Due to the current obesity epidemic, non-alcoholic fatty liver disease (NAFLD) is prevalent in a significant portion of the United States patient population. It is being increasingly recognized that NAFLD affects both adults and children and can progress to end stage liver disease with resultant cirrhosis, portal hypertension, and hepatocellular carcinoma. In addition, several extrahepatic conditions may be linked to NAFLD including cardiovascular disease, insulin requiring and type 2 diabetes mellitus, obstructive sleep apnea, colonic adenomas, hyperuricemia, vitamin D deficiency, hyperferritinemia, pancreatic steatosis, hypothyroidism, and polycystic ovarian syndrome. Therapies for NAFLD are evolving rapidly. This issue will analyze patient demographics, risk factors, pathophysiology, patient presentation, and treatments for NAFLD.
1. Cover image - p. Cover 2. Title page - p. Cover 3. Table of Contents - p. Cover 4. Copyright - p. Cover 5. Contributors - p. Cover 6. Forthcoming Issues - p. Cover 7. Preface. Nonalcoholic Fatty Liver Disease - p. Cover 8. Epidemiology of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis in the United States and the Rest of the World - p. Cover 9. The Prevalence and Pathobiology of Nonalcoholic Fatty Liver Disease in Patients of Different Races or Ethnicities - p. Cover 10. The Metabolic Syndrome and Its Influence on Nonalcoholic Steatohepatitis - p. Cover 11. Nonalcoholic Fatty Liver Disease: Lipids and Insulin Resistance - p. Cover 12. Nonalcoholic Fatty Liver Disease and the Gut Microbiome - p. Cover 13. Clinical Presentation and Patient Evaluation in Nonalcoholic Fatty Liver Disease - p. Cover 14. Histology of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis in Adults and Children - p. Cover 15. Progression and Natural History of Nonalcoholic Fatty Liver Disease in Adults - p. Cover 16. The Progression and Natural History of Pediatric Nonalcoholic Fatty Liver Disease - p. Cover 17. Effect of Weight Loss, Diet, Exercise, and Bariatric Surgery on Nonalcoholic Fatty Liver Disease - p. Cover 18. Current Pharmacologic Therapy for Nonalcoholic Fatty Liver Disease - p. Cover 19. Emerging Therapies for Nonalcoholic Fatty Liver Disease - p. Cover 20. Extrahepatic Complications of Nonalcoholic Fatty Liver Disease - p. Cover 21. Nonalcoholic Fatty Liver Disease and Liver Transplantation - p. Cover
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Due to the current obesity epidemic, non-alcoholic fatty liver disease (NAFLD) is prevalent in a significant portion of the United States patient population. It is being increasingly recognized that NAFLD affects both adults and children and can progress to end stage liver disease with resultant cirrhosis, portal hypertension, and hepatocellular carcinoma. In addition, several extrahepatic conditions may be linked to NAFLD including cardiovascular disease, insulin requiring and type 2 diabetes mellitus, obstructive sleep apnea, colonic adenomas, hyperuricemia, vitamin D deficiency, hyperferritinemia, pancreatic steatosis, hypothyroidism, and polycystic ovarian syndrome. Therapies for NAFLD are evolving rapidly. This issue will analyze patient demographics, risk factors, pathophysiology, patient presentation, and treatments for NAFLD.
1. Cover image - p. Cover 2. Title page - p. Cover 3. Table of Contents - p. Cover 4. Copyright - p. Cover 5. Contributors - p. Cover 6. Forthcoming Issues - p. Cover 7. Preface. Nonalcoholic Fatty Liver Disease - p. Cover 8. Epidemiology of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis in the United States and the Rest of the World - p. Cover 9. The Prevalence and Pathobiology of Nonalcoholic Fatty Liver Disease in Patients of Different Races or Ethnicities - p. Cover 10. The Metabolic Syndrome and Its Influence on Nonalcoholic Steatohepatitis - p. Cover 11. Nonalcoholic Fatty Liver Disease: Lipids and Insulin Resistance - p. Cover 12. Nonalcoholic Fatty Liver Disease and the Gut Microbiome - p. Cover 13. Clinical Presentation and Patient Evaluation in Nonalcoholic Fatty Liver Disease - p. Cover 14. Histology of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis in Adults and Children - p. Cover 15. Progression and Natural History of Nonalcoholic Fatty Liver Disease in Adults - p. Cover 16. The Progression and Natural History of Pediatric Nonalcoholic Fatty Liver Disease - p. Cover 17. Effect of Weight Loss, Diet, Exercise, and Bariatric Surgery on Nonalcoholic Fatty Liver Disease - p. Cover 18. Current Pharmacologic Therapy for Nonalcoholic Fatty Liver Disease - p. Cover 19. Emerging Therapies for Nonalcoholic Fatty Liver Disease - p. Cover 20. Extrahepatic Complications of Nonalcoholic Fatty Liver Disease - p. Cover 21. Nonalcoholic Fatty Liver Disease and Liver Transplantation - p. Cover
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