Neuroimaging in Parkinson’s Disease and Related Disorders discusses the advances of molecular, structural and functional neuroimaging techniques associated with the etiology, pathophysiology, effects and complications of novel therapies in Parkinson’s and related disorders. With new neuroimaging methodologies emerging over the past five years, this book provides a comprehensive overview of new technologies and research. Sections discuss the biomarker value of neuroimaging of the brain to understand disease progression in vivo in actual patients with Parkinson’s disease and related disorders. Readers will be updated on in vivo pathology and pathophysiology in Parkinson’s disease and in a number of related disorders.
Also discussed is the association between clinical symptoms, clinical progression, and molecular, structural, and functional changes in the brain of patients with Parkinson’s disease and related disorders.
1. Section I. Introduction - p. xii 2. Chapter 1. Parkinson's disease and related disorders: the pursuit for reliable readouts and the role of neuroimaging - p. xii 3. Chapter 2. Advances in magnetic resonance imaging - p. 19 4. Chapter 3. Advances in molecular neuroimaging methodology - p. 52 5. Section II. Clinical applications in Parkinson's disease - p. 66 6. Chapter 4. Dopaminergic molecular imaging in familial and idiopathic Parkinson's disease - p. 66 7. Chapter 5. Serotonergic molecular imaging in familial and idiopathic PD - p. 104 8. Chapter 6. Molecular imaging beyond dopamine and serotonin in familial and idiopathic Parkinson’s disease - p. 119 9. Chapter 7. Structural MRI in familial and idiopathic PD - p. 150 10. Chapter 8. Functional MRI in familial and idiopathic PD - p. 199 11. Chapter 9. Molecular imaging in prodromal Parkinson’s disease - p. 250 12. Section III. Clinical applications in lewy body dementias - p. 272 13. Chapter 10. Molecular imaging evidence in favor or against PDD and DLB overlap - p. 272 14. Chapter 11. Magnetic resonance imaging in Parkinson's disease with mild cognitive impairment, Parkinson's disease dementia, and dementia with Lewy bodies - p. 295 15. Section IV. Clinical applications in atypical parkinsonian disorders - p. 307 16. Chapter 12. Neuroimaging in multiple system atrophy - p. 307 17. Chapter 13. Neuroimaging in progressive supranuclear palsy - p. 354 18. Chapter 14. Neuroimaging in corticobasal syndrome - p. 397 19. Section V. Clinical applications in other movement disorders - p. 417 20. Chapter 15. Molecular imaging in Huntington's disease - p. 417 21. Chapter 16. Magnetic resonance imaging in Huntington's disease - p. 448 22. Chapter 17. Neuroimaging in essential tremor - p. 489 23. Chapter 18. Neuroimaging of restless legs syndrome - p. 518 24. Chapter 19. Neuroimaging in dystonia - p. 540 25. Chapter 20. Demyelinating syndromes and movement disorders - p. 566 26. Index - p. 584
Neuroimaging in Parkinson’s Disease and Related Disorders discusses the advances of molecular, structural and functional neuroimaging techniques associated with the etiology, pathophysiology, effects and complications of novel therapies in Parkinson’s and related disorders. With new neuroimaging methodologies emerging over the past five years, this book provides a comprehensive overview of new technologies and research. Sections discuss the biomarker value of neuroimaging of the brain to understand disease progression in vivo in actual patients with Parkinson’s disease and related disorders. Readers will be updated on in vivo pathology and pathophysiology in Parkinson’s disease and in a number of related disorders.
Also discussed is the association between clinical symptoms, clinical progression, and molecular, structural, and functional changes in the brain of patients with Parkinson’s disease and related disorders.
1. Section I. Introduction - p. xii 2. Chapter 1. Parkinson's disease and related disorders: the pursuit for reliable readouts and the role of neuroimaging - p. xii 3. Chapter 2. Advances in magnetic resonance imaging - p. 19 4. Chapter 3. Advances in molecular neuroimaging methodology - p. 52 5. Section II. Clinical applications in Parkinson's disease - p. 66 6. Chapter 4. Dopaminergic molecular imaging in familial and idiopathic Parkinson's disease - p. 66 7. Chapter 5. Serotonergic molecular imaging in familial and idiopathic PD - p. 104 8. Chapter 6. Molecular imaging beyond dopamine and serotonin in familial and idiopathic Parkinson’s disease - p. 119 9. Chapter 7. Structural MRI in familial and idiopathic PD - p. 150 10. Chapter 8. Functional MRI in familial and idiopathic PD - p. 199 11. Chapter 9. Molecular imaging in prodromal Parkinson’s disease - p. 250 12. Section III. Clinical applications in lewy body dementias - p. 272 13. Chapter 10. Molecular imaging evidence in favor or against PDD and DLB overlap - p. 272 14. Chapter 11. Magnetic resonance imaging in Parkinson's disease with mild cognitive impairment, Parkinson's disease dementia, and dementia with Lewy bodies - p. 295 15. Section IV. Clinical applications in atypical parkinsonian disorders - p. 307 16. Chapter 12. Neuroimaging in multiple system atrophy - p. 307 17. Chapter 13. Neuroimaging in progressive supranuclear palsy - p. 354 18. Chapter 14. Neuroimaging in corticobasal syndrome - p. 397 19. Section V. Clinical applications in other movement disorders - p. 417 20. Chapter 15. Molecular imaging in Huntington's disease - p. 417 21. Chapter 16. Magnetic resonance imaging in Huntington's disease - p. 448 22. Chapter 17. Neuroimaging in essential tremor - p. 489 23. Chapter 18. Neuroimaging of restless legs syndrome - p. 518 24. Chapter 19. Neuroimaging in dystonia - p. 540 25. Chapter 20. Demyelinating syndromes and movement disorders - p. 566 26. Index - p. 584
