Negative Affective States and Cognitive Impairments in Nicotine Dependence is the only book of its kind that addresses nicotine use and abuse in the context of negative reinforcement mechanisms. Written and edited by leading investigators in addiction, affective, genetic, and cognitive research, it provides researchers and advanced students with an overview of the clinical bases of these effects, allowing them to fully understand the various underlying dysfunctions that drive nicotine use in different individuals. In addition, this book examines animal models that researchers have utilized to investigate the biological bases of these dysfunctions.
The combination of clinical and preclinical approaches to understanding nicotine dependence makes this book an invaluable resource for researchers and practitioners seeking to develop targeted treatments aimed at ameliorating symptoms of nicotine dependence, as well as identifying premorbid differences in affective or cognitive function.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Dedication - p. v 6. List of Contributors - p. xiii 7. Preface - p. xv 8. Acknowledgments - p. xix 9. Chapter 1. Overview of Nicotine Withdrawal and Negative Reinforcement (Preclinical) - p. 1 10. Chapter 2. Nicotine Withdrawal and Attentional Deficit Studies Across Species: Conflation With Attentional Dysfunction in Psychiatric Patients - p. 21 11. Chapter 3. Preclinical Models of Nicotine Withdrawal: Targeting Impaired Cognition - p. 37 12. Chapter 4. Genetic, Developmental, and Receptor-Level Influences on Nicotine Withdrawal-Associated Deficits in Learning - p. 53 13. Chapter 5. Enhanced Tobacco Use Vulnerability in Adolescents, Females, and Persons With Diabetes - p. 71 14. Chapter 6. Detrimental Effects of Prenatal Exposure to Tobacco Smoke and Nicotine - p. 91 15. Chapter 7. Contribution of Translational Genetic Research to Our Understanding of Nicotine Dependence - p. 111 16. Chapter 8. Transmitters and Receptors in Nicotine Withdrawal Syndrome - p. 133 17. Chapter 9. The Cannabinoid System in Nicotine Dependence and Withdrawal - p. 153 18. Chapter 10. Critical Role for Brain Stress Systems in the Negative Affective State Associated With Nicotine Withdrawal - p. 177 19. Chapter 11. The Habenulo-Interpeduncular Pathway and Nicotine Withdrawal - p. 191 20. Chapter 12. A Clinical Overview of Nicotine Dependence and Withdrawal - p. 205 21. Chapter 13. Epidemiologic Research on the Relationship of Nicotine Dependence to Psychiatric and Substance Use Disorders - p. 217 22. Chapter 14. Nicotine and Tobacco Smoking and Withdrawal in Schizophrenia - p. 229 23. Chapter 15. Emergent Cognitive Impairment During Early Nicotine Withdrawal - p. 253 24. Chapter 16. Nicotine and Posttraumatic Stress Disorder - p. 271 25. Chapter 17. Nicotine Withdrawal and Depression: Clinical Studies—A Four-Factor Model for More Accurate Characterization - p. 289 26. Chapter 18. Neuroimaging Insights Into the Multifaceted Nature of the Nicotine Withdrawal Syndrome - p. 311 27. Index - p. 331
Negative Affective States and Cognitive Impairments in Nicotine Dependence is the only book of its kind that addresses nicotine use and abuse in the context of negative reinforcement mechanisms. Written and edited by leading investigators in addiction, affective, genetic, and cognitive research, it provides researchers and advanced students with an overview of the clinical bases of these effects, allowing them to fully understand the various underlying dysfunctions that drive nicotine use in different individuals. In addition, this book examines animal models that researchers have utilized to investigate the biological bases of these dysfunctions.
The combination of clinical and preclinical approaches to understanding nicotine dependence makes this book an invaluable resource for researchers and practitioners seeking to develop targeted treatments aimed at ameliorating symptoms of nicotine dependence, as well as identifying premorbid differences in affective or cognitive function.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Dedication - p. v 6. List of Contributors - p. xiii 7. Preface - p. xv 8. Acknowledgments - p. xix 9. Chapter 1. Overview of Nicotine Withdrawal and Negative Reinforcement (Preclinical) - p. 1 10. Chapter 2. Nicotine Withdrawal and Attentional Deficit Studies Across Species: Conflation With Attentional Dysfunction in Psychiatric Patients - p. 21 11. Chapter 3. Preclinical Models of Nicotine Withdrawal: Targeting Impaired Cognition - p. 37 12. Chapter 4. Genetic, Developmental, and Receptor-Level Influences on Nicotine Withdrawal-Associated Deficits in Learning - p. 53 13. Chapter 5. Enhanced Tobacco Use Vulnerability in Adolescents, Females, and Persons With Diabetes - p. 71 14. Chapter 6. Detrimental Effects of Prenatal Exposure to Tobacco Smoke and Nicotine - p. 91 15. Chapter 7. Contribution of Translational Genetic Research to Our Understanding of Nicotine Dependence - p. 111 16. Chapter 8. Transmitters and Receptors in Nicotine Withdrawal Syndrome - p. 133 17. Chapter 9. The Cannabinoid System in Nicotine Dependence and Withdrawal - p. 153 18. Chapter 10. Critical Role for Brain Stress Systems in the Negative Affective State Associated With Nicotine Withdrawal - p. 177 19. Chapter 11. The Habenulo-Interpeduncular Pathway and Nicotine Withdrawal - p. 191 20. Chapter 12. A Clinical Overview of Nicotine Dependence and Withdrawal - p. 205 21. Chapter 13. Epidemiologic Research on the Relationship of Nicotine Dependence to Psychiatric and Substance Use Disorders - p. 217 22. Chapter 14. Nicotine and Tobacco Smoking and Withdrawal in Schizophrenia - p. 229 23. Chapter 15. Emergent Cognitive Impairment During Early Nicotine Withdrawal - p. 253 24. Chapter 16. Nicotine and Posttraumatic Stress Disorder - p. 271 25. Chapter 17. Nicotine Withdrawal and Depression: Clinical Studies—A Four-Factor Model for More Accurate Characterization - p. 289 26. Chapter 18. Neuroimaging Insights Into the Multifaceted Nature of the Nicotine Withdrawal Syndrome - p. 311 27. Index - p. 331
