covers nanotechnology applications, together with the fundamentals and toxicity aspects. It not only addresses current applications of nanotechnology, but also discusses future trends of these ever-growing and rapidly changing fields, providing scientists and dermatologists with a clear understanding of the advantages and challenges of nanotechnology in skin medicine.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. iii 4. Dedication - p. ii 5. Copyright - p. iv 6. Contributors - p. ix 7. Preface - p. xi 8. Chapter 1. Anatomy and Function of the Skin - p. 1 9. Chapter 2. Fundamentals of Nanoscience (and Nanotechnology) - p. 15 10. Chapter 3. An Overview of Nanomaterials in Dermatology - p. 31 11. Chapter 4. Clinical Impact and Patient Safety: The Potential of Microneedles in Changing the Form and Perception of Transdermal Drug Delivery - p. 47 12. Chapter 5. Inorganic Nanoparticles for Transdermal Drug Delivery and Topical Application - p. 57 13. Chapter 6. Biodegradable, Biocompatible, and Bioconjugate Materials as Delivery Agents in Dermatology: Safe Drug Delivery to Skin - p. 73 14. Chapter 7. Peptide Dendrimers in Delivery of Bioactive Molecules to Skin - p. 89 15. Chapter 8. Insights Into Interactions of Gold Nanoparticles With the Skin and Potential Dermatological Applications - p. 99 16. Chapter 9. Formulation Effects on Topical Nanoparticle Penetration - p. 115 17. Chapter 10. Nitric Oxide–Releasing Nanoparticles as an Antimicrobial Therapeutic - p. 127 18. Chapter 11. Nanoparticles in the Topical Treatment of Cutaneous Leishmaniasis: Gaps, Facts, and Perspectives - p. 135 19. Chapter 12. Nanotechnology-Based Nano-Bullets in Antipsoriatic Drug Delivery: State of the Art - p. 157 20. Chapter 13. Nanoparticles for Treatment of Atopic Dermatitis - p. 167 21. Chapter 14. Challenges and Opportunities of Nanoparticle-Based Theranostics in Skin Cancer - p. 177 22. Chapter 15. Nanodelivery of Anticancer Agents in Melanoma: Encouraging, But a Long Way to Go - p. 189 23. Chapter 16. Targeted Nanoparticles for Drug Delivery to Melanoma: From Bench to Bedside - p. 203 24. Chapter 17. The Potential for Metal Nanoparticle-Enhanced Radiotherapy in Dermatology - p. 217 25. Chapter 18. Nanotechnology in Photoprotection - p. 229 26. Chapter 19. Nanoemulsions to Prevent Photoaging - p. 237 27. Chapter 20. Decoupling Hazard From Risk in Using Sunscreens Containing Metal Oxide Nanoparticles - p. 247 28. Chapter 21. Nanoparticle Oxygen Sensing in Skin - p. 257 29. Chapter 22. Investigating the Intracellular Dynamics of Hypericin-Loaded Nanoparticles and Polyvinylpyrrolidone-Hypericin by Image Correlation Spectroscopy - p. 275 30. Chapter 23. Accelerated Wound Healing Using Nanoparticles - p. 287 31. Chapter 24. Quantum Dot Migration Through Natural Barriers and Distribution in the Skin - p. 307 32. Chapter 25. Nanomedicines for the Eye: Current Status and Future Development - p. 323 33. Chapter 26. Bioinspired Nanotechnologies for Skin Regeneration - p. 337 34. Chapter 27. Imaging Nanoparticle Skin Penetration in Humans - p. 353 35. Chapter 28. EGF-Loaded Nanofibers for Skin Tissue Engineering - p. 367 36. Index - p. 375