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Recent advances in neonatal hematology, largely made by the authors of these chapters, are likely to generate wide spread and long-term improvements in outcomes, as well as reductions in costs of care. Publication of these advances in a single volume will facilitate dissemination of these techniques and practices. The advances include neuroprotection from erythropoietic stimulators, improved guidelines for platelet transfusions, evidence-based guidelines for FFP administration, improved diagnostic methods for genetic causes of severe neonatal jaundice, more accurate definitions of hematological perturbations in necrotizing enterocolitis and sepsis, and reduction in transfusions and in IVH rates by cord milking/delayed clamping.

1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Copyright - p. 4 5. Contributors - p. 5 6. CME Accreditation Page - p. 8 7. Forthcoming Issues - p. 9 8. Foreword: Neonatal Hematology and Transfusion Medicine: What We Can Learn from Pediatric Oncology Groups - p. 10 9. Preface: The Expanding Evidence Base to Guide Neonatal Hematology and Transfusion Medicine Practice - p. 11 10. Erythropoietin and Neonatal Neuroprotection - p. 12 11. Reference Intervals in Neonatal Hematology - p. 20 12. Neonatal Transfusion Medicine - p. 22 13. Hemolytic Disorders Causing Severe Neonatal Hyperbilirubinemia - p. 32 14. Plasma Biomarkers of Oxidative Stress in Neonatal Brain Injury - p. 38 15. Umbilical Cord Blood—An Untapped Resource - p. 44 16. Darbepoetin Administration in Term and Preterm Neonates - p. 51 17. Immunologic and Hematological Abnormalities in Necrotizing Enterocolitis - p. 56 18. Hematologic Aspects of Early and Late-Onset Sepsis in Preterm Infants - p. 68 19. Stem Cells - p. 74 20. Platelet Transfusions in the Neonatal Intensive Care Unit - p. 83 21. Neonatal Platelet Function - p. 90 22. Fresh Frozen Plasma Administration in the Neonatal Intensive Care Unit - p. 98 23. Thrombosis in the Neonatal Intensive Care Unit - p. 105 24. Index - p. 116

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Recent advances in neonatal hematology, largely made by the authors of these chapters, are likely to generate wide spread and long-term improvements in outcomes, as well as reductions in costs of care. Publication of these advances in a single volume will facilitate dissemination of these techniques and practices. The advances include neuroprotection from erythropoietic stimulators, improved guidelines for platelet transfusions, evidence-based guidelines for FFP administration, improved diagnostic methods for genetic causes of severe neonatal jaundice, more accurate definitions of hematological perturbations in necrotizing enterocolitis and sepsis, and reduction in transfusions and in IVH rates by cord milking/delayed clamping.

1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Copyright - p. 4 5. Contributors - p. 5 6. CME Accreditation Page - p. 8 7. Forthcoming Issues - p. 9 8. Foreword: Neonatal Hematology and Transfusion Medicine: What We Can Learn from Pediatric Oncology Groups - p. 10 9. Preface: The Expanding Evidence Base to Guide Neonatal Hematology and Transfusion Medicine Practice - p. 11 10. Erythropoietin and Neonatal Neuroprotection - p. 12 11. Reference Intervals in Neonatal Hematology - p. 20 12. Neonatal Transfusion Medicine - p. 22 13. Hemolytic Disorders Causing Severe Neonatal Hyperbilirubinemia - p. 32 14. Plasma Biomarkers of Oxidative Stress in Neonatal Brain Injury - p. 38 15. Umbilical Cord Blood—An Untapped Resource - p. 44 16. Darbepoetin Administration in Term and Preterm Neonates - p. 51 17. Immunologic and Hematological Abnormalities in Necrotizing Enterocolitis - p. 56 18. Hematologic Aspects of Early and Late-Onset Sepsis in Preterm Infants - p. 68 19. Stem Cells - p. 74 20. Platelet Transfusions in the Neonatal Intensive Care Unit - p. 83 21. Neonatal Platelet Function - p. 90 22. Fresh Frozen Plasma Administration in the Neonatal Intensive Care Unit - p. 98 23. Thrombosis in the Neonatal Intensive Care Unit - p. 105 24. Index - p. 116

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