Neurobiology of the Placebo Effect, Part I, Volume 138 in the International Review of Neurobiology series, is the first of two volumes that provide the latest placebo studies in clinically relevant models. Placebo responses effects are not merely a psychological, but a complex psycho-neuro-biological process that requires activation of distinct brain areas. This book discusses current research and projects on the involved brain circuitry and neurotransmitter systems. Specific chapters cover such topics as pharmacological conditioning of the endocrine and immune system, expectancy modulation of opioid neurotransmission, nocebo effects in visceral pain, and conditioning as a higher-order cognitive phenomenon, amongst other topics.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xi 6. Preface: The Fascinating Mechanisms and Implications of the Placebo Effect - p. xv 7. Chapter One: Placebo Analgesia in Rodents: Current and Future Research - p. xx 8. Chapter Two: Expectancy Modulation of Opioid Neurotransmission - p. 15 9. Chapter Three: Placebo Effects in the Immune System - p. 37 10. Chapter Four: Human Pharmacological Conditioning of the Immune and Endocrine System: Challenges and Opportunities - p. 59 11. Chapter Five: Response Expectancy and the Placebo Effect - p. 80 12. Chapter Six: A Functional-Cognitive Perspective on the Relation Between Conditioning and Placebo Research - p. 93 13. Chapter Seven: The Application of Persuasion Theory to Placebo Effects - p. 111 14. Chapter Eight: Mindsets Matter: A New Framework for Harnessing the Placebo Effect in Modern Medicine - p. 136 15. Chapter Nine: The Role of Social and Interpersonal Factors in Placebo Analgesia - p. 160 16. Chapter Ten: What Is Minimally Required to Elicit Placebo Effects? - p. 179 17. Chapter Eleven: Critical Life Functions: Can Placebo Replace Oxygen? - p. 199 18. Chapter Twelve: Placebos Without Deception: Outcomes, Mechanisms, and Ethics - p. 218 19. Chapter Thirteen: Placebo and Psychotherapy: Differences, Similarities, and Implications - p. 240 20. Chapter Fourteen: Expectation-Focused Psychotherapy to Improve Clinical Outcomes - p. 255 21. Chapter Fifteen: Nocebo Effects: Neurobiological Mechanisms and Strategies for Prevention and Optimizing Treatment - p. 270 22. Chapter Sixteen: Nocebo Effects and Experimental Models in Visceral Pain - p. 283 23. Chapter Seventeen: Using Learning Strategies to Inhibit the Nocebo Effect - p. 306 24. Chapter Eighteen: Can knowledge of Placebo and Nocebo Mechanisms Help Improve Randomized Clinical Trials? - p. 327
Neurobiology of the Placebo Effect, Part I, Volume 138 in the International Review of Neurobiology series, is the first of two volumes that provide the latest placebo studies in clinically relevant models. Placebo responses effects are not merely a psychological, but a complex psycho-neuro-biological process that requires activation of distinct brain areas. This book discusses current research and projects on the involved brain circuitry and neurotransmitter systems. Specific chapters cover such topics as pharmacological conditioning of the endocrine and immune system, expectancy modulation of opioid neurotransmission, nocebo effects in visceral pain, and conditioning as a higher-order cognitive phenomenon, amongst other topics.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xi 6. Preface: The Fascinating Mechanisms and Implications of the Placebo Effect - p. xv 7. Chapter One: Placebo Analgesia in Rodents: Current and Future Research - p. xx 8. Chapter Two: Expectancy Modulation of Opioid Neurotransmission - p. 15 9. Chapter Three: Placebo Effects in the Immune System - p. 37 10. Chapter Four: Human Pharmacological Conditioning of the Immune and Endocrine System: Challenges and Opportunities - p. 59 11. Chapter Five: Response Expectancy and the Placebo Effect - p. 80 12. Chapter Six: A Functional-Cognitive Perspective on the Relation Between Conditioning and Placebo Research - p. 93 13. Chapter Seven: The Application of Persuasion Theory to Placebo Effects - p. 111 14. Chapter Eight: Mindsets Matter: A New Framework for Harnessing the Placebo Effect in Modern Medicine - p. 136 15. Chapter Nine: The Role of Social and Interpersonal Factors in Placebo Analgesia - p. 160 16. Chapter Ten: What Is Minimally Required to Elicit Placebo Effects? - p. 179 17. Chapter Eleven: Critical Life Functions: Can Placebo Replace Oxygen? - p. 199 18. Chapter Twelve: Placebos Without Deception: Outcomes, Mechanisms, and Ethics - p. 218 19. Chapter Thirteen: Placebo and Psychotherapy: Differences, Similarities, and Implications - p. 240 20. Chapter Fourteen: Expectation-Focused Psychotherapy to Improve Clinical Outcomes - p. 255 21. Chapter Fifteen: Nocebo Effects: Neurobiological Mechanisms and Strategies for Prevention and Optimizing Treatment - p. 270 22. Chapter Sixteen: Nocebo Effects and Experimental Models in Visceral Pain - p. 283 23. Chapter Seventeen: Using Learning Strategies to Inhibit the Nocebo Effect - p. 306 24. Chapter Eighteen: Can knowledge of Placebo and Nocebo Mechanisms Help Improve Randomized Clinical Trials? - p. 327
