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Welcome to the 21st Edition of Nelson Textbook of Pediatrics – the reference of choice among pediatricians, pediatric residents, and others involved in the care of young patients. This fully revised edition continues to provide the breadth and depth of knowledge you expect from Nelson, while also keeping you up to date with new advances in the science and art of pediatric practice. Authoritative and reader-friendly, it delivers the information you need in a concise, easy-to-use format for everyday reference and study. From rapidly changing diagnostic and treatment protocols to new technologies to the wide range of biologic, psychologic, and social problems faced by children today, this comprehensive reference keeps you on the cutting edge of the very best in pediatric care.

  • Includes more than 70 new chapters, including Postural Orthostatic Tachycardia Syndrome (POTS), Rare and Undiagnosed Diseases, Approach to Mitochondrial Disorders, Electronic Nicotine Delivery Systems, Zika, update on Ebola, Epigenetics, Autoimmune Encephalitis, Global Health, Racism, Media Violence, Strategies for Health Behavior Change, Positive Parenting, and many more.
  • Features hundreds of new figures and tables throughout for visual clarity and quick reference.
  • Offers new and expanded information on CRISPR gene editing; LGBT health care; gun violence; vaccinations; immune treatment with CAR-T cells; new technology in imaging and genomics; new protocols in cancer, genetics, immunology, and pulmonary medicine; and much more.
  • Provides fresh perspectives from four new associate editors: Nathan J. Blum of The Children’s Hospital of Philadelphia; Karen Wilson of Mt. Sinai School of Medicine in New York; Samir S. Shah of Cincinnati Children’s Hospital Medical Center; and Robert C. Tasker of Boston Children’s Hospital.
  • Remains your indispensable source for definitive, evidence-based answers on every aspect of pediatric care.

1. Chapter 535: Introduction to Glomerular Diseases - p. g0040 2. Section 2: Conditions Particularly Associated with Hematuria - p. g0040 3. Chapter 536: Clinical Evaluation of the Child With Hematuria - p. g0040 4. Chapter 537: Isolated Glomerular Diseases Associated With Recurrent Gross Hematuria - p. g0040 5. Chapter 538: Multisystem Disease Associated With Hematuria - p. g0040 6. Chapter 539: Tubulointerstitial Disease Associated With Hematuria - p. g0040 7. Chapter 540: Vascular Diseases Associated with Hematuria - p. g0040 8. Chapter 541: Anatomic Abnormalities Associated With Hematuria - p. g0040 9. Chapter 542: Lower Urinary Tract Causes of Hematuria - p. g0040 10. Section 3: Conditions Particularly Associated with Proteinuria - p. g0040 11. Chapter 543: Clinical Evaluation of the Child With Proteinuria - p. g0040 12. Chapter 544: Conditions Associated With Proteinuria - p. g0040 13. Chapter 545: Nephrotic Syndrome - p. g0040 14. Section 4: Tubular Disorders - p. g0040 15. Chapter 546: Tubular Function - p. g0040 16. Chapter 547: Renal Tubular Acidosis - p. g0040 17. Chapter 548: Nephrogenic Diabetes Insipidus - p. g0040 18. Chapter 549: Inherited Tubular Transport Abnormalities - p. g0040 19. Chapter 550: Renal Failure - p. g0040 20. Chapter 551: Renal Transplantation - p. g0040 21. Part XXIII: Urologic Disorders in Infants and Children - p. g0040 22. Chapter 552: Congenital Anomalies and Dysgenesis of the Kidneys - p. g0040 23. Chapter 553: Urinary Tract Infections - p. g0040 24. Chapter 554: Vesicoureteral Reflux - p. g0040 25. Chapter 555: Obstruction of the Urinary Tract - p. g0040 26. Chapter 556: Anomalies of the Bladder - p. g0040 27. Chapter 557: Neuropathic Bladder - p. g0040 28. Chapter 558: Enuresis and Voiding Dysfunction - p. g0040 29. Chapter 559: Anomalies of the Penis and Urethra - p. g0040 30. Chapter 560: Disorders and Anomalies of the Scrotal Contents - p. g0040 31. Chapter 561: Trauma to the Genitourinary Tract - p. g0040 32. Chapter 562: Urinary Lithiasis - p. g0040 33. Part XXIV: Gynecologic Problems of Childhood - p. g0040 34. Chapter 563: Gynecologic History and Physical Examination - p. g0040 35. Chapter 564: Vulvovaginitis - p. g0040 36. Chapter 565: Vaginal Bleeding in the Prepubertal Child - p. g0040 37. Chapter 566: Breast Concerns - p. g0040 38. Chapter 567: Polycystic Ovary Syndrome and Hirsutism - p. g0040 39. Chapter 568: Gynecologic Neoplasms and Adolescent Prevention Methods for Human Papillomavirus - p. g0040 40. Chapter 569: Vulvovaginal and Müllerian Anomalies - p. g0040 41. Chapter 570: Gynecologic Care for Girls With Special Needs - p. g0040 42. Chapter 571: Female Genital Mutilation - p. g0040 43. Part XXV: The Endocrine System - p. g0040 44. Section 1: Disorders of the Hypothalamus and Pituitary Gland - p. g0040 45. Chapter 572: Hormones of the Hypothalamus and Pituitary - p. g0040 46. Chapter 573: Hypopituitarism - p. g0040 47. Chapter 574: Diabetes Insipidus - p. g0040 48. Chapter 575: Other Abnormalities of Arginine Vasopressin Metabolism and Action - p. g0040 49. Chapter 576: Hyperpituitarism, Tall Stature, and Overgrowth Syndromes - p. g0040 50. Chapter 577: Physiology of Puberty - p. g0040 51. Chapter 578: Disorders of Pubertal Development - p. g0040 52. Section 2: Disorders of the Thyroid Gland - p. g0040 53. Chapter 579: Thyroid Development and Physiology - p. g0040 54. Chapter 580: Disorders of Thyroxine-Binding Globulin - p. g0040 55. Chapter 581: Hypothyroidism - p. g0040 56. Chapter 582: Thyroiditis - p. g0040 57. Chapter 583: Goiter - p. g0040 58. Chapter 584: Thyrotoxicosis - p. g0040 59. Chapter 585: Carcinoma of the Thyroid - p. g0040 60. Chapter 586: Autoimmune Polyglandular Syndromes - p. g0040 61. Chapter 587: Multiple Endocrine Neoplasia Syndromes - p. g0040 62. Section 3: Disorders of the Parathyroid Gland - p. g0040 63. Chapter 588: Hormones and Peptides of Calcium Homeostasis and Bone Metabolism - p. g0040 64. Chapter 589: Hypoparathyroidism - p. g0040 65. Chapter 590: Pseudohypoparathyroidism - p. g0040 66. Chapter 591: Hyperparathyroidism - p. g0040 67. Section 4: Disorders of the Adrenal Gland - p. g0040 68. Chapter 592: Physiology of the Adrenal Gland - p. g0040 69. Chapter 593: Adrenocortical Insufficiency - p. g0040 70. Chapter 594: Congenital Adrenal Hyperplasia and Related Disorders - p. g0040 71. Chapter 595: Adrenocortical Tumors and Masses - p. g0040 72. Chapter 596: Virilizing and Feminizing Adrenal Tumors - p. g0040 73. Chapter 597: Cushing Syndrome - p. g0040 74. Chapter 598: Primary Aldosteronism - p. g0040 75. Chapter 599: Pheochromocytoma - p. g0040 76. Section 5: Disorders of the Gonads - p. g0040 77. Chapter 600: Development and Function of the Gonads - p. g0040 78. Chapter 601: Hypofunction of the Testes - p. g0040 79. 601.1 Hypergonadotropic Hypogonadism in the Male (Primary Hypogonadism) - p. g0040 80. 601.2 Hypogonadotropic Hypogonadism in the Male (Secondary Hypogonadism) - p. g0040 81. Chapter 602: Pseudoprecocity Resulting From Tumors of the Testes - p. g0040 82. Chapter 603: Gynecomastia - p. g0040 83. Chapter 604: Hypofunction of the Ovaries - p. g0040 84. Chapter 605: Pseudoprecocity Resulting From Lesions of the Ovary - p. g0040 85. Chapter 606: Disorders of Sex Development - p. g0040 86. Section 6: Diabetes Mellitus in Children - p. g0040 87. Chapter 607: Diabetes Mellitus - p. g0040 88. Part XXVI: The Nervous System - p. g0040 89. Chapter 608: Neurologic Evaluation - p. g0040 90. Chapter 609: Congenital Anomalies of the Central Nervous System - p. g0040 91. Chapter 610: Deformational Plagiocephaly - p. g0040 92. Chapter 611: Seizures in Childhood - p. g0040 93. Chapter 612: Conditions That Mimic Seizures - p. g0040 94. Chapter 613: Headaches - p. g0040 95. Chapter 614: Neurocutaneous Syndromes - p. g0040 96. Chapter 615: Movement Disorders - p. g0040 97. Chapter 616: Encephalopathies - p. g0040 98. Chapter 617: Neurodegenerative Disorders of Childhood - p. g0040 99. Chapter 618: Demyelinating Disorders of the Central Nervous System - p. g0040 100. Chapter 619: Pediatric Stroke - p. g0040 101. Chapter 620: Central Nervous System Vasculitis - p. g0040 102. Chapter 621: Central Nervous System Infections - p. g0040 103. Chapter 622: Brain Abscess - p. g0040 104. Chapter 623: Idiopathic Intracranial Hypertension (Pseudotumor Cerebri) - p. g0040 105. Chapter 624: Spinal Cord Disorders - p. g0040 106. Part XXVII: Neuromuscular Disorders - p. g0040 107. Chapter 625: Evaluation and Investigation of Neuromuscular Disorders - p. g0040 108. Chapter 626: Developmental Disorders of Muscle - p. g0040 109. Chapter 627: Muscular Dystrophies - p. g0040 110. Chapter 628: Endocrine and Toxic Myopathies - p. g0040 111. Chapter 629: Metabolic Myopathies and Channelopathies - p. g0040 112. Chapter 630: Disorders of Neuromuscular Transmission and of Motor Neurons - p. g0040 113. Chapter 631: Hereditary Motor-Sensory Neuropathies - p. g0040 114. Chapter 632: Toxic Neuropathies - p. g0040 115. Chapter 633: Autonomic Neuropathies - p. g0040 116. Chapter 634: Guillain-Barré Syndrome - p. g0040 117. Chapter 635: Bell Palsy - p. g0040 118. Part XXVIII: Disorders of the Eye - p. g0040 119. Chapter 636: Growth and Development of the Eye - p. g0040 120. Chapter 637: Examination of the Eye - p. g0040 121. Chapter 638: Abnormalities of Refraction and Accommodation - p. g0040 122. Chapter 639: Disorders of Vision - p. g0040 123. Chapter 640: Abnormalities of Pupil and Iris - p. g0040 124. Chapter 641: Disorders of Eye Movement and Alignment - p. g0040 125. Chapter 642: Abnormalities of the Lids - p. g0040 126. Chapter 643: Disorders of the Lacrimal System - p. g0040 127. Chapter 644: Disorders of the Conjunctiva - p. g0040 128. Chapter 645: Abnormalities of the Cornea - p. g0040 129. Chapter 646: Abnormalities of the Lens - p. g0040 130. Chapter 647: Disorders of the Uveal Tract - p. g0040 131. Chapter 648: Disorders of the Retina and Vitreous - p. g0040 132. Chapter 649: Abnormalities of the Optic Nerve - p. g0040 133. Chapter 650: Childhood Glaucoma - p. g0040 134. Chapter 651: Orbital Abnormalities - p. g0040 135. Chapter 652: Orbital Infections - p. g0040 136. Chapter 653: Injuries to the Eye - p. g0040 137. Part XXIX: The Ear - p. g0040 138. Chapter 654: General Considerations and Evaluation of the Ear - p. g0040 139. Chapter 655: Hearing Loss - p. g0040 140. Chapter 656: Congenital Malformations of the Ear - p. g0040 141. Chapter 657: External Otitis (Otitis Externa) - p. g0040 142. Chapter 658: Otitis Media - p. g0040 143. Chapter 659: Acute Mastoiditis - p. g0040 144. Chapter 660: The Inner Ear and Diseases of the Bony Labyrinth - p. g0040 145. Chapter 661: Traumatic Injuries of the Ear and Temporal Bone - p. g0040 146. Chapter 662: Tumors of the Ear and Temporal Bone - p. g0040 147. Part XXX: The Skin - p. g0040 148. Chapter 663: Morphology of the Skin - p. g0040 149. Chapter 664: Dermatologic Evaluation of the Patient - p. g0040 150. Chapter 665: Principles of Dermatologic Therapy - p. g0040 151. Chapter 666: Dermatologic Diseases of the Neonate - p. g0040 152. Chapter 667: Cutaneous Defects - p. g0040 153. Chapter 668: Ectodermal Dysplasias - p. g0040 154. Chapter 669: Vascular Disorders - p. g0040 155. Chapter 670: Cutaneous Nevi - p. g0040 156. Chapter 671: Hyperpigmented Lesions - p. g0040 157. Chapter 672: Hypopigmented Lesions - p. g0040 158. Chapter 673: Vesiculobullous Disorders - p. g0040 159. Chapter 674: Eczematous Disorders - p. g0040 160. Chapter 675: Photosensitivity - p. g0040 161. Chapter 676: Diseases of the Epidermis - p. g0040 162. Chapter 677: Disorders of Keratinization - p. g0040 163. Chapter 678: Diseases of the Dermis - p. g0040 164. Chapter 679: Ehlers-Danlos Syndrome - p. g0040 165. Chapter 680: Diseases of Subcutaneous Tissue - p. g0040 166. Chapter 681: Disorders of the Sweat Glands - p. g0040 167. Chapter 682: Disorders of Hair - p. g0040 168. Chapter 683: Disorders of the Nails - p. g0040 169. Chapter 684: Disorders of the Mucous Membranes - p. g0040 170. Chapter 685: Cutaneous Bacterial Infections - p. g0040 171. Chapter 686: Cutaneous Fungal Infections - p. g0040 172. Chapter 687: Cutaneous Viral Infections - p. g0040 173. Chapter 688: Arthropod Bites and Infestations - p. g0040 174. Chapter 689: Acne - p. g0040 175. Chapter 690: Tumors of the Skin - p. g0040 176. Chapter 691: Nutritional Dermatoses - p. g0040 177. Part XXXI: Bone and Joint Disorders - p. g0040 178. Section 1: Orthopedic Problems - p. g0040 179. Chapter 692: Growth and Development - p. g0040 180. Chapter 693: Orthopedic Evaluation of the Child - p. g0040 181. Chapter 694: The Foot and Toes - p. g0040 182. Chapter 695: Torsional and Angular Deformities of the Limb - p. g0040 183. Chapter 696: Leg-Length Discrepancy - p. g0040 184. Chapter 697: The Knee - p. g0040 185. Chapter 698: The Hip - p. g0040 186. Chapter 699: The Spine - p. g0040 187. Chapter 700: The Neck - p. g0040 188. Chapter 701: The Upper Limb - p. g0040 189. Chapter 702: Arthrogryposis - p. g0040 190. Chapter 703: Common Fractures - p. g0040 191. Chapter 704: Osteomyelitis - p. g0040 192. Chapter 705: Septic Arthritis - p. g0040 193. Section 2: Sports Medicine - p. g0040 194. Chapter 706: Epidemiology and Prevention of Injuries - p. g0040 195. Chapter 707: Management of Musculoskeletal Injury - p. g0040 196. Chapter 708: Sports-Related Traumatic Brain Injury (Concussion) - p. g0040 197. Chapter 709: Cervical Spine Injuries - p. g0040 198. Chapter 710: Heat Injuries - p. g0040 199. Chapter 711: Female Athletes: Menstrual Problems and the Risk of Osteopenia - p. g0040 200. Chapter 712: Performance-Enhancing Aids - p. g0040 201. Chapter 713: Specific Sports and Associated Injuries - p. g0040 202. Section 3: The Skeletal Dysplasias - p. g0040 203. Chapter 714: General Considerations in Skeletal Dysplasias - p. g0040 204. Chapter 715: Disorders Involving Cartilage Matrix Proteins - p. g0040 205. Chapter 716: Disorders Involving Transmembrane Receptors - p. g0040 206. Chapter 717: Disorders Involving Ion Transporters - p. g0040 207. Chapter 718: Disorders Involving Transcription Factors - p. g0040 208. Chapter 719: Disorders Involving Defective Bone Resorption - p. g0040 209. Chapter 720: Other Inherited Disorders of Skeletal Development - p. g0040 210. Chapter 721: Osteogenesis Imperfecta - p. g0040 211. Chapter 722: Marfan Syndrome - p. g0040 212. Section 4: Metabolic Bone Disease - p. g0040 213. Chapter 723: Bone Structure, Growth, and Hormonal Regulation - p. g0040 214. Chapter 724: Hypophosphatasia - p. g0040 215. Chapter 725: Hyperphosphatasia - p. g0040 216. Chapter 726: Osteoporosis - p. g0040 217. Part XXXII: Rehabilitation Medicine - p. g0040 218. Chapter 727: Evaluation of the Child for Rehabilitative Services - p. g0040 219. Chapter 728: Rehabilitation for Severe Traumatic Brain Injury - p. g0040 220. Chapter 729: Spinal Cord Injury and Autonomic Dysreflexia Management - p. g0040 221. Chapter 730: Spasticity - p. g0040 222. Chapter 731: Birth Brachial Plexus Palsy - p. g0040 223. Chapter 732: Meningomyelocele (Spina Bifida) - p. g0040 224. Chapter 733: Ambulation Assistance - p. g0040 225. Chapter 734: Health and Wellness for Children With Disabilities - p. g0040 226. Part XXXIII: Environmental Health - p. g0040 227. Chapter 735: Overview of Environmental Health and Children - p. g0040 228. Chapter 736: Biologic Effects of Ionizing Radiation on Children - p. g0040 229. Chapter 737: Chemical Pollutants - p. g0040 230. Chapter 738: Heavy Metal Intoxication - p. g0040 231. Chapter 739: Lead Poisoning - p. g0040 232. Chapter 740: Nonbacterial Food Poisoning - p. g0040 233. Chapter 741: Biologic and Chemical Terrorism* - p. g0040 234. Chapter 742: Mass Psychogenic Illness - p. g0040 235. Chapter 743: Animal and Human Bites - p. g0040 236. Chapter 744: Rat Bite Fever - p. g0040 237. Chapter 745: Monkeypox - p. g0040 238. Chapter 746: Envenomations - p. g0040 239. Part XXXIV: Laboratory Medicine - p. g0040 240. Chapter 747: Laboratory Testing in Infants and Children - p. g0040 241. Chapter 748: Reference Intervals for Laboratory Tests and Procedures - p. g0040 242. Index - p. g0040

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Descripción

Welcome to the 21st Edition of Nelson Textbook of Pediatrics – the reference of choice among pediatricians, pediatric residents, and others involved in the care of young patients. This fully revised edition continues to provide the breadth and depth of knowledge you expect from Nelson, while also keeping you up to date with new advances in the science and art of pediatric practice. Authoritative and reader-friendly, it delivers the information you need in a concise, easy-to-use format for everyday reference and study. From rapidly changing diagnostic and treatment protocols to new technologies to the wide range of biologic, psychologic, and social problems faced by children today, this comprehensive reference keeps you on the cutting edge of the very best in pediatric care.

  • Includes more than 70 new chapters, including Postural Orthostatic Tachycardia Syndrome (POTS), Rare and Undiagnosed Diseases, Approach to Mitochondrial Disorders, Electronic Nicotine Delivery Systems, Zika, update on Ebola, Epigenetics, Autoimmune Encephalitis, Global Health, Racism, Media Violence, Strategies for Health Behavior Change, Positive Parenting, and many more.
  • Features hundreds of new figures and tables throughout for visual clarity and quick reference.
  • Offers new and expanded information on CRISPR gene editing; LGBT health care; gun violence; vaccinations; immune treatment with CAR-T cells; new technology in imaging and genomics; new protocols in cancer, genetics, immunology, and pulmonary medicine; and much more.
  • Provides fresh perspectives from four new associate editors: Nathan J. Blum of The Children’s Hospital of Philadelphia; Karen Wilson of Mt. Sinai School of Medicine in New York; Samir S. Shah of Cincinnati Children’s Hospital Medical Center; and Robert C. Tasker of Boston Children’s Hospital.
  • Remains your indispensable source for definitive, evidence-based answers on every aspect of pediatric care.

1. Chapter 535: Introduction to Glomerular Diseases - p. g0040 2. Section 2: Conditions Particularly Associated with Hematuria - p. g0040 3. Chapter 536: Clinical Evaluation of the Child With Hematuria - p. g0040 4. Chapter 537: Isolated Glomerular Diseases Associated With Recurrent Gross Hematuria - p. g0040 5. Chapter 538: Multisystem Disease Associated With Hematuria - p. g0040 6. Chapter 539: Tubulointerstitial Disease Associated With Hematuria - p. g0040 7. Chapter 540: Vascular Diseases Associated with Hematuria - p. g0040 8. Chapter 541: Anatomic Abnormalities Associated With Hematuria - p. g0040 9. Chapter 542: Lower Urinary Tract Causes of Hematuria - p. g0040 10. Section 3: Conditions Particularly Associated with Proteinuria - p. g0040 11. Chapter 543: Clinical Evaluation of the Child With Proteinuria - p. g0040 12. Chapter 544: Conditions Associated With Proteinuria - p. g0040 13. Chapter 545: Nephrotic Syndrome - p. g0040 14. Section 4: Tubular Disorders - p. g0040 15. Chapter 546: Tubular Function - p. g0040 16. Chapter 547: Renal Tubular Acidosis - p. g0040 17. Chapter 548: Nephrogenic Diabetes Insipidus - p. g0040 18. Chapter 549: Inherited Tubular Transport Abnormalities - p. g0040 19. Chapter 550: Renal Failure - p. g0040 20. Chapter 551: Renal Transplantation - p. g0040 21. Part XXIII: Urologic Disorders in Infants and Children - p. g0040 22. Chapter 552: Congenital Anomalies and Dysgenesis of the Kidneys - p. g0040 23. Chapter 553: Urinary Tract Infections - p. g0040 24. Chapter 554: Vesicoureteral Reflux - p. g0040 25. Chapter 555: Obstruction of the Urinary Tract - p. g0040 26. Chapter 556: Anomalies of the Bladder - p. g0040 27. Chapter 557: Neuropathic Bladder - p. g0040 28. Chapter 558: Enuresis and Voiding Dysfunction - p. g0040 29. Chapter 559: Anomalies of the Penis and Urethra - p. g0040 30. Chapter 560: Disorders and Anomalies of the Scrotal Contents - p. g0040 31. Chapter 561: Trauma to the Genitourinary Tract - p. g0040 32. Chapter 562: Urinary Lithiasis - p. g0040 33. Part XXIV: Gynecologic Problems of Childhood - p. g0040 34. Chapter 563: Gynecologic History and Physical Examination - p. g0040 35. Chapter 564: Vulvovaginitis - p. g0040 36. Chapter 565: Vaginal Bleeding in the Prepubertal Child - p. g0040 37. Chapter 566: Breast Concerns - p. g0040 38. Chapter 567: Polycystic Ovary Syndrome and Hirsutism - p. g0040 39. Chapter 568: Gynecologic Neoplasms and Adolescent Prevention Methods for Human Papillomavirus - p. g0040 40. Chapter 569: Vulvovaginal and Müllerian Anomalies - p. g0040 41. Chapter 570: Gynecologic Care for Girls With Special Needs - p. g0040 42. Chapter 571: Female Genital Mutilation - p. g0040 43. Part XXV: The Endocrine System - p. g0040 44. Section 1: Disorders of the Hypothalamus and Pituitary Gland - p. g0040 45. Chapter 572: Hormones of the Hypothalamus and Pituitary - p. g0040 46. Chapter 573: Hypopituitarism - p. g0040 47. Chapter 574: Diabetes Insipidus - p. g0040 48. Chapter 575: Other Abnormalities of Arginine Vasopressin Metabolism and Action - p. g0040 49. Chapter 576: Hyperpituitarism, Tall Stature, and Overgrowth Syndromes - p. g0040 50. Chapter 577: Physiology of Puberty - p. g0040 51. Chapter 578: Disorders of Pubertal Development - p. g0040 52. Section 2: Disorders of the Thyroid Gland - p. g0040 53. Chapter 579: Thyroid Development and Physiology - p. g0040 54. Chapter 580: Disorders of Thyroxine-Binding Globulin - p. g0040 55. Chapter 581: Hypothyroidism - p. g0040 56. Chapter 582: Thyroiditis - p. g0040 57. Chapter 583: Goiter - p. g0040 58. Chapter 584: Thyrotoxicosis - p. g0040 59. Chapter 585: Carcinoma of the Thyroid - p. g0040 60. Chapter 586: Autoimmune Polyglandular Syndromes - p. g0040 61. Chapter 587: Multiple Endocrine Neoplasia Syndromes - p. g0040 62. Section 3: Disorders of the Parathyroid Gland - p. g0040 63. Chapter 588: Hormones and Peptides of Calcium Homeostasis and Bone Metabolism - p. g0040 64. Chapter 589: Hypoparathyroidism - p. g0040 65. Chapter 590: Pseudohypoparathyroidism - p. g0040 66. Chapter 591: Hyperparathyroidism - p. g0040 67. Section 4: Disorders of the Adrenal Gland - p. g0040 68. Chapter 592: Physiology of the Adrenal Gland - p. g0040 69. Chapter 593: Adrenocortical Insufficiency - p. g0040 70. Chapter 594: Congenital Adrenal Hyperplasia and Related Disorders - p. g0040 71. Chapter 595: Adrenocortical Tumors and Masses - p. g0040 72. Chapter 596: Virilizing and Feminizing Adrenal Tumors - p. g0040 73. Chapter 597: Cushing Syndrome - p. g0040 74. Chapter 598: Primary Aldosteronism - p. g0040 75. Chapter 599: Pheochromocytoma - p. g0040 76. Section 5: Disorders of the Gonads - p. g0040 77. Chapter 600: Development and Function of the Gonads - p. g0040 78. Chapter 601: Hypofunction of the Testes - p. g0040 79. 601.1 Hypergonadotropic Hypogonadism in the Male (Primary Hypogonadism) - p. g0040 80. 601.2 Hypogonadotropic Hypogonadism in the Male (Secondary Hypogonadism) - p. g0040 81. Chapter 602: Pseudoprecocity Resulting From Tumors of the Testes - p. g0040 82. Chapter 603: Gynecomastia - p. g0040 83. Chapter 604: Hypofunction of the Ovaries - p. g0040 84. Chapter 605: Pseudoprecocity Resulting From Lesions of the Ovary - p. g0040 85. Chapter 606: Disorders of Sex Development - p. g0040 86. Section 6: Diabetes Mellitus in Children - p. g0040 87. Chapter 607: Diabetes Mellitus - p. g0040 88. Part XXVI: The Nervous System - p. g0040 89. Chapter 608: Neurologic Evaluation - p. g0040 90. Chapter 609: Congenital Anomalies of the Central Nervous System - p. g0040 91. Chapter 610: Deformational Plagiocephaly - p. g0040 92. Chapter 611: Seizures in Childhood - p. g0040 93. Chapter 612: Conditions That Mimic Seizures - p. g0040 94. Chapter 613: Headaches - p. g0040 95. Chapter 614: Neurocutaneous Syndromes - p. g0040 96. Chapter 615: Movement Disorders - p. g0040 97. Chapter 616: Encephalopathies - p. g0040 98. Chapter 617: Neurodegenerative Disorders of Childhood - p. g0040 99. Chapter 618: Demyelinating Disorders of the Central Nervous System - p. g0040 100. Chapter 619: Pediatric Stroke - p. g0040 101. Chapter 620: Central Nervous System Vasculitis - p. g0040 102. Chapter 621: Central Nervous System Infections - p. g0040 103. Chapter 622: Brain Abscess - p. g0040 104. Chapter 623: Idiopathic Intracranial Hypertension (Pseudotumor Cerebri) - p. g0040 105. Chapter 624: Spinal Cord Disorders - p. g0040 106. Part XXVII: Neuromuscular Disorders - p. g0040 107. Chapter 625: Evaluation and Investigation of Neuromuscular Disorders - p. g0040 108. Chapter 626: Developmental Disorders of Muscle - p. g0040 109. Chapter 627: Muscular Dystrophies - p. g0040 110. Chapter 628: Endocrine and Toxic Myopathies - p. g0040 111. Chapter 629: Metabolic Myopathies and Channelopathies - p. g0040 112. Chapter 630: Disorders of Neuromuscular Transmission and of Motor Neurons - p. g0040 113. Chapter 631: Hereditary Motor-Sensory Neuropathies - p. g0040 114. Chapter 632: Toxic Neuropathies - p. g0040 115. Chapter 633: Autonomic Neuropathies - p. g0040 116. Chapter 634: Guillain-Barré Syndrome - p. g0040 117. Chapter 635: Bell Palsy - p. g0040 118. Part XXVIII: Disorders of the Eye - p. g0040 119. Chapter 636: Growth and Development of the Eye - p. g0040 120. Chapter 637: Examination of the Eye - p. g0040 121. Chapter 638: Abnormalities of Refraction and Accommodation - p. g0040 122. Chapter 639: Disorders of Vision - p. g0040 123. Chapter 640: Abnormalities of Pupil and Iris - p. g0040 124. Chapter 641: Disorders of Eye Movement and Alignment - p. g0040 125. Chapter 642: Abnormalities of the Lids - p. g0040 126. Chapter 643: Disorders of the Lacrimal System - p. g0040 127. Chapter 644: Disorders of the Conjunctiva - p. g0040 128. Chapter 645: Abnormalities of the Cornea - p. g0040 129. Chapter 646: Abnormalities of the Lens - p. g0040 130. Chapter 647: Disorders of the Uveal Tract - p. g0040 131. Chapter 648: Disorders of the Retina and Vitreous - p. g0040 132. Chapter 649: Abnormalities of the Optic Nerve - p. g0040 133. Chapter 650: Childhood Glaucoma - p. g0040 134. Chapter 651: Orbital Abnormalities - p. g0040 135. Chapter 652: Orbital Infections - p. g0040 136. Chapter 653: Injuries to the Eye - p. g0040 137. Part XXIX: The Ear - p. g0040 138. Chapter 654: General Considerations and Evaluation of the Ear - p. g0040 139. Chapter 655: Hearing Loss - p. g0040 140. Chapter 656: Congenital Malformations of the Ear - p. g0040 141. Chapter 657: External Otitis (Otitis Externa) - p. g0040 142. Chapter 658: Otitis Media - p. g0040 143. Chapter 659: Acute Mastoiditis - p. g0040 144. Chapter 660: The Inner Ear and Diseases of the Bony Labyrinth - p. g0040 145. Chapter 661: Traumatic Injuries of the Ear and Temporal Bone - p. g0040 146. Chapter 662: Tumors of the Ear and Temporal Bone - p. g0040 147. Part XXX: The Skin - p. g0040 148. Chapter 663: Morphology of the Skin - p. g0040 149. Chapter 664: Dermatologic Evaluation of the Patient - p. g0040 150. Chapter 665: Principles of Dermatologic Therapy - p. g0040 151. Chapter 666: Dermatologic Diseases of the Neonate - p. g0040 152. Chapter 667: Cutaneous Defects - p. g0040 153. Chapter 668: Ectodermal Dysplasias - p. g0040 154. Chapter 669: Vascular Disorders - p. g0040 155. Chapter 670: Cutaneous Nevi - p. g0040 156. Chapter 671: Hyperpigmented Lesions - p. g0040 157. Chapter 672: Hypopigmented Lesions - p. g0040 158. Chapter 673: Vesiculobullous Disorders - p. g0040 159. Chapter 674: Eczematous Disorders - p. g0040 160. Chapter 675: Photosensitivity - p. g0040 161. Chapter 676: Diseases of the Epidermis - p. g0040 162. Chapter 677: Disorders of Keratinization - p. g0040 163. Chapter 678: Diseases of the Dermis - p. g0040 164. Chapter 679: Ehlers-Danlos Syndrome - p. g0040 165. Chapter 680: Diseases of Subcutaneous Tissue - p. g0040 166. Chapter 681: Disorders of the Sweat Glands - p. g0040 167. Chapter 682: Disorders of Hair - p. g0040 168. Chapter 683: Disorders of the Nails - p. g0040 169. Chapter 684: Disorders of the Mucous Membranes - p. g0040 170. Chapter 685: Cutaneous Bacterial Infections - p. g0040 171. Chapter 686: Cutaneous Fungal Infections - p. g0040 172. Chapter 687: Cutaneous Viral Infections - p. g0040 173. Chapter 688: Arthropod Bites and Infestations - p. g0040 174. Chapter 689: Acne - p. g0040 175. Chapter 690: Tumors of the Skin - p. g0040 176. Chapter 691: Nutritional Dermatoses - p. g0040 177. Part XXXI: Bone and Joint Disorders - p. g0040 178. Section 1: Orthopedic Problems - p. g0040 179. Chapter 692: Growth and Development - p. g0040 180. Chapter 693: Orthopedic Evaluation of the Child - p. g0040 181. Chapter 694: The Foot and Toes - p. g0040 182. Chapter 695: Torsional and Angular Deformities of the Limb - p. g0040 183. Chapter 696: Leg-Length Discrepancy - p. g0040 184. Chapter 697: The Knee - p. g0040 185. Chapter 698: The Hip - p. g0040 186. Chapter 699: The Spine - p. g0040 187. Chapter 700: The Neck - p. g0040 188. Chapter 701: The Upper Limb - p. g0040 189. Chapter 702: Arthrogryposis - p. g0040 190. Chapter 703: Common Fractures - p. g0040 191. Chapter 704: Osteomyelitis - p. g0040 192. Chapter 705: Septic Arthritis - p. g0040 193. Section 2: Sports Medicine - p. g0040 194. Chapter 706: Epidemiology and Prevention of Injuries - p. g0040 195. Chapter 707: Management of Musculoskeletal Injury - p. g0040 196. Chapter 708: Sports-Related Traumatic Brain Injury (Concussion) - p. g0040 197. Chapter 709: Cervical Spine Injuries - p. g0040 198. Chapter 710: Heat Injuries - p. g0040 199. Chapter 711: Female Athletes: Menstrual Problems and the Risk of Osteopenia - p. g0040 200. Chapter 712: Performance-Enhancing Aids - p. g0040 201. Chapter 713: Specific Sports and Associated Injuries - p. g0040 202. Section 3: The Skeletal Dysplasias - p. g0040 203. Chapter 714: General Considerations in Skeletal Dysplasias - p. g0040 204. Chapter 715: Disorders Involving Cartilage Matrix Proteins - p. g0040 205. Chapter 716: Disorders Involving Transmembrane Receptors - p. g0040 206. Chapter 717: Disorders Involving Ion Transporters - p. g0040 207. Chapter 718: Disorders Involving Transcription Factors - p. g0040 208. Chapter 719: Disorders Involving Defective Bone Resorption - p. g0040 209. Chapter 720: Other Inherited Disorders of Skeletal Development - p. g0040 210. Chapter 721: Osteogenesis Imperfecta - p. g0040 211. Chapter 722: Marfan Syndrome - p. g0040 212. Section 4: Metabolic Bone Disease - p. g0040 213. Chapter 723: Bone Structure, Growth, and Hormonal Regulation - p. g0040 214. Chapter 724: Hypophosphatasia - p. g0040 215. Chapter 725: Hyperphosphatasia - p. g0040 216. Chapter 726: Osteoporosis - p. g0040 217. Part XXXII: Rehabilitation Medicine - p. g0040 218. Chapter 727: Evaluation of the Child for Rehabilitative Services - p. g0040 219. Chapter 728: Rehabilitation for Severe Traumatic Brain Injury - p. g0040 220. Chapter 729: Spinal Cord Injury and Autonomic Dysreflexia Management - p. g0040 221. Chapter 730: Spasticity - p. g0040 222. Chapter 731: Birth Brachial Plexus Palsy - p. g0040 223. Chapter 732: Meningomyelocele (Spina Bifida) - p. g0040 224. Chapter 733: Ambulation Assistance - p. g0040 225. Chapter 734: Health and Wellness for Children With Disabilities - p. g0040 226. Part XXXIII: Environmental Health - p. g0040 227. Chapter 735: Overview of Environmental Health and Children - p. g0040 228. Chapter 736: Biologic Effects of Ionizing Radiation on Children - p. g0040 229. Chapter 737: Chemical Pollutants - p. g0040 230. Chapter 738: Heavy Metal Intoxication - p. g0040 231. Chapter 739: Lead Poisoning - p. g0040 232. Chapter 740: Nonbacterial Food Poisoning - p. g0040 233. Chapter 741: Biologic and Chemical Terrorism* - p. g0040 234. Chapter 742: Mass Psychogenic Illness - p. g0040 235. Chapter 743: Animal and Human Bites - p. g0040 236. Chapter 744: Rat Bite Fever - p. g0040 237. Chapter 745: Monkeypox - p. g0040 238. Chapter 746: Envenomations - p. g0040 239. Part XXXIV: Laboratory Medicine - p. g0040 240. Chapter 747: Laboratory Testing in Infants and Children - p. g0040 241. Chapter 748: Reference Intervals for Laboratory Tests and Procedures - p. g0040 242. Index - p. g0040

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